| OCTOBER 8 - BIRTHS | |
| Franklin W. Stahl | |
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![]() Franklin W(illiam) Stahl is a U.S. geneticist who, in 1958, (with Matthew Meselson) elucidated the mode of replication of deoxyribonucleic acid (DNA; the gene substance) a double-stranded helix that dissociates to form two strands, each of which directs the construction of a new sister strand. They grew E. coli on media (food) that contained the heavier isotope of nitrogen-15 causing all of their DNA to be heavy. They switched the E. coli to media that contained normal nitrogen and then analyzed the DNA after each generation. After one generation, all of the DNA was medium-weight. Thus one strand of the double helix was heavy and one strand was light. After two generations, half of the DNA was medium-weight and half was normal light-weight DNA. [graphic source] |
| César Milstein | |
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Argentine immunologist who in 1984 (with Georges Köhler and Niels K. Jerne) received the Nobel Prize for Physiology or Medicine for his synthesis of monoclonal antibodies (proteins that are produced by the cells of the immune system). By fusing antibody-producing B lymphocyte cells with tumor cells that are "immortal," his lab was able to produce a "hybridoma," which could continuously synthesize antibodies. All of the antibodies produced by this single clone type of hybridoma cell were identical (monoclonal), the same as those produced by the B cell before it was fused. This technique of monoclonal antibody production, developed in 1975 with Georges Kohler, has been used extensively in the commercial development of new drugs and diagnostic tests. |
| Jens C. Skou | |
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Danish biophysicist who (with Paul D. Boyer and John E. Walker) was awarded the Nobel Prize for Chemistry in 1997 for his discovery of the enzyme called sodium-potassium-activated adenosine triphosphatase (Na+-K+ ATPase). This enzyme, which is found in the plasma membrane of animal cells, maintains the balance of sodium and potassium ions in the living cell. Skou used as experimental material finely ground crab nerve membranes. The enzyme pumps sodium out of the cell and potassium into it, thereby maintaining a high intracellular concentration of potassium and a low concentration of sodium relative to the surrounding external environment. He was first to identify an enzyme that moves substances through cell membranes, a key function of all cells. |
| Rodney Porter | |
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British biochemist who (with Gerald M. Edelman) was awarded the 1972 Nobel Prize in Physiology or Medicine for discoveries concerning the chemical structure of antibodies. As giant molecules, antibodies are difficult to study. Both scientists looked for methods to split the large molecules into well defined fragments that, it was hoped, would prove to be more easily handled. Porter found that this could be done using papain, a protein splitting enzyme. Whereas previously it had earlier been assured that the most common type of antibody would carry two identical combining sites, Porter in fact found that the molecule split into three fragments: two smaller very similar ones, both with capacity of combining with the antigen, and one larger one lacking this capacity. |
| Robert Rowe Gilruth | |
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American aerospace scientist, engineer, and a pioneer of the Mercury, Gemini, and Apollo space programs. He developed the X-1, first plane to break the sound barrier. Gilruth directed Project Mercury, the initial program for achieving manned space flight. Under his leadership, the first American astronaut orbited the Earth only a little over 3 years after NASA was created. In 1961, President Kennedy and the Congress committed the nation to a manned lunar landing within the decade. Gilruth was named the Director of the Manned Spacecraft Center and assigned the responsibility of designing and developing the spacecraft and associated equipment, planning and controlling missions, and training flight crews. He retired from NASA in 1973. |
| Harry G(ilbert) Day | |
1950 (source) |
![]() American nutritional biochemist who helped develop (with Joe Muhler and William Nebergall) the fluoride additive used in toothpaste to combat tooth decay. Proctor and Gamble (P&G) funded his research at Indiana University. In 1955, the Food and Drug administration approved stannous fluoride for use in toothpaste. P&G introducedCresttoothpaste in Jan 1956 with this ingredient, which they called fluoristan. The patent was held by Indiana University, and P&G paid royalties for its use. In his career, Day's research evaluated the health aspects of food ingredients, principles of food safety, and nutrition including the nutritional requirements of phosphorus, zinc, fluoride, boron and iron. [Image right: (source)]« |
| Ernst Kretschmer | |
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German psychiatrist who attempted to correlate body build and physical constitution with personality characteristics and mental illness. Kretschmer analyzed over 4,000 criminal cases using his 3 body type model: (1) leptosome or asthenic [tall and thin], (2) athletic [well developed muscles], and (3) pyknic [short and fat]. His conclusion was that were is a greater number of violent criminals who correspond to the athletic type, while the asthenic are more likely to be involved in petty theft and fraud. Finally, Kretschmer found that the pyknic tended toward crimes involving deception and fraud but were also sometimes involved in violent crimes. |
| Otto Warburg | |
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Otto Heinrich Warburg was a German biochemist awarded the Nobel Prize for Physiology or Medicine in 1931 for his research on cellular respiration, the process by which substances directly supplied to cells or stored in them are broken down into simpler components while using up oxygen. It is by this process that the energy required for other vital processes is made available to the cells in a form capable of immediate utilization. He devised a manometer for this research, enabling him to study the action of respiratory enzymes and poisons in detail. |
| Ejnar Hertzsprung | |
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Danish astronomer who classified types of stars by relating their surface temperature (or colour) to their absolute brightness. A few years later Russell illustrated this relationship graphically in what is now known as the Hertzsprung-Russell diagram, which has become fundamental to the study of stellar evolution. In 1913 he established the luminosity scale of Cepheid variable stars. |
| Kristine Bonnevie | |
(a.k.a. Christine Bonnevie) Norwegian zoologist and geneticist who in 1911 became the first woman admitted to the Norwegian Academy of Science and Letters. In 1912, the University of Oslo was appointed her as Norway's first female professor. One of her students in the 1930's was Thor Heyerdahl who later organized and led the famous Kon-Tiki (1947) and Ra (1969-70) transoceanic scientific expeditions. |
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| James Frank Duryea | |
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![]() James Frank Duryea was an American inventor who with his brother Charles Duryea built the first automobile with multiple copies manufactured in the U.S. On 28 Nov 1895, Frank drove their car to win first prize in the first American Automobile Race in Chicago, held by the Chicago Times-Herald. At 8:55 am, six "motocycles" left Chicago's Jackson Park for a 54 mile race to Evanston, Illinois and back through the snow. Duryeas' No.5 took just over 10 hr (ave. 7.3 mph). Early in 1896, the Duryeas manufactured 13 copies of the car. Frank developed the "Stevens-Duryea," an expensive limousine, which remained in production into the 1920s. The brothers are recognised as "Fathers of the American Automobile Industry."« [Image: the Duryea automobile of 1893.] |
| Henry-Louis Le Chatelier | |
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French chemist who is best known for the principle of Le Chatelier, which makes it possible to predict the effect a change of conditions (temperature, pressure, and concentration of reaction components) will have on a chemical reaction. This principle proved invaluable in the chemical industry for developing the most efficient chemical processes. Fritz Haber successfully utilized it in his process for the production of ammonia. Le Chatelier's interests began in metallurgy, cements, ceramics, and glass, and his studies of flames led him to study heat and its measurement. Of several contributions to thermometry, his most important was the first successful design of a platinum and rhodium thermocouple for measuring high temperatures (1887). |
| Jean Perronet | |
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Jean(-Rodolphe) Perronet was a French civil engineer renowned for his stone-arch bridges, especially the Pont de la Concorde, Paris. During construction of a bridge at Mantes in 1763, Perronet made the discovery that the horizontal thrust of a series of elliptical arches was passed along to the abutments at the ends of the bridge. Thus he was able to build extremely flat arches that were supported during construction by timbering (falsework) and mounted on very slender piers, which widened the waterway for navigation and reduced scour from the current. |
| OCTOBER 8 - DEATHS | |
| Robert Emden | |
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Swiss astrophysicist and mathematician who wrote Gaskugeln (Gas Spheres, 1907), giving a mathematical model of stellar structure as the expansion and compression of gas spheres, wherein the forces of gravity and gas pressure are in equilibrium. He expanded on earlier work by J. H. Lane (1869) and A. Ritter (1878-83) who first derived equations describing stars as gaseous chemical, spherical bodies held together by their own gravity and obeying the known gas laws of thermodynamics. For four decades, the Lane-Emden equation was the foundation of theoretical work on the structure of stars: their central temperatures and pressures, masses, and equilibria. Emden also devised a hypothesis, no longer taken seriously, to explain sunspots.« |
| Joseph Déchelette | |
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![]() French archaeologist who was an authority on Gallo-Roman and Celtic coins. He wrote Le Manuel d'archéologie préhistorique, celtique et gallo-romaine (1908-14) about the pre-history of France. With his uncle, J.-G. Bulliot, Déchelette excavated Gallic ruins of Bibracte at Mont Beuvray, the only oppidum (a fortified city) in Gaul where the excavations have been sufficiently extended to give an idea of what a Gallic fortified city looked like in the first century B.C. He described his findings in L'Oppidum de Bibracte (1903) which retraces the history of this oppidum and describes what the organisation of the city was: the craft area, the residential area (druids and knights' houses), the place of worship and the wide market place. [Image right: Beuvray relic (source) ] |
| Clemens Alexander Winkler | |
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German chemist who discovered the element germanium (1886). He had a background in managing a cobalt glassworks and then on the faculty of the Freiberg School of Mining. Early in his career, he developed new techniques for industrial gas analysis and developed the Winkler gas burette. When, having been asked by the Freiberg Academy of Mining to analyze the mineral argyrodite (a silver sulphide ore), he found that all the known elements it contained amounted to only 93% of its weight. After spending four months tracking down and isolating the remaining 7%, he found the new element he called germanium, for Germany. This turned out to be the third of the elements (eka-silicon) predicted by Dmitry I. Mendeleyev in 1871.« |
| Christian Longomontanus | |
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Byname of Christian Severin, a Danish astronomer and astrologer who is best known for his association with, and published support for, Tycho Brahe. He became the first professor of astronomy at the University of Copenhagen, and in 1610 he received funds for instruments and he probably constructed a small observatory at his home. Longomontanus used Tycho's data to compile the Astronomia danica (1622), an exposition of the Tychonic system, which holds that the Sun revolves around the Earth and the other planets revolve around the Sun. He began the construction of the Copenhagen Observatory in 1632, but died before its completion. |
| OCTOBER 8 - EVENTS | |
| Post Office Tower | |
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| Heart pacemaker | |
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| Permanent wave | |
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| LA-SF telegraph | |
| Erie Canal | |
| Congreve rockets | |
| Kepler's nova | |
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