A cosmic mystery of immense proportions, once seemingly on the verge of solution, has deepened and left astronomers and astrophysicists more baffled than ever. The crux ... is that the vast majority of the mass of the universe seems to be missing.
[Reporting a Nature article discrediting explanation of invisible mass being due to neutrinos]

It is obvious that man dwells in a splendid universe, a magnificent expanse of earth and sky and heaven, which manifestly is built on a majestic plan, maintains some mighty design, though man himself cannot grasp it. Yet for him it is not a pleasant or satisfying world. In his few moments of respite from labor or from his enemies, he dreams that this very universe might indeed be perfect, its laws operating just as now they seem to do, and yet he and it somehow be in full accord. The very ease with which he can frame this image to himself makes the reality all the more mocking. ... It is only too clear that man is not at home in this universe, and yet he is not good enough to deserve a better.

Perhaps the problem is the seeming need that people have of making black-and-white cutoffs when it comes to certain mysterious phenomena, such as life and consciousness. People seem to want there to be an absolute threshold between the living and the nonliving, and between the thinking and the “merely mechanical,” ... But the onward march of science seems to force us ever more clearly into accepting intermediate levels of such properties.

The air of caricature never fails to show itself in the products of reason applied relentlessly and without correction. The observation of clinical facts would seem to be a pursuit of the physician as harmless as it is indispensable. [But] it seemed irresistibly rational to certain minds that diseases should be as fully classifiable as are beetles and butterflies. This doctrine ... bore perhaps its richest fruit in the hands of Boissier de Sauvauges. In his Nosologia Methodica published in 1768 ... this Linnaeus of the bedside grouped diseases into ten classes, 295 genera, and 2400 species.

The Greeks made Space the subject-matter of a science of supreme simplicity and certainty. Out of it grew, in the mind of classical antiquity, the idea of pure science. Geometry became one of the most powerful expressions of that sovereignty of the intellect that inspired the thought of those times. At a later epoch, when the intellectual despotism of the Church, which had been maintained through the Middle Ages, had crumbled, and a wave of scepticism threatened to sweep away all that had seemed most fixed, those who believed in Truth clung to Geometry as to a rock, and it was the highest ideal of every scientist to carry on his science 'more geometrico.'