A game is on, at the other end of this infinite distance, and heads or tails will turn up. What will you wager? According to reason you cannot leave either; according to reason you cannot leave either undone... Yes, but wager you must; there is no option, you have embarked on it. So which will you have. Come. Since you must choose, let us see what concerns you least. You have two things to lose: truth and good, and two things to stake: your reason and your will, your knowledge and your happiness. And your nature has two things to shun: error and misery. Your reason does not suffer by your choosing one more than the other, for you must choose. That is one point cleared. But your happiness? Let us weigh gain and loss in calling heads that God is. Reckon these two chances: if you win, you win all; if you lose, you lose naught. Then do not hesitate, wager that He is.

Disease is largely a removable evil. It continues to afflict humanity, not only because of incomplete knowledge of its causes and lack of individual and public hygiene, but also because it is extensively fostered by harsh economic and industrial conditions and by wretched housing in congested communities. ... The reduction of the death rate is the principal statistical expression and index of human social progress. It means the saving and lengthening of lives of thousands of citizens, the extension of the vigorous working period well into old age, and the prevention of inefficiency, misery, and suffering. These advances can be made by organized social effort. Public health is purchasable. (1911)

If any student comes to me and says he wants to be useful to mankind and go into research to alleviate human suffering, I advise him to go into charity instead. Research wants real egotists who seek their own pleasure and satisfaction, but find it in solving the puzzles of nature.

It is a curious and painful fact that almost all the completely futile treatments that have been believed in during the long history of medical folly have been such as caused acute suffering to the patient. When anesthetics were discovered, pious people considered them an attempt to evade the will of God. It was pointed out, however, that when God extracted Adam's rib He put him into a deep sleep. This proved that anesthetics are all right for men; women, however, ought to suffer, because of the curse of Eve.

Knowledge is like a knife. In the hands of a well-balanced adult it is an instrument for good of inestimable value; but in the hands of a child, an idiot, a criminal, a drunkard or an insane man, it may cause havoc, misery, suffering and crime. Science and religion have this in common, that their noble aims, their power for good, have often, with wrong men, deteriorated into a boomerang to the human race.

Mainstream biology may be suffering from what I call 'Physics envy' in aiming to reduce life to nothing but well known, typically Newtonian principles of physics and chemistry.

Our contemporary culture, primed by population growth and driven by technology, has created problems of environmental degradation that directly affect all of our senses: noise, odors and toxins which bring physical pain and suffering, and ugliness, barrenness, and homogeneity of experience which bring emotional and psychological suffering and emptiness. In short, we are jeopardizing our human qualities by pursuing technology as an end rather than a means. Too often we have failed to ask two necessary questions: First, what human purpose will a given technology or development serve? Second, what human and environmental effects will it have?

Pathology, probably more than any other branch of science, suffers from heroes and hero-worship. Rudolf Virchow has been its archangel and William Welch its John the Baptist, while Paracelsus and Cohnheim have been relegated to the roles of Lucifer and Beelzebub. ... Actually, there are no heroes in Pathology—all of the great thoughts permitting advance have been borrowed from other fields, and the renaissance of pathology stems not from pathology itself but from the philosophers Kant and Goethe.

Physical misery is great everywhere out here [Africa]. Are we justified in shutting our eyes and ignoring it because our European newspapers tell us nothing about it? We civilised people have been spoilt. If any one of us is ill the doctor comes at once. Is an operation necessary, the door of some hospital or other opens to us immediately. But let every one reflect on the meaning of the fact that out here millions and millions live without help or hope of it. Every day thousands and thousands endure the most terrible sufferings, though medical science could avert them. Every day there prevails in many and many a far-off hut a despair which we could banish. Will each of my readers think what the last ten years of his family history would have been if they had been passed without medical or surgical help of any sort? It is time that we should wake from slumber and face our responsibilities!

Suffering isn't ennobling, recovery is.

The best class of scientific mind is the same as the best class of business mind. The great desideratum in either case is to know how much evidence is enough to warrant action. It is as unbusiness-like to want too much evidence before buying or selling as to be content with too little. The same kind of qualities are wanted in either case. The difference is that if the business man makes a mistake, he commonly has to suffer for it, whereas it is rarely that scientific blundering, so long as it is confined to theory, entails loss on the blunderer. On the contrary it very often brings him fame, money and a pension. Hence the business man, if he is a good one, will take greater care not to overdo or underdo things than the scientific man can reasonably be expected to take.

The men you see waiting in the lobbies of doctors' offices are, in a vast majority of cases, suffering through poisoning caused by an excess of food.

The primary rocks, ... I regard as the deposits of a period in which the earth's crust had sufficiently cooled down to permit the existence of a sea, with the necessary denuding agencies,—waves and currents,—and, in consequence, of deposition also; but in which the internal heat acted so near the surface, that whatever was deposited came, matter of course, to be metamorphosed into semi-plutonic forms, that retained only the stratification. I dare not speak of the scenery of the period. We may imagine, however, a dark atmosphere of steam and vapour, which for age after age conceals the face of the sun, and through which the light of moon or star never penetrates; oceans of thermal water heated in a thousand centres to the boiling point; low, half-molten islands, dim through the log, and scarce more fixed than the waves themselves, that heave and tremble under the impulsions of the igneous agencies; roaring geysers, that ever and anon throw up their intermittent jets of boiling fluid, vapour, and thick steam, from these tremulous lands; and, in the dim outskirts of the scene, the red gleam of fire, shot forth from yawning cracks and deep chasms, and that bears aloft fragments of molten rock and clouds of ashes. But should we continue to linger amid a scene so featureless and wild, or venture adown some yawning opening into the abyss beneath, where all is fiery and yet dark,—a solitary hell, without suffering or sin,—we would do well to commit ourselves to the guidance of a living poet of the true faculty,—Thomas Aird and see with his eyes.

The prime goal is to alleviate suffering, and not to prolong life. And if your treatment does not alleviate suffering, but only prolongs life, that treatment should be stopped.

The sciences have sworn among themselves an inviolable partnership; it is almost impossible to separate them, for they would rather suffer than be torn apart; and if anyone persists in doing so, he gets for his trouble only imperfect and confused fragments. Yet they do not arrive all together, but they hold each other by the hand so that they follow one another in a natural order which it is dangerous to change, because they refuse to enter in any other way where they are called. ...

We have reason not to be afraid of the machine, for there is always constructive change, the enemy of machines, making them change to fit new conditions.
We suffer not from overproduction but from undercirculation. You have heard of technocracy. I wish I had those fellows for my competitors. I'd like to take the automobile it is said they predicted could be made now that would last fifty years. Even if never used, this automobile would not be worth anything except to a junkman in ten years, because of the changes in men's tastes and ideas. This desire for change is an inherent quality in human nature, so that the present generation must not try to crystallize the needs of the future ones.
We have been measuring too much in terms of the dollar. What we should do is think in terms of useful materials—things that will be of value to us in our daily life.

You bring me the deepest joy that can be felt by a man whose invincible belief is that Science and Peace will triumph over Ignorance and War, that nations will unite, not to destroy, but to build, and that the future will belong to those who will have done most for suffering humanity.