...the source of all great mathematics is the special case, the concrete example. It is frequent in mathematics that every instance of a concept of seemingly generality is, in essence, the same as a small and concrete special case.

As for the search for truth, I know from my own painful searching, with its many blind alleys, how hard it is to take a reliable step, be it ever so small, towards the understanding of that which is truly significant.

Fear of something is at the root of hate for others and hate within will eventually destroy the hater. Keep your thoughts free from hate, and you will have no fear from those who hate you. ...
David, though small, was filled with truth, right thinking and good will for others. Goliath represents one who let fear into his heart, and it stayed there long enough to grow into hate for others.

For a stone, when it is examined, will be found a mountain in miniature. The fineness of Nature's work is so great, that, into a single block, a foot or two in diameter, she can compress as many changes of form and structure, on a small scale, as she needs for her mountains on a large one; and, taking moss for forests, and grains of crystal for crags, the surface of a stone, in by far the plurality of instances, is more interesting than the surface of an ordinary hill; more fantastic in form and incomparably richer in colour—the last quality being, in fact, so noble in most stones of good birth (that is to say, fallen from the crystalline mountain ranges).

I do not understand modern physics at all, but my colleagues who know a lot about the physics of very small things, like the particles in atoms, or very large things, like the universe, seem to be running into one queerness after another, from puzzle to puzzle.

I have always found small mammals enough like ourselves to feel that I could understand what their lives would be like, and yet different enough to make it a sort of adventure and exploration to see what they were doing.

In summary, very large populations may differentiate rapidly, but their sustained evolution will be at moderate or slow rates and will be mainly adaptive. Populations of intermediate size provide the best conditions for sustained progressive and branching evolution, adaptive in its main lines, but accompanied by inadaptive fluctuations, especially in characters of little selective importance. Small populations will be virtually incapable of differentiation or branching and will often be dominated by random inadaptive trends and peculiarly liable to extinction, but will be capable of the most rapid evolution as long as this is not cut short by extinction.

In the final analysis, our most basic common link is that we all inhabit this small planet. We all breathe the same air. We all cherish our children's future. And we are all mortal.

It is one of the triumphs of human wit ... to conquer by humility and submissiveness ... to make oneself small in order to appear great ... such ... are often the expedients of the neurotic.

My picture of the world is drawn in perspective and not like a model to scale. The foreground is occupied by human beings and the stars are all as small as three-penny bits. I don't really believe in astronomy, except as a complicated description of part of the course of human and possibly animal sensation. I apply my perspective not merely to space but also to time. In time the world will cool and everything will die; but that is a long time off still and its present value at compound discount is almost nothing.

Nature has but one plan of operation, invariably the same in the smallest things as well as in the largest, and so often do we see the smallest masses selected for use in Nature, that even enormous ones are built up solely by fitting these together. Indeed, all Nature's efforts are devoted to uniting the smallest parts of our bodies in such a way that all things whatsoever, however diverse they may be, which coalesce in the structure of living things construct the parts by means of a sort of compendium.

Nature, ... in order to carry out the marvelous operations [that occur] in animals and plants has been pleased to construct their organized bodies with a very large number of machines, which are of necessity made up of extremely minute parts so shaped and situated as to form a marvelous organ, the structure and composition of which are usually invisible to the naked eye without the aid of a microscope. ... Just as Nature deserves praise and admiration for making machines so small, so too the physician who observes them to the best of his ability is worthy of praise, not blame, for he must also correct and repair these machines as well as he can every time they get out of order.

Never doubt that a small group of thoughtful, committed citizens can change the world; indeed, it is the only thing that ever has.

Nothing is really small; whoever is open to the deep penetration of nature knows this.

Quantum theory thus reveals a basic oneness of the universe. It shows that we cannot decompose the world into independently existing smallest units. As we penetrate into matter, nature does not show us any isolated “building blocks,” but rather appears as a complicated web of relations between the various parts of the whole. These relations always include the observer in an essential way. The human observer constitute the final link in the chain of observational processes, and the properties of any atomic object can be understood only in terms of the object's interaction with the observer.

Scientists like myself merely use their gifts to show up that which already exists, and we look small compared to the artists who create works of beauty out of themselves. If a good fairy came and offered me back my youth, asking me which gifts I would rather have, those to make visible a thing which exists but which no man has ever seen before, or the genius needed to create, in a style of architecture never imagined before, the great Town Hall in which we are dining tonight, I might be tempted to choose the latter.

The Builder of this Universe was wise,
He plann'd all souls, all systems, planets, particles:
The Plan He shap'd all Worlds and Æons by,
Was—Heavens !—was thy small Nine-and-thirty Articles!

The condensed air becomes attached to [the metallic calx], and adheres little by little to the smallest of its particles: thus its weight increases from the beginning to the end: but when all is saturated, it can take up no more.

The end of the eighteenth and the beginning of the nineteenth century were remarkable for the small amount of scientific movement going on in this country, especially in its more exact departments. ... Mathematics were at the last gasp, and Astronomy nearly so—I mean in those members of its frame which depend upon precise measurement and systematic calculation. The chilling torpor of routine had begun to spread itself over all those branches of Science which wanted the excitement of experimental research.

The theory here developed is that mega-evolution normally occurs among small populations that become preadaptive and evolve continuously (without saltation, but at exceptionally rapid rates) to radically different ecological positions. The typical pattern involved is probably this: A large population is fragmented into numerous small isolated lines of descent. Within these, inadaptive differentiation and random fixation of mutations occur. Among many such inadaptive lines one or a few are preadaptive, i.e., some of their characters tend to fit them for available ecological stations quite different from those occupied by their immediate ancestors. Such groups are subjected to strong selection pressure and evolve rapidly in the further direction of adaptation to the new status. The very few lines that successfully achieve this perfected adaptation then become abundant and expand widely, at the same time becoming differentiated and specialized on lower levels within the broad new ecological zone.

There is no smallest among the small and no largest among the large; but always something still smaller and something still larger.

Those individuals who give moral considerations a much greater weight than considerations of expediency represent a comparatively small minority, five percent of the people perhaps. But, In spite of their numerical inferiority, they play a major role in our society because theirs is the voice of the conscience of society.

Who then understands the reciprocal flux and reflux of the infinitely great and the infinitely small, the echoing of causes in the abysses of being, and the avalanches of creation?

Whoopie! Man, that may have been a small one for Neil but that's a long one for me.
(Commenting as the third man to step on the lunar surface, though of smaller stature, 5' 6", than Neil Armstrong.)

Why are atoms so small? ... Many examples have been devised to bring this fact home to an audience, none of them more impressive than the one used by Lord Kelvin: Suppose that you could mark the molecules in a glass of water, then pour the contents of the glass into the ocean and stir the latter thoroughly so as to distribute the marked molecules uniformly throughout the seven seas; if you then took a glass of water anywhere out of the ocean, you would find in it about a hundred of your marked molecules.

[T]he small is great, the great is small; all is in equilibrium in necessity...