| NOVEMBER 29 - BIRTHS | |
| Richard Ewen Borcherds | |
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British mathematician who won the Fields Medal in 1998 for his for his work in the fields of algebra and geometry, in particular for his proof of the so-called Moonshine conjecture. This conjecture had been formulated at the end of the '70s by the British mathematicians John Conway and Simon Norton and presents two mathematical structures in such an unexpected relationship that the experts gave it the name "Moonshine." In 1989, Borcherds was able to cast some more light on the mathematical background of this topic and to produce a proof for the conjecture. The Moonshine conjecture provides an interrelationship between the so-called "monster group" and elliptic functions. |
| Robert A. Swanson | |
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American chemist who, at age 29, cofounded Genentech, Inc. (1976), a research-based company that pioneered the biotechnology industry. His cofounder, distinguished biochemist, Herbert Boyer, had developed one of the key techniques that opened up the possibility of the transfer of genes from one organism to another. Boyer was a pioneer using restriction enzymes to snip segments of DNA out of cells. In 1977, Genentech began mass- producing their first human protein by splicing a gene into bacteria. In 1978, Genentech created the first drug produced by genetic engineering, human-type insulin. It was also the first biotechnology company to sell its own drug, human growth hormone. |
| Yuan T. Lee | |
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Taiwanese-American chemist who, with Dudley R. Herschbach and John C. Polanyi, received the Nobel Prize for Chemistry in 1986 for his role in the development of chemical-reaction dynamics. As a postdoctoral researcher, Lee experimented with and further developed Herschbach's invention of the "crossed molecular beam technique". This studied reactions between molecules at low pressures by letting beams of molecules and/or atoms meet at one point in space. Lee extended Herschbach's technique, introducing mass spectroscopy to identify the products resulting from the reactions of oxygen and fluorine atoms with complex organic compounds. |
| Guido Pontecorvo | |
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Italian geneticist who discovered the process of genetic recombination in the common soil fungus Aspergillus, and as a result of the discovery of the parasexual cycle, the originator of genetical studies in many other fungi. This cycle gives rise to genetic reassortment by means other than sexual reproduction and its discovery provided a method of genetically analyzing asexual fungi. Pontecorvo also put forward the idea of the gene as a unit of function, a theory substantiated by Seymour Benzer in 1955. He made significant contributions to modern genetics in elucidating the divisibility of the gene by recombination, and in his later years in the application of parasexual techniques to mammalian cell cultures. [Image right: Aspergillus plate.] |
| António Egas Moniz | |
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Portuguese neurologist and statesman who was the founder of modern psychosurgery. In the 1920s, he pioneered the technique of cerebral angiography, enabling X-ray examination of arteries in the brain. In the 1930s, he developed the original form of prefrontal leucotomy (lobotomy), an operation for relieving severe symptoms of psychiatric illness. The operation consisted of inserting a sharp knife into the prefrontal lobe of the brain, roughly the area above and between the eyes; it required the minimum of equipment and lasted less than five minutes. For this development, he was awarded a share of the 1949 Nobel Prize for Physiology or Medicine with Walter Hess. |
| Ernest Brown | |
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Ernest (William) Brown was a British astronomer who devoted his career to the theory of the Moon's motion and constructing accurate lunar tables. His theory took account of "the gravitational action of every particle of matter which can have a sensible effect on the Moon's motion," some 1500 terms. He then determined the numerical values of the constants by analyzing 150 years of Greenwich observations, and computed tables accurate to 0.01 arcsec. After 30 years of work, Brown published his lunar tables Tables of the Motion of the Moon in 1919. In 1926 Brown published a paper in which he ascribed fluctuations in the Moon's motion to irregular changes in the Earth's period of rotation, which has subsequently proved correct. |
| Sir John Ambrose Fleming | |
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English engineer who made numerous contributions to electronics, photometry, electric measurements, and wireless telegraphy. In 1904, he discovered the one directional current effect between a positively biassed electrode, which he called the anode, and the heated filament in an evacuated glass tube; the electrons flowed from filament to anode only. Fleming called the device a diode because it contained two electrodes, the anode and the heated filament. He noted that when an alternating current was applied, only the positive halves of the waves were passed - that is, the wave was rectified (from a.c. to d.c.). It would also take a radio frequency wave and produce d.c.corresponding to the on and off of the Morse code transmitted signals. |
| Jean-Martin Charcot | |
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French founder (with Guillaume Duchenne) of modern neurology and one of France's greatest medical teachers and clinicians. Although he was a nineteenth century scientist, his influence carried on into the next century, especially in the work of some of his well-known students (Binet and Freud). In 1882, he established a neurological clinic at the Salpêtrière Hospital, Paris, that was unique in Europe. He was first to describe the degeneration of ligaments and joint surfaces due to lack of use or control, now called Charcot's joint. He did research to determine the parts of the brain responsible for specific nerve functions and discovered the importance of small arteries in cerebral hemorrhage. |
| Christian Doppler | |
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Austrian physicist who first described how the observed frequency of light and sound waves is affected by the relative motion of the source and the detector, known as the Doppler effect. In 1845, to test his hypothesis, Doppler used two sets of trumpeters: one set stationary at a train station and one set moving on an open train car, all holding the same note. As the train passed the station, it was obvious that the frequency of the notes from the two groups didn't match. Sound waves would have a higher frequency if the source was moving toward the observer and a lower freqency if the source was moving away from the observer. Edwin Hubble used the Doppler effect of light from distant stars to determine that the universe is expanding. |
| Pierre-André Latreille | |
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![]() French zoologist and Roman Catholic priest (ordained 1786) who became the father of modern entomology. During the French Revolution he was imprisoned in Bordeaux. He made the acquaintance of a physician, a fellow-prisoner, who had obtained a specimen of the rare beetle, Necrobia ruficollis. It was through this discovery that Latreille became acquainted with the naturalist, Bory de Saint-Vincent, who obtained his release. He did not share Lamarck's evolutionary views, although he worked under him from 1805 at the Muséum d'Histoire Naturelle. Latreille made the first detailed classification of crustaceans and insects. He used a "natural method" of classification combining the approaches of Linnaeus and Fabricius. [Image top right: Necrobia ruficollis] |
| John Ray | |
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Leading 17th-century English naturalist and botanist who contributed significantly to progress in taxonomy, and is often referred to as the father of natural history in Britain. He toured Europe with Francis Willoughby in search of specimens of flora and fauna. Ray was the first to classify flowering plants into monocotyledons and dicotyledons. Ray established the species as the basic taxonomic unit - his enduring legacy to botany. His major work was the three-volume Historia Plantarum (1686-1704). He also attempted to classify the animal kingdom. In 1693 he published a system based on a number of structural characters, including internal anatomy, which provided a more natural classification than those being produced by his contemporaries. |
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| NOVEMBER 29 - DEATHS | |
| Lewis Hastings Sarett | |
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American organic chemist who prepared a synthetic version of the hormone cortisone (1944) using a complicated 36-step process. He was a research scientist (1942-48) at Merck & Co., Inc. Four years later the Mayo Clinic demonstrated the efficacy of the product against rheumatoid arthritis. Cortisone also has wide-ranging applications in the treatment of allergies as well as inflammatory and neoplastic diseases. In 1949, Sarett and several collaborators initiated an alternative synthesis commencing with raw materials derivable from coal, air, lime, and water. This led to the first route independent of naturally occurring starting materials. Sarett was the 1975 recipient of the National Medal of Science.« |
| Jean Dieudonné | |
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French mathematician and educator known for his writings on abstract algebra, functional analysis, topology, and his theory of Lie groups. Dieudonné was one of the two main contributors to the Bourbaki series of texts. He began his mathematical career working on the analysis of polynomials. He worked in a wide variety of mathematical areas including general topology, topological vector spaces, algebraic geometry, invariant theory and the classical groups. |
| Vladimir Nikolayevich Ipatieff | |
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Russian-born U.S. chemist who was one of the first to investigate high-pressure catalytic reactions of hydrocarbons and who developed a process for manufacturing high-octane gasoline. While studying in Munich (1897) Ipatieff achieved the synthesis of isoprene, the basic unit of the rubber molecule. Upon return to Russia he worked particularly on the use of high-pressure catalysis and of metallic oxides as catalysts. With these techniques, he helped to establish the petrochemical industry in both pre- and post-revolutionary Russia. Before WW I, he had synthesized isooctane, and had polymerized ethylene. After moving to the U.S. (1930), Ipatieff showed how to convert low-octane gasolines into high-octane by 'cracking' hydrocarbons at high temperatures. |
| Dallas Lore Sharp | |
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American professor of English who was among the most popular nature writers of his time. His essays familiarized his readers with the natural world on their doorstep in the local woods and fields. In 1901 he published his first book, Wild Life Near Home. Rather than expansive vistas of the wilderness, Sharp wrote in the small-scale about flora and fauna of the back yard and pasture, such as the pines, persimmon, bees, chipmunks, muskrat and chick-a-dee. He urged people to take an interest in conservation, as in his bookThe Lay of the Land. Some of his books sold over one hundred thousand copies. He wrote many essays for popular magzines such as Atlantic Monthly. He died of a brain tumour with more than 20 books to his credit.« |
| Alfred Brandt | |
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German civil engineer who was primarily responsible for the successful driving of the 12.5 mile (20-km) Simplon Tunnel, largest of the great Alpine tunnels. He first saw the difficulties of tunnel construction as a young railroad engineer during the construction of the St. Gotthard Tunnel (Italy-Switzerland). That work used a pneumatic drill and blasting. Brandt designed an hydraulic drill which was used successfully to build the Arlberg Tunnel (Austria-Switzerland). Commissioned to dig the Simplon Tunnel, he innovated by driving two separate tunnels 55-ft (17-m) apart, connected by crosshatches to provide for ventilation, temperature control and a circuit for debris-removal trains. He died early in the project, from the strain of overworking himself. [Image: Simplon Tunnel during construction, model] |
| John Wyatt | |
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English inventor of machines for making files and rolling lead, with commercial support from the Birmingham inventor Lewis Paul. Wyatt invented and perfected the compound-lever weighing machine. After 1744, machines for weighing up to 5 tons were set up in several cities. He also engaged in road construction, bridge building, water-powered engines and canals. Wyatt contributed to the development of a powered machine for cotton spinning by rollers. This, first patented in 1738, was almost certainly Paul's idea, with Wyatt providing the technical skill. The principle was to draw the fibres through sets of rollers turning at different speeds. It had limited success for a time but was superseded by Richard Arkwright's water frame in the 1770s. [Image: detail from patent showing the rollers, spindle and bobbin] |
| NOVEMBER 29 - EVENTS | |
| Concorde | |
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| Animal astronaut | |
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| Underground atom bomb test | |
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| Rescue winch | |
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| Blue baby operation | |
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| Electric card dealer | |
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| Traffic signal | |
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| Edison phonograph | |
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| Steam printing | |
| Iodine discovery announced | |
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| Royal College of Physicians, Scotland | |



