| NOVEMBER 30 - BIRTHS | |
| Andrew V. Schally | |
(source) |
Polish-born American endocrinologist and corecipient, with Roger Guillemin and Rosalyn Yalow, of the 1977 Nobel Prize for Physiology or Medicine. Schally fled Poland with his family in 1939. Schally became a U.S. citizen in 1962. He became senior medical investigator with the Veterans Administration in 1973. He was noted for isolating and synthesizing three hormones that are produced by the region of the brain known as the hypothalamus; these hormones control the activities of other hormone- producing glands. These accomplishments were the synthesis of TRH (thyrotropin-releasing hormone), the isolation and synthesis of LH-RH (luteinizing hormone-releasing hormone), and studies of the action of somatostatin. |
| Henry Taube | |
1983(source) |
Canadian-born American chemist who in 1983 won the Nobel Prize for Chemistry for his extensive research into the properties and reactions of dissolved inorganic substances, particularly oxidation-reduction processes involving the ions of metallic elements. Metals often form complexes, in which other atoms cluster around the metal atom, transfering and sharing electrons among themselves to bind together. Taube discovered that during a reaction, a temporary "bridge" of atoms often forms between metal atoms. He studied the electron transfer across this bridge, speeding up reactions that would otherwise happen only slowly or not at all. His ideas are relevant beyond his own field of study, for example, in biochemical processes such as respiration. |
| Andrew J(ackson) Moyer | |
(source) |
American microbiologist who invented a method for mass-producing the antibiotic penicillin. While working for the US Agriculture Department laboratory (1940-57), he discovered a technique for antibiotic fermentation using continuous shaking of a culture broth of corn steep liquor (a by-product of the corn starch manufacturing process) and lactose. His method improved on prior methods producing 2 to 8 Oxford units/ml of broth, to in excess of 200 Oxford units/ml. By making possible the large-scale production of penicillin, the process is credited with saving thousands of lives during World War II. Corn steep liquor was adopted for other commercial fermentation processes making many other antibiotics, and the method is still in use today.« |
| Cyrus West Field | |
(source) |
American entrepreneur who promoted the first transatlantic telephone cable. In 1856, he helped establish the Atlantic Telegraph Company. He obtained charters from the British and American governments, and arranged financial backers in New York and London. For technical services he enlisted British engineer Charles Tilston Bright and William Thomson (later Lord Kelvin). Laying the first cable was completed 5 Aug 1858, but shortly failed. Field persisted, and on 27 Jul 1866, an improved cable was laid. Field had built his personal fortune of $250,000 from a paper business (1841-53). Later, he invested in the New York Elevated Railroad Co. (1877-80), and the Wabash Railroad. By late in life, he had lost much of his fortune.« |
| Edgar Douglas Adrian | |
(source) |
(Baron) English electrophysiologist who is one of the founders of modern neurophysiology. He shared (with Sir Charles Sherrington) the Nobel Prize for Physiology or Medicine in 1932 for "for their discoveries regarding the functions of neurons." While a student under Keith Lucas at Cambridge, Adrian discovered the "all-or-none" phenomenon (the relation between stimulus intensity and muscle-fibre contraction) in muscle-nerve preparations. During a career at Cambridge he developed the capillary electrometer to measure minute signals from nerve fibres and discovered the nature of coding of the motor and sensory impulses in afferent and efferent fibres. In the early 1930s, he advanced concepts of electro-encephalography, research on electrical brain waves. |
| Nils Dalén | |
(source) |
Swedish engineer who won the Nobel Prize for Physics in 1912 for his invention of the automatic sun valve, or Solventil, which regulates a gaslight source by the action of sunlight, turning it off at dawn and on at dusk or at other periods of darkness. It rapidly came into worldwide use for buoys and unmanned lighthouses. While recovering from an accident, convalescing at home, he noticed how much time his wife spent caring for their wood-burning stove. He decided to invent a more efficient and cost-effective stove. In 1922, Dalen's Amalgamated Gas Accumulator Co. patented his design and put the first AGA stoves into production. These stoves produced a radiant heat that kept the kitchen warm. The AGA remains popular today. |
| Sir Jagadis Chandra Bose | |
(source) |
Indian plant physiologist and physicist whose invention of highly sensitive instruments for the detection of minute responses by living organisms to external stimuli enabled him to anticipate the parallelism between animal and plant tissues noted by later biophysicists. |
| Sir William Henry Flower | |
(source) |
British zoologist who made significant contributions to comparative anatomy and clarification of the classification of mammals, including carnivores (1869), rhinocerosces (1875), and edentates (1882). He was superintendent, and subsequently followed Sir Richard Owen as director of Natural History Departments of the British Museum of Natural History (1884-98). Flower's innovations in museum displays greatly improved their educational value to the public. His main research interest dealt with marsupials, primates and especially whales, through which he was the first to demonstrate that lemurs are primates. Further, in thorough anthropological studies, he recorded detailed measurements of over 1,300 human skulls. |
| Nathanael Pringsheim | |
algae (source) |
German botanist who was one of the founders of the science of algology (study of algae). He made important discoveries in the morphology and physiology of plants, especially in the fields of reproduction and evolution. Pringsheim's observation of the formation of plant cells provided support for the belief, opposed by the German botanist Matthias Jakob Schleiden, that cells arise only by division of pre-existing cells. In 1868 Pringsheim and Julius von Sachs were the first to describe the specialized bodies in the cell cytoplasm called plastids. Pringsheim also was the first to demonstrate a case of apospory, (production of a sexual generation from an asexual generation without the intervention of spores), in the Thallophyta (e.g., algae, fungi). |
| Johann Lukas Schönlein | |
1860 (source) |
German physician whose attempts to establish medicine as a natural science helped create modern methods for the teaching and practice of clinical medicine. Schönlein was the first to use the microscope in conjunction with urine and blood analyses to diagnose disease. He coined the term hemophilia (1828), was the first to describe purpura rheumatica (1837, hence called Schönlein's disease) and discovered fungus causing favus (1839). |
| Ernst Florens Friedrich Chladni | |
(source) |
German physicist, known as the "father of acoustics" for his mathematical investigations of sound waves. Chladni figures, seen when thin plates covered in sand at set in vibration, are complex patterns of vibration with nodal lines that remain stationary and retain sand. He demonstrated these to an audience of scientists in 1809. He measured the speed of sound in various gases by determining the pitch of the note of an organ pipe filled with different gases. To determine the speed of sound in solids, Chladni, used analysis of the nodal pattern in standing-wave vibrations in long rods. He performed on the euphonium, an instrument he invented, made of glass and steel bars vibrated by rubbing with a moistened finger. He also investigated meteorites. |
| Ebenezer Kinnersley | |
(source) |
English-born American experimenter and inventor who investigated electricity. In 1748 Kinnersley demonstrated that the electric fluid actually passed through water, using a 10-ft long trough of water. In 1751, as one of the earliest popularizers of science, he began delivering lectures on "The Newly Discovered Electrical Fire." His experiments discovered the difference between the electricity that was produced by the glass and sulphur globes, which he communicated to Benjamin Franklin at Philadelphia, since they showed beyond a doubt that the positive and negative theory was correct. He also sought ways to protect buildings from lightning, invented an electric thermometer (c. 1755), and demonstrated that electricity can produce heat.« [Image: simplified version of Kinnersley's electrical air thermometer in which colored water in the airtight cylinder pushed water up the capillary tube when sparking between electrodes heated and expanded the air.] |
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| NOVEMBER 30 - DEATHS | |
| Robert A. Swanson | |
(source) |
American chemist who, at age 29, cofounded Genentech, Inc. (1976), a research-based company that pioneered the biotechnology industry. His cofounder, distinguished biochemist, Herbert Boyer, had developed one of the key techniques that opened up the possibility of the transfer of genes from one organism to another. Boyer was a pioneer using restriction enzymes to snip segments of DNA out of cells. In 1977, Genentech began mass- producing their first human protein by splicing a gene into bacteria. In 1978, Genentech created the first drug produced by genetic engineering, human-type insulin. It was also the first biotechnology company to sell its own drug, human growth hormone. Swanson died after a long battle against brain cancer. |
| Alfonso Caso y Andrade | |
(source) |
Mexican archaeologist and government official who explored the early Oaxacan cultures and is best remembered for his excavation of Tomb Seven at Monte Albán, the earliest-known North American necropolis. His first book, El mapa de Teozacoalco, (1949), is a key to Mixtec history. For 40 years, he studied prehispanic writing, striving to decipher the forgotten inscriptions. His most famous work, Kings and Kingdoms of the Mixteca, was finished only a few days before he died in 1970. |
| Casimir Funk | |
(source) |
Polish-American biochemist who coined the term "vitamine." In 1912, as had previously been proposed by Sir Frederick Hopkins, Funk pusued the idea that diseases such as beriberi, scurvy, rickets and pellagra were caused by lack of vital substances in the diet. His investigation of Eijkman's anti-beriberi factor had shown that it was an amine (an organic substance wih molecules containing the -NH2 amine group). Funk assumed (though incorrectly) that all similar substances were also amines, and he named such factors vitamines ("life-amines"). When later it was discovered that not all the factors were amines, the spelling of the word was changed to "vitamin." Funk isolated nicotinic acid from rice polishing, later used against pellagra by Warburgh and Elvehjem. |
| John Mercer | |
(source) |
English chemist and industrialist who invented the mercerisation process for treating cotton which is still in use today and was a pioneer in colour photography. From age 16, and throughout his life, he investigated and developed chemical textile dyes. Late in his life, in 1844, he found that when cotton is treated with caustic chemicals, it became thicker and shorter - thereby stronger and shrink-resistant. Further, the cotton was more easily dyed, needed 30% less dye, more absorbant, and could be given an attractive silk-like lustre. He called his process mercerisation and patented it in 1850. Mercerisation was applied to many other materials, such as parchment and woolen fabric, and remains an important part of the cotton finishing process today. |
| Germain Henri Hess | |
(source) |
Swiss-born Russian chemist whose studies of heat in chemical reactions formed the foundation of thermochemistry. He formulated an empirical law, Hess's law of constant heat summation (1840), which states that the heat evolved or absorbed in a chemical process is the same whether the process takes place in one or in several steps. It is explained by thermodynamic theory, which holds that enthalpy is a state function. Chemists have made great use of the law of Hess in establishing the heats of formation of compounds which are not easily formed from their constituent elements. His early investigations concerned minerals and the natural gas found near Baku, and he also discovered the oxidation of sugars to yield saccharic acid. |
| John Dollond | |
(source) |
British maker of optical and astronomical instruments who developed (1758) and patented an achromatic (non- colour- distorting) refracting telescope and a practical heliometer, a telescope used to measure the Sun's diameter and the angles between celestial bodies. In the 1730's, Chester More Hall, an attorney with an interest in telescopes, first discovered that flint glass appeared to have a greater color dispersion than crown glass did at the same magnifications. Hall reasoned that if he cemented the concave face of a flint glass lens to the convex face of a crown glass lens, he could remove the dispersion properties (and thus, chromatic aberration) from both lenses simultaneously. Dollond learned of the technique in the 1750's and developed it. |
| Marcello Malpighi | |
(source) |
Italian physician and biologist who, in developing experimental methods to study living things, founded the science of microscopic anatomy. After Malpighi's researches, microscopic anatomy became a prerequisite for advances in the fields of physiology, embryology, and practical medicine. Drawing on the work of William Harvey, he studied the circulatory and respiratory systems of all living things and arranged them in a hierarchical system, beginning with plants, above which were insects, then fishes, then the mammals, then man. He was one of the first scientists to study such anatomical structures as the lungs, kidneys, spleen, brain, tongue, and skin at the microscopic level. |
| (Francesco) Bonaventura Cavalieri | |
(source) |
Italian mathematician who made developments in geometry that were precursors to integral calculus. Cavalieri's theory of indivisibles, presented in his Geometria indivisibilis continuorum nova (1635) was a development of Archimedes' method of exhaustion incorporating Kepler's theory of infinitesimally small geometric quantities. The area and volume of various geometric figures can easily be found with this method. He was largely responsible for introducing logarithms as a computational tool in Italy through his book Directorium Generale Uranometricum, including logarithms of trigonometric functions for astronomers. He also wrote on optics and astronomy. Galileo thought highly of his writing, and corresponded with him. |
| William Gilbert | |
(source) |
English scientist, the "father of electrical studies" and a pioneer researcher into magnetism, who spent years investigating magnetic and electrical attractions. Gilbert coined the names of electric attraction, electric force, and magnetic pole. He became the most distinguished man of science in England during the reign of Queen Elizabeth I. Noting that a compass needle not only points north and south, but also dips downward, he thought the Earth acts like a bar magnet. Like Copernicus, he believed the Earth rotates on its axis, and that the fixed stars were not all at the same distance from the earth. Gilbert thought it was a form of magnetism that held planets in their orbits. |
| NOVEMBER 30 - EVENTS | |
| Artificial heart | |
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| Meteorite strikes woman | |
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| Crystal Palace fire | |
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| Transatlantic radio photo fax | |
| Aluminium conductor | |
| Black American patent | |
(USPTO) |
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| A.C. power plant | |
| Oat-crushing machine | |
(USPTO) |
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| Black American patent | |
(USPTO) |
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| First U.S. river tunnel | |
(source) |
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| Mason jar | |
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| First free air meteorological observations | |
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| Galileo's moon drawing | |
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Note: Sale of first concentrated milk, often seen stated for 30 Nov 1950, should be 2 Nov 1950. |
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