Synthesis Quotes (11)

Chemistry affords two general methods of determining the constituent principles of bodies, the method of analysis, and that of synthesis. When, for instance, by combining water with alkohol, we form the species of liquor called, in commercial language, brandy or spirit of wine, we certainly have a right to conclude, that brandy, or spirit of wine, is composed of alkohol combined with water. We can produce the same result by the analytical method; and in general it ought to be considered as a principle in chemical science, never to rest satisfied without both these species of proofs. We have this advantage in the analysis of atmospherical air, being able both to decompound it, and to form it a new in the most satisfactory manner.
Elements of Chemistry (1790), trans. R. Kerr, 33.
See also:  |  Air (25)  |  Alcohol (4)  |  Analysis (37)  |  Atmosphere (18)  |  Chemistry (87)  |  Conclusion (24)  |  Decomposition (6)  |  Language (38)  |  Proof (59)  |  Wine (5)

Chemistry is the study of material transformations. Yet a knowledge of the rate, or time dependence, of chemical change is of critical importance for the successful synthesis of new materials and for the utilization of the energy generated by a reaction. During the past century it has become clear that all macroscopic chemical processes consist of many elementary chemical reactions that are themselves simply a series of encounters between atomic or molecular species. In order to understand the time dependence of chemical reactions, chemical kineticists have traditionally focused on sorting out all of the elementary chemical reactions involved in a macroscopic chemical process and determining their respective rates.
'Molecular Beam Studies of Elementary Chemical Processes', Nobel Lecture, 8 Dec 1986. In Nobel Lectures: Chemistry 1981-1990 (1992), 320.
See also:  |  Chemistry (87)  |  Matter (61)  |  Reaction (23)  |  Transformation (3)

Evolution: The Modern Synthesis.
Book title
Evolution: The Modern Synthesis (1942).
See also:  |  Evolution (229)  |  Modern (2)

I have no fault to find with those who teach geometry. That science is the only one which has not produced sects; it is founded on analysis and on synthesis and on the calculus; it does not occupy itself with the probable truth; moreover it has the same method in every country.
In Oeuvres de Frederic Le Grand edited by J.D.E. Preuss (1849), Vol. 7, 100. In Robert Édouard Moritz, Memorabilia Mathematica (1917), 310.
See also:  |  Analysis (37)  |  Calculus (12)  |  Geometry (38)  |  Method (12)  |  Truth (241)

It is a very strange thing to reflect that but for the invention of Professor Haber the Germans could not have continued the War after their original stack of nitrates was exhausted. The invention of this single man has enabled them, utilising the interval in which their accumulations were used up, not only to maintain an almost unlimited supply of explosives for all purposes, but to provide amply for the needs of agriculture in chemical manures. It is a remarkable fact, and shows on what obscure and accidental incidents the fortunes of possible the whole world may turn in these days of scientific discovery.
[During World War I, Fritz Haber and Karl Bosch invented a large scale process to cause the direct combination of hydrogen and nitrogen gases to chemically synthesize ammonia, thus providing a replacement for sodium nitrate in the manufacture of explosives and fertilizers.]
Parliamentary debate (25 Apr 1918). In Winston Churchill, Richard Langworth (ed.), Churchill by Himself: The Definitive Collection of Quotations‎ (2008), 469. by Winston Churchill, Richard Langworth
See also:  |  Ammonia (3)  |  Discovery (166)  |  Explosive (4)  |  Fertilizer (8)  |  Industrial Chemistry (3)  |  Invention (84)  |  Reaction (23)  |  War (51)

It is, I believe, justifiable to make the generalization that anything an organic chemist can synthesize can be made without him. All he does is increase the probability that given reactions will 'go.' So it is quite reasonable to assume that given sufficient time and proper conditions, nucleotides, amino acids, proteins, and nucleic acids will arise by reactions that, though less probable, are as inevitable as those by which the organic chemist fulfills his predictions. So why not self-duplicating virus-like systems capable of further evolution?
The Place of Genetics in Modern Biology (1959),18.
See also:  |  Amino Acid (4)  |  DNA (28)  |  Evolution (229)  |  Protein (19)  |  Reaction (23)

Life is not found in atoms or molecules or genes as such, but in organization; not in symbiosis but in synthesis.
'Cell and Protoplasm Concepts: Historical Account', The Cell and the Protoplasm: Publication of the American Association of Science, 1940, Number 114, 18.
See also:  |  Atom (85)  |  Gene (29)  |  Life (155)  |  Molecule (39)  |  Organization (10)

More about the selection theory: Jerne meant that the Socratic idea of learning was a fitting analogy for 'the logical basis of the selective theories of antibody formation': Can the truth (the capability to synthesize an antibody) be learned? If so, it must be assumed not to pre-exist; to be learned, it must be acquired. We are thus confronted with the difficulty to which Socrates calls attention in Meno [ ... ] namely, that it makes as little sense to search for what one does not know as to search for what one knows; what one knows, one cannot search for, since one knows it already, and what one does not know, one cannot search for, since one does not even know what to search for. Socrates resolves this difficulty by postulating that learning is nothing but recollection. The truth (the capability to synthesize an antibody) cannot be brought in, but was already inherent.
'The Natural Selection Theory', in John Cairns, Gunther S. Stent, and James D. Watson (eds.) Phage and the Origins of Molecular Biology (1966), 301.
See also:  |  Analogy (8)  |  Antibody (2)  |  Inherent (2)  |  Knowledge (330)  |  Learning (43)  |  Search (10)  |  Selection (3)  |  Socrates (3)  |  Truth (241)

Once a molecule is asymmetric, its extension proceeds also in an asymmetrical sense. This concept completely eliminates the difference between natural and artificial synthesis. The advance of science has removed the last chemical hiding place for the once so highly esteemed vis vitalis.
‘Synthesen in der Zuckergruppe', Berichte der deutschen Chemischen Gesellschaft, 1894, 27, 3189.
See also:  |  Life (155)  |  Molecule (39)  |  Stereochemistry (2)

Science is spectral analysis. Art is light synthesis.
Pro domo et Mundo, (1912) Chap. 4. In 'Riddles and Solutions', Half-Truths and One-And-A-Half-Truths: Selected Aphorisms, editted by Harry Zohn (1976), 47.
See also:  |  Analysis (37)  |  Art And Science (17)  |  Light (39)  |  Spectrum (6)

Since many cases are known in which the specificities of antigens and enzymes appear to bear a direct relation to gene specificities, it seems reasonable to suppose that the gene's primary and possibly sole function is in directing the final configurations of protein molecules.
Assuming that each specific protein of the organism has its unique configuration copied from that of a gene, it follows that every enzyme whose specificity depends on a protein should be subject to modification or inactivation through gene mutation. This would, of course, mean that the reaction normally catalyzed by the enzyme in question would either have its rate or products modified or be blocked entirely.
Such a view does not mean that genes directly 'make' proteins. Regardless of precisely how proteins are synthesized, and from what component parts, these parts must themselves be synthesized by reactions which are enzymatically catalyzed and which in turn depend on the functioning of many genes. Thus in the synthesis of a single protein molecule, probably at least several hundred different genes contribute. But the final molecule corresponds to only one of them and this is the gene we visualize as being in primary control.
'Genetics and Metabolism in Neurospora', Physiological Reviews, 1945, 25, 660.
See also:  |  Enzyme (8)  |  Gene (29)  |  Genetics (56)  |  Protein (19)

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