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Who said: “The path towards sustainable energy sources will be long and sometimes difficult. But America cannot resist this transition, we must lead it... That is how we will preserve our planet, commanded to our care by God. That’s what will lend meaning to the creed our fathers once declared.”
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Research Quotes (358 quotes)

'Normal science' means research firmly based upon one or more past scientific achievements, achievements that some particular scientific community acknowledges for a time as supplying the foundation for its further practice.
The Structure of Scientific Revolutions (1962), 10.
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‘Endow scientific research and we shall know the truth, when and where it is possible to ascertain it;’' but the counterblast is at hand: ‘To endow research is merely to encourage the research for endowment; the true man of science will not be held back by poverty, and if science is of use to us, it will pay for itself.’ Such are but a few samples of the conflict of opinion which we find raging around us.
The Grammar of Science (1892), 5.
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'Science in itself' is nothing, for it exists only in the human beings who are its bearers. 'Science for its own sake' usually means nothing more than science for the sake of the people who happen to be pursuing it.
'Standpoints in Scientific Medicine', Disease, Life, and Man: Selected Essays (1958), 42.
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...on opening the incubator I experienced one of those rare moments of intense emotion which reward the research worker for all his pains: at first glance I saw that the broth culture, which the night before had been very turbid was perfectly clear: all the bacteria had vanished... as for my agar spread it was devoid of all growth and what caused my emotion was that in a flash I understood: what causes my spots was in fact an invisible microbe, a filterable virus, but a virus parasitic on bacteria. Another thought came to me also, If this is true, the same thing will have probably occurred in the sick man. In his intestine, as in my test-tube, the dysentery bacilli will have dissolved away under the action of their parasite. He should now be cured.
In Allan Chase, Magic Shots: A Human and Scientific Account of the Long and Continuing Struggle to Eradicated Infectious Diseases by Vaccination (1982), 249-250. Also in Allan J. Tobin and Jennie Dusheck, Asking About Life (2005), 206.
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Als Physiker, der sein ganzes Leben der nüchternen Wissenschaft, der Erforschung der Materie widmete, bin ich sicher von dem Verdacht frei, für einen Schwarmgeist gehalten zu werden. Und so sage ich nach meinen Erforschungen des Atoms dieses: Es gibt keine Materie an sich. Alle Materie entsteht und besteht nur durch eine Kraft, welche die Atomteilchen in Schwingung bringt und sie zum winzigsten Sonnensystem des Alls zusammenhält. Da es im ganzen Weltall aber weder eine intelligente Kraft noch eine ewige Kraft gibt - es ist der Menschheit nicht gelungen, das heißersehnte Perpetuum mobile zu erfinden - so müssen wir hinter dieser Kraft einen bewußten intelligenten Geist annehmen. Dieser Geist ist der Urgrund aller Materie.
As a man who has devoted his whole life to the most clear headed science, to the study of matter, I can tell you as a result of my research about atoms this much: There is no matter as such. All matter originates and exists only by virtue of a force which brings the particle of an atom to vibration and holds this most minute solar system of the atom together. We must assume behind this force the existence of a conscious and intelligent mind. This mind is the matrix of all matter.
Lecture, 'Das Wesen der Materie' [The Essence/Nature/Character of Matter], Florence, Italy (1944). Archiv zur Geschichte der Max-Planck-Gesellschaft, Abt. Va, Rep. 11 Planck, Nr. 1797. Excerpt in Gregg Braden, The Spontaneous Healing of Belief: Shattering the Paradigm of False Limits (2009), 334-35. Note: a number of books showing this quote cite it as from Planck's Nobel Prize acceptance speech (1918), which the Webmaster has checked, and does not see this quote therein.
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Clarke's First Law: When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong.
'Hazards of Prophecy: The Failure of Imagination'. In the collection. Profiles of the Future: An Enquiry into the Limits of the Possible (1962, rev. 1973), 14.
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Clarke's Second Law: The only way of discovering the limits of the possible is to venture a little way past them into the impossible.
Profiles of the Future: An Enquiry into the Limits of the Possible (1962, rev. 1973), 21.
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Ihre Arbeit ist gekrönt worden mit dem Nobel Preis für Otto Hahn.
Her work has been crowned by the Nobel Prize for Otto Hahn.
Anonymous
Said to observe that she did not herself receive recognition of her research.
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Les Leucocytes Et L'esprit De Sacrif1ce. — Il semble, d'après les recherches de De Bruyne (Phagocytose, 1895) et de ceux qui le citent, que les leucocytes des Lamellibranches — probablement lorsqu'ils ont phagocyté, qu'ils se sont chargés de résidus et de déchets, qu'ils ont, en un mot, accompli leur rôle et bien fait leur devoir — sortent du corps de l'animal et vont mourir dans le milieu ambiant. Ils se sacrifient. Après avoir si bien servi l'organisme par leur activité, ils le servent encore par leur mort en faisant place aux cellules nouvelles, plus jeunes.
N'est-ce pas la parfaite image du désintéressement le plus noble, et n'y a-t-il point là un exemple et un modèle? Il faut s'en inspirer: comme eux, nous sommes les unités d'un grand corps social; comme eux, nous pouvons le servir et envisager la mort avec sérénité, en subordonnant notre conscience individuelle à la conscience collective.
(30 Jan 1896)
Leukocytes and The Spirit Of Sacrifice. - It seems, according to research by De Bruyne (Phagocytosis, 1885) and those who quote it, that leukocytes of Lamellibranches [bivalves] - likely when they have phagocytized [ingested bacteria], as they become residues and waste, they have, in short, performed their role well and done their duty - leave the body of the animal and will die in the environment. They sacrifice themselves. Having so well served the body by their activities, they still serve in their death by making room for new younger cells.
Isn't this the perfect image of the noblest selflessness, and thereby presents an example and a model? It should be inspiring: like them, we are the units of a great social body, like them, we can serve and contemplate death with equanimity, subordinating our individual consciousness to collective consciousness.
In Recueil d'Œuvres de Léo Errera: Botanique Générale (1908), 194. Google translation by Webmaster. Please give feedback if you can improve it.
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Nisi credideritis, non intelligitis.
Unless you believe, you will not understand.
De Ubero Arbitrio (On Free Choice of the Will) [386], Book I, chapter 2, section 4 (Augustine quoting from Isaiah 7:9).
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On examinations: Das Wissen ist der Tad der Forschung.
Knowledge is the death of research.
Nernst's motto.
Erwin N. Hiebert, 'Hermann Walther Nemst', in C. C. Gillispie (ed.), The Dictionary of Scientific Biography (1981), Supplement, Vol. 15, 450.
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[Recalling Professor Ira Remsen's remarks (1895) to a group of his graduate students about to go out with their degrees into the world beyond the university:]
He talked to us for an hour on what was ahead of us; cautioned us against giving up the desire to push ahead by continued study and work. He warned us against allowing our present accomplishments to be the high spot in our lives. He urged us not to wait for a brilliant idea before beginning independent research, and emphasized the fact the Lavoisier's first contribution to chemistry was the analysis of a sample of gypsum. He told us that the fields in which the great masters had worked were still fruitful; the ground had only been scratched and the gleaner could be sure of ample reward.
Quoted in Frederick Hutton Getman, The Life of Ira Remsen (1980), 73.
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[When recording electrical impulses from a frog nerve-muscle preparation seemed to show a tiresomely oscillating electrical artefact—but only when the muscle was hanging unsupported.] The explanation suddenly dawned on me ... a muscle hanging under its own weight ought, if you come to think of it, to be sending sensory impulses up the nerves coming from the muscle spindles ... That particular day’s work, I think, had all the elements that one could wish for. The new apparatus seemed to be misbehaving very badly indeed, and I suddenly found it was behaving so well that it was opening up an entire new range of data ... it didn’t involve any particular hard work, or any particular intelligence on my part. It was just one of those things which sometimes happens in a laboratory if you stick apparatus together and see what results you get.
From 'Memorable experiences in research', Diabetes (1954), 3, 17-18. As cited in Alan McComa, Galvani's Spark: The Story of the Nerve Impulse (2011), 102-103.
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A biologist, if he wishes to know how many toes a cat has, does not "frame the hypothesis that the number of feline digital extremities is 4, or 5, or 6," he simply looks at a cat and counts. A social scientist prefers the more long-winded expression every time, because it gives an entirely spurious impression of scientificness to what he is doing.
In Science is a Sacred Cow (1950), 151.
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A drop from the nose of Fleming, who had a cold, fell onto an agar plate where large yellow colonies of a contaminant had grown, and lysosyme was discovered. He made this important discovery because when he saw that the colonies of the contaminant were fading, his mind went straight to the right cause of the phenomenon he was observing—that the drop from his nose contained a lytic substance. And also immediately, he thought that this substance might be present in many secretions and tissues of the body. And he found this was so—the substance was in tears, saliva, leucocytes, skin, fingernails, mother's milk—thus very widely distributed in amounts and also in plants.
Personal recollections of Alexander Fleming by Lady Amelia Fleming. Quoted in Molecular Cloning (2001), Vol. 1, 153.
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A good deal of my research in physics has consisted in not setting out to solve some particular problem, but simply examining mathematical equations of a kind that physicists use and trying to fit them together in an interesting way, regardless of any application that the work may have. It is simply a search for pretty mathematics. It may turn out later to have an application. Then one has good luck. At age 78.
International Journal of Theoretical Physics (1982), 21, 603. In A. Pais, 'Playing With Equations, the Dirac Way'. Behram N. Kursunoglu (Ed.) and Eugene Paul Wigner (Ed.), Paul Adrien Maurice Dirac: Reminiscences about a Great Physicist (1990), 110.
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A life that stood out as a gospel of self-forgetting service.
He could have added fortune to fame but caring for neither he found happiness and honor in being helpful to the world.
The centre of his world was the south where he was born in slavery some 79 years ago and where he did his work as a creative scientist.
Epitaph on tombstone at Tuskegee University Campus Cemetery, Alabama.
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A number of years ago, when I was a freshly-appointed instructor, I met, for the first time, a certain eminent historian of science. At the time I could only regard him with tolerant condescension.
I was sorry of the man who, it seemed to me, was forced to hover about the edges of science. He was compelled to shiver endlessly in the outskirts, getting only feeble warmth from the distant sun of science- in-progress; while I, just beginning my research, was bathed in the heady liquid heat up at the very center of the glow.
In a lifetime of being wrong at many a point, I was never more wrong. It was I, not he, who was wandering in the periphery. It was he, not I, who lived in the blaze.
I had fallen victim to the fallacy of the “growing edge;” the belief that only the very frontier of scientific advance counted; that everything that had been left behind by that advance was faded and dead.
But is that true? Because a tree in spring buds and comes greenly into leaf, are those leaves therefore the tree? If the newborn twigs and their leaves were all that existed, they would form a vague halo of green suspended in mid-air, but surely that is not the tree. The leaves, by themselves, are no more than trivial fluttering decoration. It is the trunk and limbs that give the tree its grandeur and the leaves themselves their meaning.
There is not a discovery in science, however revolutionary, however sparkling with insight, that does not arise out of what went before. “If I have seen further than other men,” said Isaac Newton, “it is because I have stood on the shoulders of giants.”
Adding A Dimension: Seventeen Essays on the History of Science (1964), Introduction.
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A persistent and age-old instinct makes us want to wander
Into regions yet untrod
And read what is still unread
In the manuscripts of God.
Address upon receiving the Perkin Medal Award, 'The Big Things in Chemistry', The Journal of Industrial and Engineering Chemistry (Feb 1921), 13, No. 2, 163. These lines concluded his remarks, without citation, and since Webmaster has found no other source has assumed the words are his own. Contact Webmaster if you know a different primary source.
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A research problem is not solved by apparatus; it is solved in a man's head.
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Above all, I regret that scientific experiments—some of them mine—should have produced such a terrible weapon as the hydrogen bomb. Regret, with all my soul, but not guilt.
Quoted in 'Moon-Struck Scientist,' New York Times (27 Apr 1961), 42.
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After the discovery of spectral analysis no one trained in physics could doubt the problem of the atom would be solved when physicists had learned to understand the language of spectra. So manifold was the enormous amount of material that has been accumulated in sixty years of spectroscopic research that it seemed at first beyond the possibility of disentanglement. An almost greater enlightenment has resulted from the seven years of Röntgen spectroscopy, inasmuch as it has attacked the problem of the atom at its very root, and illuminates the interior. What we are nowadays hearing of the language of spectra is a true 'music of the spheres' in order and harmony that becomes ever more perfect in spite of the manifold variety. The theory of spectral lines will bear the name of Bohr for all time. But yet another name will be permanently associated with it, that of Planck. All integral laws of spectral lines and of atomic theory spring originally from the quantum theory. It is the mysterious organon on which Nature plays her music of the spectra, and according to the rhythm of which she regulates the structure of the atoms and nuclei.
Atombau und Spektrallinien (1919), viii, Atomic Structure and Spectral Lines, trans. Henry L. Brose (1923), viii.
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All human affairs follow nature's great analogue, the growth of vegetation. There are three periods of growth in every plant. The first, and slowest, is the invisible growth by the root; the second and much accelerated is the visible growth by the stem; but when root and stem have gathered their forces, there comes the third period, in which the plant quickly flashes into blossom and rushes into fruit.
The beginnings of moral enterprises in this world are never to be measured by any apparent growth. ... At length comes the sudden ripeness and the full success, and he who is called in at the final moment deems this success his own. He is but the reaper and not the labourer. Other men sowed and tilled and he but enters into their labours.
Life Thoughts (1858), 20.
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Always preoccupied with his profound researches, the great Newton showed in the ordinary-affairs of life an absence of mind which has become proverbial. It is related that one day, wishing to find the number of seconds necessary for the boiling of an egg, he perceived, after waiting a minute, that he held the egg in his hand, and had placed his seconds watch (an instrument of great value on account of its mathematical precision) to boil!
This absence of mind reminds one of the mathematician Ampere, who one day, as he was going to his course of lectures, noticed a little pebble on the road; he picked it up, and examined with admiration the mottled veins. All at once the lecture which he ought to be attending to returned to his mind; he drew out his watch; perceiving that the hour approached, he hastily doubled his pace, carefully placed the pebble in his pocket, and threw his watch over the parapet of the Pont des Arts.
Popular Astronomy: a General Description of the Heavens (1884), translated by J. Ellard Gore, (1907), 93.
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American scientific companies are cross-breeding humans and animals and coming up with mice with fully functioning human brains.
From transcript of interview on TV show, The O'Reilly Factor (15 Nov 2007).
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Among those whom I could never pursuade to rank themselves with idlers, and who speak with indignation of my morning sleeps and nocturnal rambles, one passes the day in catching spiders, that he may count their eyes with a microscope; another exhibits the dust of a marigold separated from the flower with a dexterity worthy of Leuwenhoweck himself. Some turn the wheel of electricity; some suspend rings to a lodestone, and find that what they did yesterday, they can do again to-day.—Some register the changes of the wind, and die fully convinced that the wind is changeable.—There are men yet more profound, who have heard that two colorless liquors may produce a color by union, and that two cold bodies will grow hot of they are mingled: they mingle them, and produce the effect expected, say it is strange, and mingle them again.
In Tryon Edwards, A Dictionary of Thoughts (1908), 243.
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An intelligent patient, private or otherwise, to whom you have taken the trouble to explain the nature of the investigation, makes the best laboratory animal.
'Some of the 'Do's' and 'Do-Nots' in Clinical Investigation,' Journal of Clinical Investigation (1944), 23, 921-26.
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And so, after many years, victory has come, and the romance of exploration, of high hopes and bitter disappointment, will in a few years simply be recorded in the text-books of organic chemistry in a few terse sentences.
Recent Developments in the Vitamin A Field', The Pedlar Lecture, 4 Dec 1947, Journal of the Chemical Society, Part I (1948), 393.
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And when with excellent Microscopes I discern in otherwise invisible Objects the Inimitable Subtlety of Nature's Curious Workmanship; And when, in a word, by the help of Anatomicall Knives, and the light of Chymicall Furnaces, I study the Book of Nature, and consult the Glosses of Aristotle, Epicurus, Paracelsus, Harvey, Helmont, and other learn'd Expositors of that instructive Volumne; I find my self oftentimes reduc'd to exclaim with the Psalmist, How manifold are thy works, O Lord? In wisdom hast thou made them all.
Some Motives and Incentives to the Love of God (1659), 56-7.
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Animals, even plants, lie to each other all the time, and we could restrict the research to them, putting off the real truth about ourselves for the several centuries we need to catch our breath. What is it that enables certain flowers to resemble nubile insects, or opossums to play dead, or female fireflies to change the code of their flashes in order to attract, and then eat, males of a different species?
In Late Night Thoughts on Listening to Mahler's Ninth Symphony(1984), 131.
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Anybody who has been seriously engaged in scientific work of any kind realizes that over the entrance to the gates of the temple of science are written the words: Ye must have faith. It is a quality which the scientist cannot dispense with.
Where is Science Going?, translated by James Vincent Murphy (1932), 214.
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As our researches have made clear, an animal high in the organic scale only reaches this rank by passing through all the intermediate states which separate it from the animals placed below it. Man only becomes man after traversing transitional organisatory states which assimilate him first to fish, then to reptiles, then to birds and mammals.
Annales des Sciences Naturelles (1834), 2 (ii), 248. Trans. in E. S. Russell, Form and Function (1916), 82.
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As was predicted at the beginning of the Human Genome Project, getting the sequence will be the easy part as only technical issues are involved. The hard part will be finding out what it means, because this poses intellectual problems of how to understand the participation of the genes in the functions of living cells.
Loose Ends from Current Biology (1997), 71.
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At the entrance to the observatory Stj?rneborg located underground, Tycho Brahe built a Ionic portal. On top of this were three sculptured lions. On both sides were inscriptions and on the backside was a longer inscription in gold letters on a porfyr stone: Consecrated to the all-good, great God and Posterity. Tycho Brahe, Son of Otto, who realized that Astronomy, the oldest and most distinguished of all sciences, had indeed been studied for a long time and to a great extent, but still had not obtained sufficient firmness or had been purified of errors, in order to reform it and raise it to perfection, invented and with incredible labour, industry, and expenditure constructed various exact instruments suitable for all kinds of observations of the celestial bodies, and placed them partly in the neighbouring castle of Uraniborg, which was built for the same purpose, partly in these subterranean rooms for a more constant and useful application, and recommending, hallowing, and consecrating this very rare and costly treasure to you, you glorious Posterity, who will live for ever and ever, he, who has both begun and finished everything on this island, after erecting this monument, beseeches and adjures you that in honour of the eternal God, creator of the wonderful clockwork of the heavens, and for the propagation of the divine science and for the celebrity of the fatherland, you will constantly preserve it and not let it decay with old age or any other injury or be removed to any other place or in any way be molested, if for no other reason, at any rate out of reverence to the creator's eye, which watches over the universe. Greetings to you who read this and act accordingly. Farewell!
(Translated from the original in Latin)
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Attempt the end and never stand to doubt;
Nothing's so hard, but search will find it out.
'Seeke and Finde', Hesperides: Or, the Works Both Humane and Divine of Robert Herrick Esq. (1648). In J. Max Patrick (ed.), The Complete Poetry of Robert Herrick (1963), 411.

AZT stood up and said, 'Stop your pessimism. Stop your sense of futility. Go back to the lab. Go back to development. Go back to clinical trials. Things will work.'
[On the impact of AZT emerging as the long-sought first significant AIDS drug.]
As quoted in Emily Langer, 'Researcher Jerome P. Horwitz, 93, created AZT, the first approved treatment for HIV/AIDS' Washington Post (19 Sep 2012). The article was excerpted on blogs, sometimes referring to this quote by saying "AZT was more a cure for fatalism than for AIDS."
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Bankers regard research as most dangerous a thing that makes banking hazardous due to the rapid changes it brings about in industry.
Address (1927), quoted in U.S. National Resources Committee Technology and Planning, Washington 1937, 5-6. Also U.S. Government Report, Technological Trends (1937), 63.
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Basic research at universities comes in two varieties: research that requires big bucks and research that requires small bucks. Big bucks research is much like government research and in fact usually is government research but done for the government under contract. Like other government research, big bucks academic research is done to understand the nature and structure of the universe or to understand life, which really means that it is either for blowing up the world or extending life, whichever comes first. Again, that's the government's motivation. The universities' motivation for conducting big bucks research is to bring money in to support professors and graduate students and to wax the floors of ivy-covered buildings. While we think they are busy teaching and learning, these folks are mainly doing big bucks basic research for a living, all the while priding themselves on their terrific summer vacations and lack of a dress code.
Smalls bucks research is the sort of thing that requires paper and pencil, and maybe a blackboard, and is aimed primarily at increasing knowledge in areas of study that don't usually attract big bucks - that is, areas that don't extend life or end it, or both. History, political science, and romance languages are typically small bucks areas of basic research. The real purpose of small bucks research to the universities is to provide a means of deciding, by the quality of their small bucks research, which professors in these areas should get tenure.
Accidental Empires (1992), 78.
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Basic research is like shooting an arrow into the air and, where it lands, painting a target.
Quoted In A. Mackay (ed.), A Dictionary of Scientific Quotations (1991), 2.

Basic research is what I am doing when I don't know what I am doing.
Attributed.

Basic scientific research is scientific capital.
In 'Science - The Endless Frontier: A Report to the President' (Jul 1945), collected in John Dewey (ed.) and Julius A. Sigler (ed.), Science, Technology, and Society (1997), 13. Bush was the first director of the Office of Scientific Research and Development during World War II.
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Beware of finding what you're looking for.
A favorite aphorism he often used.
Though widely seen attributed as a caution Hamming often used, webmaster has found no evidence that he originated the saying. If you know a primary source, please contact webmaster.
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Bohr's standpoint, that a space-time description is impossible, I reject a limine. Physics does not consist only of atomic research, science does not consist only of physics, and life does not consist only of science. The aim of atomic research is to fit our empirical knowledge concerning it into our other thinking. All of this other thinking, so far as it concerns the outer world, is active in space and time. If it cannot be fitted into space and time, then it fails in its whole aim and one does not know what purpose it really serves.
Letter to Willy Wien (25 Aug 1926). Quoted in Walter Moore, Schrödinger: Life and Thought (1989), 226.
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But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.
Ancient Medicine, in Hippocrates, trans. W. H. S. Jones (1923), Vol. I, 15.
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But the World being once fram'd, and the course of Nature establish'd, the Naturalist, (except in some few cases, where God, or Incorporeal Agents interpose), has recourse to the first Cause but for its general and ordinary Support and Influence, whereby it preserves Matter and Motion from Annihilation or Desition; and in explicating particular phenomena, considers onely the Size, Shape, Motion, (or want of it) Texture, and the resulting Qualities and Attributes of the small particles of Matter.
The Origine of Formes and Qualities (1666), 194.
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But when you come right down to it, the reason that we did this job is because it was an organic necessity. If you are a scientist you cannot stop such a thing. If you are a scientist you believe that it is good to find out how the world works; that it is good to find out what the realities are; that it is good to turn over to mankind at large the greatest possible power to control the world and to deal with it according to its lights and values.
Regarding the atomic bomb project.
From speech at Los Alamos (17 Oct 1945). Quoted in David C. Cassidy, J. Robert Oppenheimer and the American Century (2009), 214.
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But, because my private lectures and domestic pupils are a great hinderance and intteruption of my studies, I wish to live entirely exempt from the former, and in great measure from the latter. … in short, I should wish to gain my bread from my writings.
Reply upon being offered a professorship.
Quoted in John Elliot Drinkwater Bethune, Life of Galileo Galilei (1832), 63.
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Cancer is a biological, not a statistical problem.
Anonymous
'Shoot Out in Marlboro Country', Mother Jones Magazine (Jan 1979), 36.
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Chemical research conducts to the knowledge of philosophical truth, and forms the mind to philosophical enlargement and accuracy of thought, more happily than almost any other species of investigation in which the human intellect can be employed.
Quote following title page of Samuel Parkes, A Chemical Catechism With Notes, Illustrations and Experiments (8th ed. 1818).
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Chemistry is one of those branches of human knowledge which has built itself upon methods and instruments by which truth can presumably be determined. It has survived and grown because all its precepts and principles can be re-tested at any time and anywhere. So long as it remained the mysterious alchemy by which a few devotees, by devious and dubious means, presumed to change baser metals into gold, it did not flourish, but when it dealt with the fact that 56 g. of fine iron, when heated with 32 g. of flowers of sulfur, generated extra heat and gave exactly 88 g. of an entirely new substance, then additional steps could be taken by anyone. Scientific research in chemistry, since the birth of the balance and the thermometer, has been a steady growth of test and observation. It has disclosed a finite number of elementary reagents composing an infinite universe, and it is devoted to their inter-reaction for the benefit of mankind.
Address upon receiving the Perkin Medal Award, 'The Big Things in Chemistry', The Journal of Industrial and Engineering Chemistry (Feb 1921), 13, No. 2, 163.
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Copying extensively from one source is plagiarism; copying extensively from several is research.
Anonymous
N. E. Renton, Compendium of Good Writing: A Plain English Guide (2007), 113.
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Creative imagination is likely to find corroborating novel evidence even for the most 'absurd' programme, if the search has sufficient drive. This look-out for new confirming evidence is perfectly permissible. Scientists dream up phantasies and then pursue a highly selective hunt for new facts which fit these phantasies. This process may be described as 'science creating its own universe' (as long as one remembers that 'creating' here is used in a provocative-idiosyncratic sense). A brilliant school of scholars (backed by a rich society to finance a few well-planned tests) might succeed in pushing any fantastic programme ahead, or alternatively, if so inclined, in overthrowing any arbitrarily chosen pillar of 'established knowledge'.
'Falsification and the Methodology of Scientific Research Programmes', in I. Lakatos and A. Musgrave (eds.), Criticism and the Growth of Knowledge: Proceedings of the International Colloquium in the Philosophy of Science, London 1965 (1970), Vol. 4, 187-8.
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Dick Drew took a bunch of misfits—people who wouldn’t fly in formation—and he put together a lab that created technologies that account for 20 percent of 3M's sales in 2000.
Art Fry
As quoted in W. James McNerney Jr., A Century of Innovation: The 3M Story (2002), 26.
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Direct observation of the testimony of the earth ... is a matter of the laboratory, of the field naturalist, of indefatigable digging among the ancient archives of the earth's history. If Mr. Bryan, with an open heart and mind, would drop all his books and all the disputations among the doctors and study first hand the simple archives of Nature, all his doubts would disappear; he would not lose his religion; he would become an evolutionist.
'Evolution and Religion', New York Times (5 Mar 1922), 91. Written in response to an article a few days earlier in which William Jennings Bryan challenged the theory of evolution as lacking proof.
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Do experimental work but keep in mind that other investigators in the same field will consider your discoveries as less than one fourth as important as they seem to you.
In Victor Shelford, The Ecology of North America (1963), v.
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Do not do anything that anyone else can do readily.
In Alan R. Earls and Nasrin Rohani, Polaroid (2005), 16.
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Do what you can where you are with what you have.
The Homiletic Review, Vol. 83-84 (1922), Vol. 84, 380.

Doctors have been exposed—you always will be exposed—to the attacks of those persons who consider their own undisciplined emotions more important than the world's most bitter agonies—the people who would limit and cripple and hamper research because they fear research may be accompanied by a little pain and suffering.
Doctors (1908), 28-9.
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Each generation has its few great mathematicians, and mathematics would not even notice the absence of the others. They are useful as teachers, and their research harms no one, but it is of no importance at all. A mathematician is great or he is nothing.
Reflections: Mathematics and Creativity', New Yorker (1972), 47, No. 53, 39-45. In Douglas M. Campbell, John C. Higgins (eds.), Mathematics: People, Problems, Results (1984), Vol. 2, 3.
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Elaborate apparatus plays an important part in the science of to-day, but I sometimes wonder if we are not inclined to forget that the most important instrument in research must always be the mind of man.
The Art of Scientific Investigation (1951), ix.
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Embryonic stem cell research is at the leading edge of a series of moral hazards.
'Address to the Nation on Stem Cell Research', (9 Aug 2001) in Public Papers Of The Presidents Of The United States, George W. Bush, 2001 (2004), Book 2, 955.
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Every discovery opens a new field for investigation of facts, shows us the imperfection of our theories. It has justly been said, that the greater the circle of light, the greater the boundary of darkness by which it is surrounded.
Humphry Davy and John Davy, 'Consolations in Travel--Dialogue V--The Chemical Philosopher', The Collected Works of Sir Humphry Davy (1840), Vol. 9, 362.
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Every scientist, through personal study and research, completes himself and his own humanity. ... Scientific research constitutes for you, as it does for many, the way for the personal encounter with truth, and perhaps the privileged place for the encounter itself with God, the Creator of heaven and earth. Science shines forth in all its value as a good capable of motivating our existence, as a great experience of freedom for truth, as a fundamental work of service. Through research each scientist grows as a human being and helps others to do likewise.
Address to the members of the Pontifical Academy of Sciences (13 Nov 2000). In L'Osservatore Romano (29 Nov 2000), translated in English edition, 5.
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Experimenters are the shock troops of science.
'The Meaning and Limits of Exact Science', Science (30 Sep 1949), 110, No. 2857, 325. Advance reprinting of chapter from book Max Planck, Scientific Autobiography (1949), 110.
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Facts, and facts alone, are the foundation of science... When one devotes oneself to experimental research it is in order to augment the sum of known facts, or to discover their mutual relations.
Precis elementaire de Physiologie (1816), ii. Trans. J. M. D. Olmsted, François Magendie: Pioneer in Experimental Physiology and Scientific Medicine in XIX Century France (1944), 62.
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Firm support has been found for the assertion that electricity occurs at thousands of points where we at most conjectured that it was present. Innumerable electrical particles oscillate in every flame and light source. We can in fact assume that every heat source is filled with electrons which will continue to oscillate ceaselessly and indefinitely. All these electrons leave their impression on the emitted rays. We can hope that experimental study of the radiation phenomena, which are exposed to various influences, but in particular to the effect of magnetism, will provide us with useful data concerning a new field, that of atomistic astronomy, as Lodge called it, populated with atoms and electrons instead of planets and worlds.
'Light Radiation in a Magnetic Field', Nobel Lecture, 2 May 1903. In Nobel Lectures: Physics 1901-1921 (1967), 40.
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For God's sake, stop researching for a while and begin to think.
The Crisis in the University (1949), 183.
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Formula for breakthroughs in research: Take young researchers, put them together in virtual seclusion, give them an unprecedented degree of freedom and turn up the pressure by fostering competitiveness.
In James Beasley Simpson, Simpson's Contemporary Quotations (1988), 145.
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Frequently, I have been asked if an experiment I have planned is pure or applied science; to me it is more important to know if the experiment will yield new and probably enduring knowledge about nature. If it is likely to yield such knowledge, it is, in my opinion, good fundamental research; and this is more important than whether the motivation is purely aesthetic satisfaction on the part of the experimenter on the one hand or the improvement of the stability of a high-power transistor on the other.
Quoted in Richard R. Nelson, 'The Link Between Science and Invention: The Case of the Transistor,' The Rate and Direction of the Inventive Activity (1962). In Daniel S. Greenberg, The Politics of Pure Science (1999), 32, footnote.
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From the point of view of the pure morphologist the recapitulation theory is an instrument of research enabling him to reconstruct probable lines of descent; from the standpoint of the student of development and heredity the fact of recapitulation is a difficult problem whose solution would perhaps give the key to a true understanding of the real nature of heredity.
Form and Function: A Contribution to the History of Animal Morphology (1916), 312-3.
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Genetics as a whole is the great over-hyped science, and geneticists know that even if they don't say it. All that genetics really is is anatomy plus an enormous research group grant. It's what anatomists did in the fifteenth century-looking at the heart and seeing how it worked. Now, we are doing the same with DNA
Quoted by Sean O'Hagan, in 'End of sperm report', The Observer (14 Sep 2002).
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He who sees things grow from the beginning will have the best view of them.
Aristotle
Quoted in J. Lima-de-Faria (ed.), Historical Atlas of Crystallography (1990), vi.
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Hieron asked Archimedes to discover, without damaging it, whether a certain crown or wreath was made of pure gold, or if the goldsmith had fraudulently alloyed it with some baser metal. While Archimedes was turning the problem over in his mind, he chanced to be in the bath house. There, as he was sitting in the bath, he noticed that the amount of water that was flowing over the top of it was equal in volume to that part of his body that was immersed. He saw at once a way of solving the problem. He did not delay, but in his joy leaped out of the bath. Rushing naked through the streets towards his home, he cried out in a loud voice that he had found what he sought. For, as he ran, he repeatedly shouted in Greek; “Eureka! Eurekal I’ve found it! I’ve found it!”
Vitrivius Pollio, De Architectura, ix, prologue, section 10.
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Hitherto the principle of causality was universally accepted as an indispensable postulate of scientific research, but now we are told by some physicists that it must be thrown overboard. The fact that such an extraordinary opinion should be expressed in responsible scientific quarters is widely taken to be significant of the all-round unreliability of human knowledge. This indeed is a very serious situation.
In Where is Science Going? (1932), 66.
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Hofstadter's Law: It always takes longer than you expect, even when you take into account Hofstadter's Law.
Gödel, Escher, Bach: An Eternal Golden Braid (1979), 152.
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Hopes are always accompanied by fears, and, in scientific research, the fears are liable to become dominant.
At age 67.
Eureka (Oct 1969), No.32, 2-4.
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How did Biot arrive at the partial differential equation? [the heat conduction equation] . . . Perhaps Laplace gave Biot the equation and left him to sink or swim for a few years in trying to derive it. That would have been merely an instance of the way great mathematicians since the very beginnings of mathematical research have effortlessly maintained their superiority over ordinary mortals.
The Tragicomical History of Thermodynamics, 1822-1854 (1980), 51.
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How did I discover saccharin? Well, it was partly by accident and partly by study. I had worked a long time on the compound radicals and substitution products of coal tar... One evening I was so interested in my laboratory that I forgot about my supper till quite late, and then rushed off for a meal without stopping to wash my hands. I sat down, broke a piece of bread, and put it to my lips. It tasted unspeakably sweet. I did not ask why it was so, probably because I thought it was some cake or sweetmeat. I rinsed my mouth with water, and dried my moustache with my napkin, when, to my surprise the napkin tasted sweeter than the bread. Then I was puzzled. I again raised my goblet, and, as fortune would have it, applied my mouth where my fingers had touched it before. The water seemed syrup. It flashed on me that I was the cause of the singular universal sweetness, and I accordingly tasted the end of my thumb, and found it surpassed any confectionery I had ever eaten. I saw the whole thing at once. I had discovered some coal tar substance which out-sugared sugar. I dropped my dinner, and ran back to the laboratory. There, in my excitement, I tasted the contents of every beaker and evaporating dish on the table.
Interview with American Analyst. Reprinted in Pacific Record of Medicine and Surgery (1886), 1, No. 3, 78.
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How many times did the sun shine, how many times did the wind howl over the desolate tundras, over the bleak immensity of the Siberian taigas, over the brown deserts where the Earth’s salt shines, over the high peaks capped with silver, over the shivering jungles, over the undulating forests of the tropics! Day after day, through infinite time, the scenery has changed in imperceptible features. Let us smile at the illusion of eternity that appears in these things, and while so many temporary aspects fade away, let us listen to the ancient hymn, the spectacular song of the seas, that has saluted so many chains rising to the light.
Tectonics of Asia (1924), 165, trans. Albert V. and Marguerite Carozzi.
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How many times did the sun shine, how many times did the wind howl over the desolate tundras, over the bleak immensity of the Siberian taigas, over the brown deserts where the Earth’s salt shines, over the high peaks capped with silver, over the shivering jungles, over the undulating forests of the tropics! Day after day, through infinite time, the scenery has changed in imperceptible features. Let us smile at the illusion of eternity that appears in these things, and while so many temporary aspects fade away, let us listen to the ancient hymn, the spectacular song of the seas, that has saluted so many chains rising to the light.
Tectonics of Asia (1924), 165, trans. Albert V. and Marguerite Carozzi.
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I always feel like our descendants—they're going to be upset with us for wrecking the planet anyway—but they're really going to be mad that we didn't even bother to take a good picture. [On the importance of thorough research of even a little ant species.]
Quoted from NPR radio interview, also published on NPR web page by Christopher Joyce, Morning Edition (1 Aug 2013).
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I am aware that those hateful persons called Original Researchers now maintain that Raleigh was not the man; but to them I turn a deaf ear.
On who offered his coat for Queen Elizabeth I.
My Lady Nicotine (1890), 107.

I am busy just now again on Electro-Magnetism and think I have got hold of a good thing but can't say; it may be a weed instead of a fish that after all my labour I may at last pull up.
Letter to Richard Phillips, 23 Sep 1831. In Michael Faraday, Bence Jones (ed.), The Life and Letters of Faraday (1870), Vol. 2, 3.
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I am now convinced that we have recently become possessed of experimental evidence of the discrete or grained nature of matter, which the atomic hypothesis sought in vain for hundreds and thousands of years. The isolation and counting of gaseous ions, on the one hand, which have crowned with success the long and brilliant researches of J.J. Thomson, and, on the other, agreement of the Brownian movement with the requirements of the kinetic hypothesis, established by many investigators and most conclusively by J. Perrin, justify the most cautious scientist in now speaking of the experimental proof of the atomic nature of matter, The atomic hypothesis is thus raised to the position of a scientifically well-founded theory, and can claim a place in a text-book intended for use as an introduction to the present state of our knowledge of General Chemistry.
In Grundriss der allgemeinen Chemie (4th ed., 1909), Preface, as cited by Erwin N. Hiebert and Hans-Gunther Korber in article on Ostwald in Charles Coulston Gillespie (ed.), Dictionary of Scientific Biography Supplement 1, Vol 15-16, 464.
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I am sorry that the distinguished leader of the Republican Party in the House states that he is not versed in botany and publicly admits that he does not know anything of these terms or what it is all about; but, Mr. Chairman, it is indeed a sad day for the people of this country when we must close the doors of the laboratories doing research work for the people of the United States.
Speaking (28 Dec 1932) as a member of the 72nd Congress, early in the Great Depression, in opposition to an attempt to eliminate a small amount from the agricultural appropriation bill. As quoted in 'Mayor-Elect La Guardia on Research', Science (1933), New Series, 78, No. 2031, 511.
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I believe in intuition and inspiration. Imagination is more important than knowledge. For knowledge is limited, whereas imagination embraces the entire world, stimulating progress, giving birth to evolution. It is, strictly speaking, a real factor in scientific research.
Cosmic Religion: With Other Opinions and Aphorisms (1931), 97.
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I believe quite simply that the small company of the future will be as much a research organization as it is a manufacturing company.
Written in 1944. Quoted in New York Times (2 Mar 1991), 29.
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I built the solenoid and with great expectations late one evening I pressed the switch which sent a current of 40 amperes through the coil. The result was spectacular—a deafening explosion, the apparatus disappeared, all windows were blown in or out, a wall caved in, and thus ended my pioneering experiment on liquid hydrogen cooled coils! [Recalling the result of his experiment, on 31 Mar 1930, to maximize the magnetic field by cooling the coils of an electromagnet in liquid hydrogen to reduce their resistance.]
'Magnets I have Known', Lecture Notes in Physics (1983), 177, 542-548. Quoted from his memoirs in M.J.M. Leask, 'Obituary: Professor Nicholas Kurti', The Independent (27 Nov 1998).
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I consider then, that generally speaking, to render a reason of an effect or Phaenomenon, is to deduce It from something else in Nature more known than it self, and that consequently there may be divers kinds of Degrees of Explication of the same thing. For although such Explications be the most satisfactory to the Understanding, wherein 'tis shewn how the effect is produc'd by the more primitive and Catholick Affection of Matter, namely bulk, shape and motion, yet are not these Explications to be despis'd, wherein particular effects are deduc'd from the more obvious and familiar Qualities or States of Bodies, ... For in the search after Natural Causes, every new measure of Discovery does both instinct and gratifie the Understanding.
Physiological Essays (1669), 20.
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I could never have known so well how paltry men are, and how little they care for really high aims, if I had not tested them by my scientific researches. Thus I saw that most men only care for science so far as they get a living by it, and that they worship even error when it affords them a subsistence.
Wed 12 Oct 1825. Johann Peter Eckermann, Conversations with Goethe, ed. J. K. Moorhead and trans. J. Oxenford (1971), 119-20.
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I doubt that Fleming could have obtained a grant for the discovery of penicillin on that basis [a requirement for highly detailed research plans] because he could not have said, 'I propose to have an accident in a culture so that it will be spoiled by a mould falling on it, and I propose to recognize the possibility of extracting an antibiotic from this mould.'
Remarks to the Canadian Senate on Science Policy, in From Dream to Discovery: On Being a Scientist (1964). In Ken G. Smith (ed.) and Michael A. Hitt (ed), Great Minds in Management: the Theory of Process Development (2005), 368
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I feel very strongly indeed that a Cambridge education for our scientists should include some contact with the humanistic side. The gift of expression is important to them as scientists; the best research is wasted when it is extremely difficult to discover what it is all about ... It is even more important when scientists are called upon to play their part in the world of affairs, as is happening to an increasing extent.
From essay in Thomas Rice Henn, The Apple and the Spectroscope: Being Lectures on Poetry Designed (in the Main) for Science Students (1951), 142.
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I happen to be a kind of monkey. I have a monkeylike curiosity that makes me want to feel, smell, and taste things which arouse my curiosity, then to take them apart. It was born in me. Not everybody is like that, but a scientific researchist should be. Any fool can show me an experiment is useless. I want a man who will try it and get something out of it.
Quoted in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 357.
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I have always attached great importance to the manner in which an experiment is set up and conducted ... the experiment should be set up to open as many windows as possible on the unforeseen.
(1954). In Charles Coulston Gillespie (ed.), Dictionary of Scientific Biography (1973), Vol. 7, 153.
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I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this—never neglect an extraordinary appearance or happening. It may be—usually is, in fact—a false alarm that leads to nothing, but may on the other hand be the clue provided by fate to lead you to some important advance.
Lecture at Harvard University. Quoted in Joseph Sambrook, David W. Russell, Molecular Cloning (2001), Vol. 1, 153.
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I have little patience with scientists who take a board of wood, look for its thinnest part and drill a great number of holes where drilling is easy.
P. Frank in 'Einstein's Philosophy of Science', Reviews of Modern Physics (1949).
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I have never had any student or pupil under me to aid me with assistance; but have always prepared and made my experiments with my own hands, working & thinking at the same time. I do not think I could work in company, or think aloud, or explain my thoughts at the time. Sometimes I and my assistant have been in the Laboratory for hours & days together, he preparing some lecture apparatus or cleaning up, & scarcely a word has passed between us; — all this being a consequence of the solitary & isolated system of investigation; in contradistinction to that pursued by a Professor with his aids & pupils as in your Universities.
Letter to C. Ransteed, 16 Dec 1857. In L. Pearce Williams (ed.), The Selected Correspondence of Michael Faraday (1971), Vol. 2, 888.
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I have to keep going, as there are always people on my track. I have to publish my present work as rapidly as possible in order to keep in the race. The best sprinters in this road of investigation are Becquerel and the Curies...
Letter to his mother (5 Jan1902). Quoted in A. S. Eve, Rutherford: Being the Life and Letters of the Rt. Hon. Lord Rutherford (1939), 80. In Laurie M. Brown, Abraham Pais and A. B. Pippard, Twentieth Century Physics (1995), 58.
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I have tried to show why I believe that the biologist is the most romantic figure on earth at the present day. At first sight he seems to be just a poor little scrubby underpaid man, groping blindly amid the mazes of the ultra-microscopic, engaging in bitter and lifelong quarrels over the nephridia of flatworms, waking perhaps one morning to find that someone whose name he has never heard has demolished by a few crucial experiments the work which he had hoped would render him immortal.
Daedalus or Science and the Future (1924), 77.
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I have yet to see any problem, however complicated, which, when you looked at it in the right way, did not become still more complicated.
Quoted in William Thorpe, 'Reduction v. Organicism,' New Scientist, 25 Sep 1969, 43, No 66, 638. In Carl C. Gaither, Statistically Speaking: A Dictionary of Quotations (1996), 187.
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I knew, however, that it would cost ten times what I had available in order to build a molecular beam machine. I decided to follow a byway, rather than the highway. It is a procedure I have subsequently recommended to beginning scientists in this country, where research strategy is best modelled on that used by Wolfe at the Plains of Abraham.
(British General James Wolfe defeated the French defending Quebec in 1759 after scaling a cliff for a surprise attack.)
'A Scientist and the World He Lives In', Speech to the Empire Club of Canada (27 Nov 1986) in C. Frank Turner and Tim Dickson (eds.), The Empire Club of Canada Speeches 1986-1987 (1987), 149-161.

I learned what research was all about as a research student [with] Stoppani ... Max Perutz, and ... Fred Sanger... From them, I always received an unspoken message which in my imagination I translated as “Do good experiments, and don’t worry about the rest.”
From Nobel Lecture (8 Dec 1984), collected in Tore Frängsmyr and ‎Jan Lindsten (eds.), Nobel Lectures in Physiology Or Medicine: 1981-1990 (1993), 268.
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I looked for it [heavy hydrogen, deuterium] because I thought it should exist. I didn't know it would have industrial applications or be the basic for the most powerful weapon ever known [the nuclear bomb] ... I thought maybe my discovery might have the practical value of, say, neon in neon signs.
[He was awarded the 1931 Nobel Prize in Chemistry for discovering deuterium.]
Quoted in 'Moon-Struck Scientist,' New York Times (27 Apr 1961), 42.
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I often say that research is a way of finding out what you are going to do when you can't keep on doing what you are doing now.
'Industrial Prospecting', an address to the Founder Societies of Engineers (20 May 1935). In National Research Council, Reprint and Circular Series of the National Research Council (1933), No. 107, 1.

I ought to say that one of our first joint researches, so far as publication was concerned, had the peculiar effect of freeing me forever from the wiles of college football, and if that is a defect, make the most of it! Dr. Noyes and I conceived an idea on sodium aluminate solutions on the morning of the day of a Princeton-Harvard game (as I recall it) that we had planned to attend. It looked as though a few days' work on freezing-point determinations and electrical conductivities would answer the question. We could not wait, so we gave up the game and stayed in the laboratory. Our experiments were successful. I think that this was the last game I have ever cared about seeing. I mention this as a warning, because this immunity might attack anyone. I find that I still complainingly wonder at the present position of football in American education.
Address upon receiving the Perkin Medal Award, 'The Big Things in Chemistry', The Journal of Industrial and Engineering Chemistry (Feb 1921), 13, No. 2, 162-163.
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I rarely plan my research; it plans me.
'My Commonplace Book', in I Wish I'd Made You Angry Earlier (1998), 314.
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I remember vividly my student days, spending hours at the light microscope, turning endlessly the micrometric screw, and gazing at the blurred boundary which concealed the mysterious ground substance where the secret mechanisms of cell life might be found.
Nobel Lecture, The Coming Age of the Cell, 12 Dec 1974
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I sometimes think about the tower at Pisa as the first particle accelerator, a (nearly) vertical linear accelerator that Galileo used in his studies.
In Leon Lederman and Dick Teresi, The God Particle: If the Universe is the Answer, What is the Question (1993, 2006), 200.
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I strongly oppose cloning, as do most Americans. We recoil at the idea of growing human beings for spare body parts or creating life for our convenience. And while we must devote enormous energy to conquering disease, it is equally important that we pay attention to the moral concerns raised by the new frontier of human embryo stem cell research. Even the most noble ends do not justify any means.
'Address to the Nation on Stem Cell Research', (9 Aug 2001) in Public Papers Of The Presidents Of The United States, George W. Bush, 2001 (2004), Book 2, 955.
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I then began to study arithmetical questions without any great apparent result, and without suspecting that they could have the least connexion with my previous researches. Disgusted at my want of success, I went away to spend a few days at the seaside, and thought of entirely different things. One day, as I was walking on the cliff, the idea came to me, again with the same characteristics of conciseness, suddenness, and immediate certainty, that arithmetical transformations of indefinite ternary quadratic forms are identical with those of non-Euclidian geometry.
Science and Method (1908), trans. Francis Maitland (1914), 53-4.
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I think I have been much of my life an irritant. But some people say that something good came out of my research, something valuable that could be regarded as a pearl, and I can assure those who worked with me it was you who made the pearls and I was merely the grain of sand, the irritant to produce the pearls.
[Recalling how, when increasingly in demand to serve on committees, upon attempting to resign from one, he was told by the chairman 'We want you as an irritant.']
Remark at a luncheon, quoted in Obituary, 'Nicholas Kurti, C. B. E. 14 May 1908-24 November 1998', by J.H. Sanders, Biographical Memoirs of Fellows of the Royal Society (Nov 2000), 46, 309.
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I think it's a very valuable thing for a doctor to learn how to do research, to learn how to approach research, something there isn't time to teach them in medical school. They don't really learn how to approach a problem, and yet diagnosis is a problem; and I think that year spent in research is extremely valuable to them.
On mentoring a medical student.
Quoted in interview by Mary Ellen Avery (1997)
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I think that support of this [stem cell] research is a pro-life pro-family position. This research holds out hope for more than 100 million Americans.
In Eve Herold, George Daley, Stem Cell Wars (2007), 39.
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I told him that for a modern scientist, practicing experimental research, the least that could be said, is that we do not know. But I felt that such a negative answer was only part of the truth. I told him that in this universe in which we live, unbounded in space, infinite in stored energy and, who knows, unlimited in time, the adequate and positive answer, according to my belief, is that this universe may, also, possess infinite potentialities.
Nobel Lecture, The Coming Age of the Cell, 12 Dec 1974

I undertake my scientific research with the confident assumption that the earth follows the laws of nature which God established at creation. ... My studies are performed with the confidence that God will not capriciously confound scientific results by "slipping in" a miracle.
Quoted in Lenny Flank, Deception by Design: The Intelligent Design Movement in America (2007), 81. Also seen as cited from Arthur Newell Strahler, Science and Earth History: the Evolution/Creation Controversy (1987), 40-41.
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I want to stay as close to the edge as I can without going over. Out on the edge you see all kinds of things you can't see from the center.
Player Piano (1999), 84. In Gary William Flake, The Computational Beauty of Nature (2000), 327.
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I was just so interested in what I was doing I could hardly wait to get up in the morning and get at it. One of my friends, a geneticist, said I was a child, because only children can't wait to get up in the morning to get at what they want to do.
Quoted in Evelyn Fox Keller, A Feeling for the Organism: The Life and Work of Barbara McClintock (1984), 70.
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I was unable to devote myself to the learning of this al-jabr [algebra] and the continued concentration upon it, because of obstacles in the vagaries of Time which hindered me; for we have been deprived of all the people of knowledge save for a group, small in number, with many troubles, whose concern in life is to snatch the opportunity, when Time is asleep, to devote themselves meanwhile to the investigation and perfection of a science; for the majority of people who imitate philosophers confuse the true with the false, and they do nothing but deceive and pretend knowledge, and they do not use what they know of the sciences except for base and material purposes; and if they see a certain person seeking for the right and preferring the truth, doing his best to refute the false and untrue and leaving aside hypocrisy and deceit, they make a fool of him and mock him.
A. P. Youschkevitch and B. A. Rosenfeld, 'Al-Khayyami', in C. C. Gillispie (ed.), Dictionary of Scientific Biography (1973), Vol. 7, 324.
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I went to the trash pile at Tuskegee Institute and started my laboratory with bottles, old fruit jars and any other thing I found I could use. ... [The early efforts were] worked out almost wholly on top of my flat topped writing desk and with teacups, glasses, bottles and reagents I made myself.
Manuscript fragment, no date, Box 1, George Washington Carver Papers. Cited in Linda O. McMurry, George Washington Carver, Scientist and Symbol (1982), 130.
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I will frankly tell you that my experience in prolonged scientific investigations convinces me that a belief in God—a God who is behind and within the chaos of vanishing points of human knowledge—adds a wonderful stimulus to the man who attempts to penetrate into the regions of the unknown.
As quoted in E.P. Whipple, 'Recollections of Agassiz', in Henry Mills Alden (ed.), Harper's New Monthly Magazine (June 1879), 59, 103.
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If a little less time was devoted to the translation of letters by Julius Caesar describing Britain 2000 years ago and a little more time was spent on teaching children how to describe (in simple modern English) the method whereby ethylene was converted into polythene in 1933 in the ICI laboratories at Northwich, and to discussing the enormous social changes which have resulted from this discovery, then I believe that we should be training future leaders in this country to face the world of tomorrow far more effectively than we are at the present time.
Quoted in an Obituary, D. P. Craig, Biographical Memoirs of Fellows of the Royal Society (1972), 18, 461.
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If a mathematician wishes to disparage the work of one of his colleagues, say, A, the most effective method he finds for doing this is to ask where the results can be applied. The hard pressed man, with his back against the wall, finally unearths the researches of another mathematician B as the locus of the application of his own results. If next B is plagued with a similar question, he will refer to another mathematician C. After a few steps of this kind we find ourselves referred back to the researches of A, and in this way the chain closes.
From final remarks in 'The Semantic Conception of Truth and the Foundations of Semantics' (1944), collected in Leonard Linsky (ed.), Semantics and the Philosophy of Language: A Collection of Readings (1952), 41.
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If a research project is not worth doing at all, it is not worth doing properly.
Anonymous
Saying.

If any student comes to me and says he wants to be useful to mankind and go into research to alleviate human suffering, I advise him to go into charity instead. Research wants real egotists who seek their own pleasure and satisfaction, but find it in solving the puzzles of nature.
In Science Today (May 1980), 35. In Vladimir Burdyuzha, The Future of Life and the Future of Our Civilization (2006), 374.
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If at first you don’t succeed, try, try, try again.
Anonymous
Old saying.
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If I go out into nature, into the unknown, to the fringes of knowledge, everything seems mixed up and contradictory, illogical, and incoherent. This is what research does; it smooths out contradictions and makes things simple, logical, and coherent.
In 'Dionysians and Apollonians', Science (2 Jun 1972), 176, 966. Reprinted in Mary Ritchie Key, The Relationship of Verbal and Nonverbal Communication (1980), 318.
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If I want to stop a research program I can always do it by getting a few experts to sit in on the subject, because they know right away that it was a fool thing to try in the first place.
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If it is impossible to judge merit and guilt in the field of natural science, then it is not possible in any field, and historical research becomes an idle, empty activity.
Reden und Abhandlungen (1874). Trans. W. H. Brock.
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If Louis Pasteur were to come out of his grave because he heard that the cure for cancer still had not been found, NIH would tell him, “Of course we'll give you assistance. Now write up exactly what you will be doing during the three years of your grant.” Pasteur would say, “Thank you very much,” and would go back to his grave. Why? Because research means going into the unknown. If you know what you are going to do in science, then you are stupid! This is like telling Michelangelo or Renoir that he must tell you in advance how many reds and how many blues he will buy, and exactly how he will put those colors together.
Interview for Saturday Evening Post (Jan/Feb 1981), 30.
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If one in twenty does not seem high enough odds, we may, if we prefer it, draw the line at one in fifty (the 2 per cent. point), or one in a hundred (the 1 per cent. point). Personally, the writer prefers to set a low standard of significance at the 5 per cent. point, and ignore entirely all results which fail to reach this level. A scientific fact should be regarded as experimentally established only if a properly designed experiment rarely fails to give this level of significance.
'The Arrangement of Field Experiments', The Journal of the Ministry of Agriculture, 1926, 33, 504.
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If one were not animated with the desire to discover laws, they would escape the most enlightened attention.
Maurice Crosland, Gay-Lussac, Scientist and Bourgeois (1978), 54.
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If politics is the art of the possible, research is surely the art of the soluble. Both are immensely practical-minded affairs.
The Art of the Soluble (1969), 97. Quoted in Colin J. Sanderson, Understanding Genes and GMOs (2007), 1.

If the juices of the body were more chymically examined, especially by a naturalist, that knows the ways of making fixed bodies volatile, and volatile fixed, and knows the power of the open air in promoting the former of those operations; it is not improbable, that both many things relating to the nature of the humours, and to the ways of sweetening, actuating, and otherwise altering them, may be detected, and the importance of such discoveries may be discerned.
Quoted In Barbara Kaplan (ed.) Divulging of Useful Truths in Physick: The Medical Agenda of Robert Boyle (1993), 92.
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If there is no solace in the fruits of our research, there is at least some consolation in the research itself. Men and women are not content to comfort themselves with tales of gods and giants, or to confine their thoughts to the daily affairs of life; they also build telescopes and satellites and accelerators and sit at their desks for endless hours working out the meaning of the data they gather.
In The First Three Minutes (1977), 154-155.
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If we knew what we were doing, it wouldn't be research.
Anonymous
Although seen in various publications attributed but without citation to Albert Einstein, Webmaster is doubtful, and is placing it under Anonymous. But, if you know the primary print source, perhaps in different wording, please contact the Webmaster.
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If you have built castles in the air, your work need not be lost; that is where they should be. Now put the foundations under them.
In last chapter 'Conclusion', from Walden: or, Life in the Woods (1854), collected in The Writings of Henry David Thoreau (1894), Vol. 2, 499.
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If you want to really understand about a tumor, you've got be be a tumor.
Quoted in Evelyn Fox Keller, A Feeling for the Organism: The Life and Work of Barbara McClintock (1984), 207.
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In 1944 Erwin Schroedinger, stimulated intellectually by Max Delbruck, published a little book called What is life? It was an inspiration to the first of the molecular biologists, and has been, along with Delbruck himself, credited for directing the research during the next decade that solved the mystery of how 'like begat like.' Max was awarded this Prize in 1969, and rejoicing in it, he also lamented that the work for which he was honored before all the peoples of the world was not something which he felt he could share with more than a handful. Samuel Beckett's contributions to literature, being honored at the same time, seemed to Max somehow universally accessible to anyone. But not his. In his lecture here Max imagined his imprisonment in an ivory tower of science.
'The Polymerase Chain Reaction', Nobel Lecture (8 Dec 1993). In Nobel Lectures: Chemistry 1991-1995 (1997), 103.
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In my considered opinion the peer review system, in which proposals rather than proposers are reviewed, is the greatest disaster visited upon the scientific community in this century. No group of peers would have approved my building the 72-inch bubble chamber. Even Ernest Lawrence told me he thought I was making a big mistake. He supported me because he knew my track record was good. I believe that U.S. science could recover from the stultifying effects of decades of misguided peer reviewing if we returned to the tried-and-true method of evaluating experimenters rather than experimental proposals. Many people will say that my ideas are elitist, and I certainly agree. The alternative is the egalitarianism that we now practice and I've seen nearly kill basic science in the USSR and in the People's Republic of China.
Alvarez: Adventures of a Physicist (1987), 200-1.
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In my work I now have the comfortable feeling that I am so to speak on my own ground and territory and almost certainly not competing in an anxious race and that I shall not suddenly read in the literature that someone else had done it all long ago. It is really at this point that the pleasure of research begins, when one is, so to speak, alone with nature and no longer worries about human opinions, views and demands. To put it in a way that is more learned than clear: the philological aspect drops out and only the philosophical remains.
In Davis Baird, R.I.G. Hughes and Alfred Nordmann, Heinrich Hertz: Classical Physicist, Modern Philosopher (1998), 157.
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In the beginning the gods did not at all reveal all things clearly to mortals, but by searching men in the course of time find them out better.
Quoted in Arthur Fairbanks (ed. And trans.), The First Philosophers of Greece (1898), 71, fragment 16.

In the distant future I see open fields for far more important researches. Psychology will be based on a new foundation, that of the necessary acquirement of each mental power and capacity by gradation. Light will be thrown on the origin of man and his history.
On The Origin of Species by Means of Natural Selection (1859, 1882), 428 .
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In the study of this membrane [the retina] I for the first time felt my faith in Darwinism (hypothesis of natural selection) weakened, being amazed and confounded by the supreme constructive ingenuity revealed not only in the retina and in the dioptric apparatus of the vertebrates but even in the meanest insect eye. ... I felt more profoundly than in any other subject of study the shuddering sensation of the unfathomable mystery of life.
Recollections of My Life (1898), 576. Quoted in Sidney Perkowitz, Empire of Light (1999), 16.
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In the twenties the late Dr. Glenn Frank, an eminent social scientist, developed a new statement of the scientific code, which has been referred to as the “Five Fingers of the Scientific Method.” It may be outlined as follows: find the facts; filter the facts; focus the facts; face the facts; follow the facts. The facts or truths are found by experimentation; the motivation is material. The facts are filtered by research into the literature; the motivation is material. The facts are focused by the publication of results; again the motivation is material. Thus the first three-fifths of the scientific method have a material motivation. It is about time scientists acknowledge that there is more to the scientific convention than the material aspect. Returning to the fourth and fifth fingers of Dr. Frank's conception of the scientific method, the facts should be faced by the proper interpretation of them for society. In other words, a scientist must assume social responsibility for his discoveries, which means that he must have a moral motivation. Finally, in the fifth definition of the scientific method, the facts are to be followed by their proper application to everyday life in society, which means moral motivation through responsibility to society.
From 'Scientists and Society', American Scientist (Jul 1954), 42, No. 3, 495.
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In these strenuous times, we are likely to become morbid and look constantly on the dark side of life, and spend entirely too much time considering and brooding over what we can't do, rather than what we can do, and instead of growing morose and despondent over opportunities either real or imaginary that are shut from us, let us rejoice at the many unexplored fields in which there is unlimited fame and fortune to the successful explorer and upon which there is no color line; simply the survival of the fittest.
[In article urging blacks to engage in plant breeding to develop improved species.]
'A New Industry for Colored Men and Women', Colored American (Jan 1908, 14, 33. Cited in Linda O. McMurry, George Washington Carver, Scientist and Symbol (1982), 109.
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Infectious disease is one of the few genuine adventures left in the world. The dragons are all dead and the lance grows rusty in the chimney corner. ... About the only sporting proposition that remains unimpaired by the relentless domestication of a once free-living human species is the war against those ferocious little fellow creatures, which lurk in dark corners and stalk us in the bodies of rats, mice and all kinds of domestic animals; which fly and crawl with the insects, and waylay us in our food and drink and even in our love
Rats, Lice and History (1935)
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It can happen to but few philosophers, and but at distant intervals, to snatch a science, like Dalton, from the chaos of indefinite combination, and binding it in the chains of number, to exalt it to rank amongst the exact. Triumphs like these are necessarily 'few and far between.'
Reflections on the Decline of Science in England (1830), 22.
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It is a curious property of research activity that after the problem has been solved the solution seems obvious. This is true not only for those who have not previously been acquainted with the problem, but also for those who have worked over it for years.
Address at the Franklin Institute (1937). Journal of the Franklin Institute (1937), 224, 277. Also see Paul C. Wensberg, Land's Polaroid: A Company and the Man who Invented It (1987), 31.
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It is a good morning exercise for a research scientist to discard a pet hypothesis every day before breakfast. It keeps him young.
On Aggression, trans. M. Latzke (1966), 8.
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It is a right, yes a duty, to search in cautious manner for the numbers, sizes, and weights, the norms for everything [God] has created. For He himself has let man take part in the knowledge of these things ... For these secrets are not of the kind whose research should be forbidden; rather they are set before our eyes like a mirror so that by examining them we observe to some extent the goodness and wisdom of the Creator.
Epitome of Copernican Astronomy. In Michael B. Foster, Mystery and Philosophy, 61. Cited by Max Casper and Doris Hellman, trans., ed. Kepler (1954), 381. Cited by Gerald J. Galgan, Interpreting the Present: Six Philosophical Essays (1993), 105. Gerald J. Galgan
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It is idle to expect any great advancement in science from the superinducing and engrafting of new things upon old. We must begin anew from the very foundations, unless we would revolve for ever in a circle with mean and contemptible progress.
The New Organon (1620) in James Spedding, Robert Ellis and Douglas Heath (eds.), The Works of Francis Bacon (1887-1901), Vol. 4, 52.

It is sometimes said that scientists are unromantic, that their passion to figure out robs the world of beauty and mystery. But is it not stirring to understand how the world actually works—that white light is made of colors, that color is the way we perceive the wavelengths of light, that transparent air reflects light, that in so doing it discriminates among the waves, and that the sky is blue for the same reason that the sunset is red? It does no harm to the romance of the sunset to know a little bit about it.
Pale Blue Dot: A Vision of the Human Future in Space (1994), 159.
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It is terrifying to think how much research is needed to determine the truth of even the most unimportant fact.
Attributed.
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It may be said “In research, if you know what you are doing, then you shouldn't be doing it.” In a sense, if the answer turns out to be exactly what you expected, then you have learned nothing new, although you may have had your confidence increased somewhat.
In Numerical Methods for Scientists and Engineers (1973), 704.
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It never occurred to me that there was going to be any stumbling block. Not that I had the answer, but [I had] the joy of going at it. When you have that joy, you do the right experiments. You let the material tell you where to go, and it tells you at every step what the next has to be because you're integrating with an overall brand new pattern in mind.
When asked how she could have worked for two years without knowing the outcome.
Quoted in Evelyn Fox Keller, A Feeling for the Organism: The Life and Work of Barbara McClintock (1984), 125.
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It takes a trained and discerning researcher to keep the goal in sight, and to detect evidence of the creeping progress toward it.
from a speech to the Empire Club of Canada (27 Nov 1986)
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It was basic research in the photoelectric field—in the photoelectric effect that would one day lead to solar panels. It was basic research in physics that would eventually produce the CAT scan. The calculations of today's GPS satellites are based on the equations that Einstein put to paper more than a century ago.
Speech to the National Academy of Sciences Annual Meeting (27 Apr 2009).
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It was eerie. I saw myself in that machine. I never thought my work would come to this.
Upon seeing a distorted image of his face, reflected on the inside cylindrical surface of the bore while inside an MRI (magnetic-resonance-imaging) machine—a device made possible by his early physical researches on nuclear magnetic resonance (1938).
Quoted from conversation with the author, John S. Rigden, in Rabi, Scientist and Citizen (2000), xxii. Rabi was recalling having an MRI, in late 1987, a few months before his death. He had been awarded the Nobel Prize in 1944, for his discovery of the magnetic resonance method.
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It will be contributing to bring forward the moment in which, seeing clearer into the nature of things, and having learnt to distinguish real knowledge from what has only the appearance of it, we shall be led to seek for exactness in every thing.
'An Essay on Pyrometry and Areometry, and on Physical Measures in General', Philosophical Transactions, 1778, 68, 493.
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Keep on going and the chances are you will stumble on something, perhaps when you are least expecting it. I have never heard of anyone stumbling on something sitting down.

Kohn's Second Law: An experiment is reproducible until another laboratory tries to repeat it
In Dr. N Sreedharan, Quotations of Wit and Wisdom (2007), 24
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Lubin's Law: If another scientist thought your research was more important than his, he would drop what he is doing and do what you are doing.
Anonymous
In Dr. N Sreedharan, Quotations of Wit and Wisdom (2007), 68.

Man is not born to solve the problem of the universe, but to find out where the problem begins and then restrain himself within the limits of the comprehensible.
The Homiletic Review, Vol. 83-84 (1922), Vol. 84, 290.
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Many of the things that have happened in the laboratory have happened in ways it would have been impossible to foresee, but not impossible to plan for in a sense. I do not think Dr. Whitney deliberately plans his serendipity but he is built that way; he has the art—an instinctive way of preparing himself by his curiosity and by his interest in people and in all kinds of things and in nature, so that the things he learns react on one another and thereby accomplish things that would be impossible to foresee and plan.
Quoted in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 355.
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Modern physics has changed nothing in the great classical disciplines of, for instance, mechanics, optics, and heat. Only the conception of hitherto unexplored regions, formed prematurely from a knowledge of only certain parts of the world, has undergone a decisive transformation. This conception, however, is always decisive for the future course of research.
In Philosophical Problems of Nuclear Science: Eight Lectures (1952), 18.
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Modern theories did not arise from revolutionary ideas which have been, so to speak, introduced into the exact sciences from without. On the contrary they have forced their way into research which was attempting consistently to carry out the programme of classical physics—they arise out of its very nature. It is for this reason that the beginnings of modern physics cannot be compared with the great upheavals of previous periods like the achievements of Copernicus. Copernicus’s idea was much more an import from outside into the concepts of the science of his time, and therefore caused far more telling changes in science than the ideas of modern physics are creating to-day.
In Philosophical Problems of Nuclear Science: Eight Lectures (1952), 13.
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More and more of out colleagues fail to understand our work because of the high specialization of research problems. We must not be discouraged if the products of our labor are not read or even known to exist. The joy of research must be found in doing since every other harvest is uncertain.
Letter to Dr. E. B. Krumhaar (11 Oct 1933), in Journal of Bacteriology (Jan 1934), 27, No. 1, 20.
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Most of the knowledge and much of the genius of the research worker lie behind his selection of what is worth observing. It is a crucial choice, often determining the success or failure of months of work, often differentiating the brilliant discoverer from an otherwise admirable but entirely unproductive plodder.
The Furtherance of Medical Research (1941), 8.

Most of us who become experimental physicists do so for two reasons; we love the tools of physics because to us they have intrinsic beauty, and we dream of finding new secrets of nature as important and as exciting as those uncovered by our scientific heroes. But we walk a narrow path with pitfalls on either side. If we spend all our time developing equipment, we risk the appellation of “plumber,” and if we merely use the tools developed by others, we risk the censure of our peers for being parasitic.
'Recent Developments in Particle Physics', Nobel Lecture, December l1th, 1968. In Nobel Lectures: Physics 1963-1970 (1972), 24I.
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Much of the work we do as scientists involves filling in the details about matters that are basically understood already, or applying standard techniques to new specific cases. But occasionally there is a question that offers an opportunity for a really major discovery.
In Tyrannosaurus Rex and the Crater of Doom (1997), 42.
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My ambition was to bring to bear on medicine a chemical approach. I did that by chemical manipulation of viruses and chemical ways of thinking in biomedical research.
From interview (1980) quoted in New York Times (24 Jun 1995), 9.
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My decision to begin research in radio astronomy was influenced both by my wartime experience with electronics and antennas and by one of my teachers, Jack Ratcliffe, who had given an excellent course on electromagnetic theory during my final undergraduate year.
From Autobiography in Wilhelm Odelberg (ed.), Les Prix Nobel en 1974/Nobel Lectures (1975)
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My observations of the young physicists who seem to be most like me and the friends I describe in this book tell me that they feel as we would if we had been chained to those same oars. Our young counterparts aren't going into nuclear or particle physics (they tell me it's too unattractive); they are going into condensed-matter physics, low-temperature physics, or astrophysics, where important work can still be done in teams smaller than ten and where everyone can feel that he has made an important contribution to the success of the experiment that every other member of the collaboration is aware of. Most of us do physics because it's fun and because we gain a certain respect in the eyes of those who know what we've done. Both of those rewards seem to me to be missing in the huge collaborations that now infest the world of particle physics.
Alvarez: Adventures of a Physicist (1987), 198.
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My sense is that the most under-appreciated–and perhaps most under-researched–linkages between forests and food security are the roles that forest-based ecosystem services play in underpinning sustainable agricultural production. Forests regulate hydrological services including the quantity, quality, and timing of water available for irrigation. Forest-based bats and bees pollinate crops. Forests mitigate impacts of climate change and extreme weather events at the landscape scale.
In 'Forests and food security: What we know and need to know', Forest News online blog by the Center for International Forestry Research (20 Apr 2011).
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Nature is full of by-ends. A moth feeds on a petal, in a moment the pollen caught on its breast will be wedding this blossom to another in the next county.
From chapter 'Jottings from a Note-Book', in Canadian Stories (1918), 170.
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Necessity is not the mother of invention. Knowledge and experiment are its parents. It sometimes happens that successful search is made for unknown materials to fill well-recognized and predetermined requirements. It more often happens that the acquirement of knowledge of the previously unknown properties of a material suggests its trial for some new use. These facts strongly indicate the value of knowledge of properties of materials and indicate a way for research.
Quoted in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 357.
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No aphorism is more frequently repeated in connection with field trials, than that we must ask Nature few questions, or, ideally, one question, at a time. The writer is convinced that this view is wholly mistaken. Nature, he suggests, will best respond to a logical and carefully thought out questionnaire; indeed, if we ask her a single question, she will often refuse to answer until some other topic has been discussed.
'The Arrangement of Field Experiments', The Journal of the Ministry of Agriculture, 1926, 33, 511.
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No generalizing beyond the data, no theory. No theory, no insight. And if no insight, why do research.
'Developing Theory About the Development of Theory,' in Ken G. Smith and Michael A. Hitt, Great Minds in Management: the Theory of Process Development (2005), 361.
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No gun is perfectly true. So the marksman, that he may hit the bull's-eye, points elsewhere.
From chapter 'Jottings from a Note-Book', in Canadian Stories (1918), 169.
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No occupation is more worthy of an intelligent and enlightened mind, than the study of Nature and natural objects; and whether we labour to investigate the structure and function of the human system, whether we direct our attention to the classification and habits of the animal kingdom, or prosecute our researches in the more pleasing and varied field of vegetable life, we shall constantly find some new object to attract our attention, some fresh beauties to excite our imagination, and some previously undiscovered source of gratification and delight.
In A Practical Treatise on the Cultivation of the Dahlia (1838), 1-2.
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No politics, no committees, no reports, no referees, no interviews – just highly motivated people picked by a few men of good judgment.
[Describing the compelling ideas of Max Perutz on how best to nurture research.]
Quoted in Andrew Jack, "An Acute Talent for Innovation", Financial Times (1 Feb 2009).
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No research will answer all queries that the future may raise. It is wiser to praise the work for what it has accomplished and then to formulate the problems still to be solved.
Letter to Dr. E. B. Krumhaar (11 Oct 1933), in Journal of Bacteriology (Jan 1934), 27, No. 1, 19.
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None of the great discoveries was made by a 'specialist' or a 'researcher'.
Martin H. Fischer, Howard Fabing (ed.) and Ray Marr (ed.), Fischerisms (1944).
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Nothing has such power to broaden the mind as the ability to investigate systematically and truly all that comes under thy observation in life.
Meditations. In Jehiel Keeler Hoyt, The Cyclopedia of Practical Quotations (1896), 326.
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Now, the causes being four, it is the business of the student of nature to know about them all, and if he refers his problems back to all of them, he will assign the “why” in the way proper to his science—the matter, the form, the mover, that for the sake of which.
Aristotle
Physics, 198a, 22-4. In Jonathan Barnes (ed.), The Complete Works of Aristotle (1984), Vol. I, 338.
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Obervation is a passive science, experimentation is an active science.
In Fielding Hudson Garrison, An Introduction to the History of Medicine (1929), 15.
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Oh, most magnificent and noble Nature!
Have I not worshipped thee with such a love
As never mortal man before displayed?
Adored thee in thy majesty of visible creation,
And searched into thy hidden and mysterious ways
As Poet, as Philosopher, as Sage?
A late fragment, probably written when he knew he was dying, in Fragmentary Remains (1858), 14.
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Once human beings realize something can be done, they're not satisfied until they've done it.
Cease Fire (1958). In Gary Westfahl, Science Fiction Quotations: From the Inner Mind to the Outer Limits (2006), 1.
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One and all
We lend an ear—nay, Science takes thereto—
Encourages the meanest who has racked
Nature until he gains from her some fact,
To state what truth is from his point of view,
Mere pin-point though it be: since many such
Conduce to make a whole, she bids our friend
Come forward unabashed and haply lend
His little life-experience to our much
Of modern knowledge.
'With Francis Furini', The Complete Poetic and Dramatic Works of Robert Browning (1895), 967.
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One major problem with any science is that people who don't know the conceptual history of their field go round re-inventing the elliptical wheel.
Telephone conversation with Susan Abrams 1983.
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Our children will enjoy in their homes electrical energy too cheap to meter. ... Transmutation of the elements, unlimited power, ability to investigate the working of living cells by tracer atoms, the secret of photosynthesis about to be uncovered, these and a host of other results, all in about fifteen short years. It is not too much to expect that our children will know of great periodic famines in the world only as matters of history, will travel effortlessly over the seas and under the and through the air with a minimum of danger and at great speeds, and will experience a life span far longer than ours, as disease yields and man comes to understand what causes him to age.
Speech at the 20th anniversary of the National Association of Science Writers, New York City (16 Sep 1954), asquoted in 'Abundant Power From Atom Seen', New York Times (17 Sep 1954) 5.
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Our novice runs the risk of failure without additional traits: a strong inclination toward originality, a taste for research, and a desire to experience the incomparable gratification associated with the act of discovery itself.
In Santiago Ramón y Cajal, Neely Swanson (trans.) and Larry W. Swanson (trans.), Advice for a Young Investigator (2004), 48.
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Our scientific work in physics consists in asking questions about nature in the language that we possess and trying to get an answer from experiment by the means at our disposal. In this way quantum theory reminds us, as Bohr has put it, of the old wisdom that when searching for harmony in life one must never forget that in the drama of existence we are ourselves both players and spectators. It is understandable that in our scientific relation to nature our own activity becomes very important when we have to deal with parts of nature into which we can penetrate only by using the most elaborate tools.
The Copenhagen Interpretation of Quantum Theory (1958). In Steve Adams, Frontiers (2000), 13.
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Paradoxical as it may at first appear, the fact is that, as W. H. George has said, scientific research is an art, not a science.
The Art of Scientific Investigation (1950, 1957), 138.
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Parkinson's Law is a purely scientific discovery, inapplicable except in theory to the politics of the day. It is not the business of the botanist to eradicate the weeds. Enough for him if he can tell us just how fast they grow.
Parkinson's Law or the Pursuit of Progress (1958), 15.
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People have noted with admiration how the progress of scientific enquiry is like the growth of a coral reef; each generation of little toilers building a sure foundation on which their successors may build yet further. The simile is apt in many ways, and in one way in particular that is worth considering. When we see how industrious and how prolific are the coral insects, our chief astonishment should be, not how vast are the structures they have built, but how few and scattered. Why is not every coast lined with coral? Why is the abyss if ocean not bridged with it. The answer is that coral only lives under certain limitations; it can only thrive at certain depths, in water of certain temperatures and salinities; outside these limits it languishes and dies. Science is like coral in this. Scientific investigators can only work in certain spots of the ocean of Being, where they are at home, and all outside is unknown to them...
Scientific Method: An Inquiry into the Character and Validy of Natural Law (1923), 195. Quoted in Wilson Gee, Social science research methods (1950), 182.
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People who are unused to learning, learn little, and that slowly, while those more accustomed do much more and do it more easily. The same thing also happens in connection with research. Those who are altogether unfamiliar with this become blinded and bewildered as soon as their minds begin to work: they readily withdraw from the inquiry, in a state of mental fatigue and exhaustion, much like people who attempt to race without having been trained. He, on the other hand, who is accustomed to research, seeks and penetrates everywhere mentally, passing constantly from one topic to another; nor does he ever give up his investigation; he pursues it not merely for a matter of days, but throughout his whole life. Also by transferring his mind to other ideas which are yet not foreign to the questions at issue, he persists till he reaches the solution.
'On Paralysis'. Quoted in A. J. Brock, Greek Medicine: Being Extracts Illustrative of Medical Writers from Hippocrates to Galen (1929), 185.

Progress in science depends on new techniques, new discoveries and new ideas, probably in that order.
Attributed.
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Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
'What the Doctor Ordered&#-30;, Time (18 Aug 1952)
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Research cannot be forced very much. There is always danger of too much foliage and too little fruit.
Letter to Professor Simon H. Gage. Quoted in Paul Franklin Clark, 'Theobald Smith, Student of Disease (1859-1934)', Journal of the History of Medicine and Allied Sciences (1959), 14, 492.
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Research has been called good business, a necessity, a gamble, a game. It is none of these—it's a state of mind.
Martin H. Fischer, Howard Fabing (ed.) and Ray Marr (ed.), Fischerisms (1944).
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Research has deserted the individual and entered the group. The individual worker find the problem too large, not too difficult. He must learn to work with others.
Letter to Dr. E. B. Krumhaar (11 Oct 1933), in Journal of Bacteriology (Jan 1934), 27, No. 1, 20.
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Research is an organized method for keeping you reasonably dissatisfied with what you have.

Research is appreciation.
From 'The Biggest Things in Chemistry', The Journal of Industrial and Engineering Chemistry (Feb 1921), 13, No. 2, 165.
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Research is formalized curiosity. It is poking and prying with a purpose.
Zora Neale Hurston, Robert Hemenway, Dust Tracks on a Road: an Autobiography (1984), 174.
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Research is four things: brains with which to think, eyes with which to see, machines with which to measure, and fourth, money.
Quoted in obituary, 'Albert Szent-Gyorgyi Dead; Research Isolated Vitamin C''. Walter Sullivan, New York Times (25 Oct 1986), 9.
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Research is industrial prospecting. The oil prospectors use every scientific means to find new paying wells. Oil is found by each one of a number of methods. My own group of men are prospecting in a different field, using every possible scientific means. We believe there are still things left to be discovered. We have only stumbled upon a few barrels of physical laws from the great pool of knowledge. Some day we are going to hit a gusher.
'Industrial Prospecting', an address to the Founder Societies of Engineers (20 May 1935). In National Research Council, Reprint and Circular Series of the National Research Council (1933), No. 107, 1.
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Research is the art of seeing what everyone else has seen, and doing what no-one else has done.
Anonymous
In Barbara A. Nadel (ed.), Building Security (2004), 18.1. Compare quote by Albert Szent-Gyorgyi: 'Discovery consists of seeing what everybody has seen and thinking what nobody has thought.'
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Research is the name given the crystal formed when the night's worry is added to the day's sweat.
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Research is the process of going up alleys to see if they are blind.
The Nature of Natural History (1950)

Research is to see what everybody has seen and think what nobody has thought.
Bioenergetics (1957), 57.
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Research serves to make building stones out of stumbling blocks.
Quoted in Massachusetts Institute of Technology, Technology Review (1932), 34, 4.
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Research under a paradigm must be a particularly effective way of inducing paradigm change.
The Structure of Scientific Revolutions (1962), 52.
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Science emerges from the other progressive activities of man to the extent that new concepts arise from experiments and observations, and that the new concepts in turn lead to further experiments and observations.
as quoted by Marshall Bates in The Nature of Natural History (1950), p.4
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Science is not a sacred cow—but there are a large number of would-be sacred cowherds busily devoting quantities of time, energy and effort to the task of making it one, so they can be sacred cowherds.
Introduction to Prologue to Analog (1962)
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Science is best defined as a careful, disciplined, logical search for knowledge about any and all aspects of the universe, obtained by examination of the best available evidence and always subject to correction and improvement upon discovery of better evidence. What's left is magic. And it doesn't work.
The Mask of Nostradamus: The Prophecies of the World's Most Famous Seer (1993), 66.
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Science is the topography of ignorance. From a few elevated points we triangulate vast spaces, inclosing infinite unknown details. We cast the lead, and draw up a little sand from abysses we may never reach with our dredges.
'Border Lines of Knowledge in Some Provinces of Medical Science', an introductory lecture to the Medical Class of Harvard University (6 Nov 1861). In Works of Oliver Wendell Holmes (1892), 211.
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Science knows no politics. Are we in this frenzy of [the Depression] economy, brought about by those who control the wealth of this country, seeking to put a barrier on science and research for the paltry sum of $39,113 out of an appropriation of $100,000,000?
Speaking (28 Dec 1932) as a member of the 72nd Congress, early in the Great Depression, in opposition to an attempt to eliminate a small amount from the agricultural appropriation bill. As quoted in 'Mayor-Elect La Guardia on Research', Science (1933), New Series, 78, No. 2031, 510-511. Also in A. Hunter Dupree, under subtitle 'Impact of the Great Depression' in Science in the Federal Government: A History of Policies and Activities to 1940, 344.
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Science, my boy, is composed of errors, but errors that it is right to make, for they lead step by step to the truth.
Journey to the Centre of the Earth, translated by William Butcher (1992, 2008), 146.
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Scientific research is based on the idea that everything that takes place is determined by laws of nature, and therefore this holds for the actions of people. For this reason, a research scientist will hardly be inclined to believe that events could be influenced by a prayer, ie by a wish addressed to a supernatural Being.
However, it must be admitted that our actual knowledge of these laws is only imperfect and fragmentary, so that, actually, the belief in the existence of basic all-embracing laws in Nature also rests on a sort of faith. All the same this faith has been largely justified so far by the success of scientific research.
Letter (24 Jan 1936) replying to a a letter (19 Jan 1936) asking if scientists pray, from a child in the sixth grade in a Sunday School in New York City. In Albert Einstein, Helen Dukas (ed.) and Banesh Hoffmann (ed.), Albert Einstein, The Human Side (1981), 32-33.
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Scientific research is not itself a science; it is still an art or craft.
In The Scientist in Action: A Scientific Study of His Methods (1938), 29.
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Scientific research was much like prospecting: you went out and you hunted, armed with your maps and instruments, but in the ened your preparations did not matter, or even your intuition. You needed your luck, and whatever benefits accrued to the diligent, through sheer, grinding hard work.
The Andromeda Strain (1969)
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Scientific training gives its votaries freedom from the impositions of modern quackery. Those who know nothing of the laws and processes of Nature fall an easy prey to quacks and impostors. Perfectionism in the realm of religion; a score of frauds in the realm of medicine, as electric shoe soles, hair brushes and belts, electropises, oxydonors, insulating bed casters, and the like; Christian science. In the presence of whose unspeakable stillness and self-stultifying idealism a wise man knows not whether to laugh or cry; Prof. Weltmer's magnetic treatment of disease; divine healing and miracle working by long-haired peripatetics—these and a score of other contagious fads and rank impostures find their followers among those who have no scientific training. Among their deluded victims are thousands of men and women of high character, undoubted piety, good intentions, charitable impulses and literary culture, but none trained to scientific research. Vaccinate the general public with scientific training and these epidemics will become a thing of the past.
As quoted by S.D. Van Meter, Chairman, closing remarks for 'Report of Committee on Public Policy and Legislation', to the Colorado State Medical Society in Denver, printed in Colorado Medicine (Oct 1904), 1, No. 12, 363. Van Meter used the quote following his statement, “In conclusion, allow me to urge once more the necessity of education of the public as well as the profession if we ever expect to correct the evils we are striving to reach by State and Society legislation. Much can be accomplished toward this end by the publication of well edited articles in the secular press upon medical subjects the public is eager to know about.” Prof. Weitmer is presumably Sidney A. Weltmer, founder of The Weltmer Institute of Suggestive Therapeutics, who offered a Course in Magnetic Healing by mail order correspondance (1899).
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Scientists alone can establish the objectives of their research, but society, in extending support to science, must take account of its own needs. As a layman, I can suggest only with diffidence what some of the major tasks might be on your scientific agenda, but ... First, I would suggest the question of the conservation and development of our natural resources. In a recent speech to the General Assembly of the United Nations, I proposed a world-wide program to protect land and water, forests and wildlife, to combat exhaustion and erosion, to stop the contamination of water and air by industrial as well as nuclear pollution, and to provide for the steady renewal and expansion of the natural bases of life.
From Address to the Centennial Convocation of the National Academy of Sciences (22 Oct 1963), 'A Century of Scientific Conquest'. Online at The American Presidency Project.
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Scientists tend to resist interdisciplinary inquiries into their own territory. In many instances, such parochialism is founded on the fear that intrusion from other disciplines would compete unfairly for limited financial resources and thus diminish their own opportunity for research.
[Naming territorial dominance, greed, and fear of the unknown, as some of the influences on the increasing specialization of science]
Quoted in Anthony L. Peratt, 'Dean of the Plasma Dissidents', Washington Times, supplement: The World and I (May 1988),192.
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Scientists who dislike constraints on research like to remark that a truly great research worker needs only three pieces of equipment: a pencil, a pieve of paper and a brain. But they quote this maxim more often at academic banquets than at budget hearings.
In Dr. N Sreedharan, Quotations of Wit and Wisdom (2007), 68.
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Scientists, therefore, are responsible for their research, not only intellectually but also morally. This responsibility has become an important issue in many of today's sciences, but especially so in physics, in which the results of quantum mechanics and relativity theory have opened up two very different paths for physicists to pursue. They may lead us - to put it in extreme terms - to the Buddha or to the Bomb, and it is up to each of us to decide which path to take.
The Turning Point: Science, Society, and the Rising Culture (1983), 87.
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Sex is the best form of fusion at room temperature.
Anonymous
Saying.
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She is a reflection of comfortable middle-class values that do not take seriously the continuing unemployment. What I particularly regret is that she does not take seriously the intellectual decline. Having given up the Empire and the mass production of industrial goods, Britain's future lay in its scientific and artistic pre-eminence. Mrs Thatcher will be long remembered for the damage she has done.
On Mrs Margaret H. Thatcher.
The Guardian, 15 Oct 1988.
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Somewhere, something incredible is waiting to be known.
In Larry Chang, Wisdom for the Soul: Five Millennia of Prescriptions for Spiritual Healing (2006), 561, but without source reference. Although widely seen, webmaster has found no authoritative reference or primary print source for its origin. Can you help?

Success in research needs four Gs: Glück, Geduld, Geschick und Geld. Luck, patience, skill and money.
Quoted in M. Perutz, 'Rita and the Four Gs', Nature, 1988, 332, 791.
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Supposing is good, but finding out is better.
Mark Twain in Eruption: hitherto unpublished pages about men and events (1940), 324. In Caroline Thomas Harnsberger, Mark Twain at Your Fingertips (1948), 232.
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Tapestries are made by many artisans working together. The contributions of separate workers cannot be discerned in the completed work, and the loose and false threads have been covered over. So it is in our picture of particle physics.
In 'Towards a Unified Theory—Threads in a Tapestry', Nobel Lecture, 8 Dec 1979. In Nobel Lectures: Physics 1971-1980 (1992), 494. Also reproduced in Science (19 Dec 1980), New Series 210, No. 4476, 1319.
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Ten builders rear an arch, each in turn lifting it higher; but it is the tenth man, who drops in the keystone, who hears our huzzas.
From chapter 'Jottings from a Note-book', in Canadian Stories (1918), 167.
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The advancement of science is slow; it is effected only by virtue of hard work and perseverance. And when a result is attained, should we not in recognition connect it with the efforts of those who have preceded us, who have struggled and suffered in advance? Is it not truly a duty to recall the difficulties which they vanquished, the thoughts which guided them; and how men of different nations, ideas, positions, and characters, moved solely by the love of science, have bequeathed to us the unsolved problem? Should not the last comer recall the researches of his predecessors while adding in his turn his contribution of intelligence and of labor? Here is an intellectual collaboration consecrated entirely to the search for truth, and which continues from century to century.
[Respecting how the work of prior researchers had enabled his isolation of fluorine.]
Proceedings of the Royal Institution (1897). In Annual Report of the Board of Regents of the Smithsonian Institution to July 1897 (1898), 262.
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The American Cancer Society's position on the question of a possible cause-effect relationship between cigarette smoking and lung cancer is:
1. The evidence to date justifies suspicion that cigarette smoking does, to a degree as yet undetermined, increase the likelihood of developing cancer of the lung.
2. That available evidence does not constitute irrefutable proof that cigarette smoking is wholly or chiefly or partly responsible for lung cancer.
3. That the evidence at hand calls for the extension of statistical and laboratory studies designed to confirm or deny a causual relationship between cigarette smoking and lung cancer.
4. That the society is committed to furthering such intensified investigation as its resources will permit.
Conclusions of statement after a meeting of the ACS board of directors in San Francisco (17 Mar 1954). Quoted in 'Tobacco Industry Denies Cancer Tie'. New York Times (14 Apr 1954), 51.
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The art of research [is] the art of making difficult problems soluble by devising means of getting at them.
Pluto's Republic (1982), 2.
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The companies that can afford to do basic research (and can't afford not to) are ones that dominate their markets. … It's cheap insurance, since failing to do basic research guarantees that the next major advance will be oened by someone else.
Accidental Empires (1992), 79.
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The end of the eighteenth and the beginning of the nineteenth century were remarkable for the small amount of scientific movement going on in this country, especially in its more exact departments. ... Mathematics were at the last gasp, and Astronomy nearly so—I mean in those members of its frame which depend upon precise measurement and systematic calculation. The chilling torpor of routine had begun to spread itself over all those branches of Science which wanted the excitement of experimental research.
Quoted in Sophia Elizabeth De Morgan, Memoir of Augustus De Morgan (1882), 41
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The Europeans and the Americans are not throwing $10 billion down this gigantic tube for nothing. We're exploring the very forefront of physics and cosmology with the Large Hadron Collider because we want to have a window on creation, we want to recreate a tiny piece of Genesis to unlock some of the greatest secrets of the universe.
Quoted by Alexander G. Higgins (AP), in 'Particle Collider: Black Hole or Crucial Machine', The Journal Gazette (7 Aug 2009).
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The fact is the physical chemists never use their eyes and are most lamentably lacking in chemical culture. It is essential to cast out from our midst, root and branch, this physical element and return to our laboratories.
'Ionomania in Extremis', Chemistry and Industry, 1936, 14, 917.

The fact that the regions of nature actually covered by known laws are few and fragmentary is concealed by the natural tendency to crowd our experience into those particular regions and to leave the others to themselves. We seek out those parts that are known and familiar and avoid those that are unknown and unfamiliar. This is simply what is called 'Applied Science.'
Scientific Method: An Inquiry into the Character and Validy of Natural Law (1923), 201.
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The faculties developed by doing research are those most needed in diagnosis.
Transactions of the American Academy of Ophthalmology and Otolaryngology (1966) 70, 17 (1966)
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The faith of scientists in the power and truth of mathematics is so implicit that their work has gradually become less and less observation, and more and more calculation. The promiscuous collection and tabulation of data have given way to a process of assigning possible meanings, merely supposed real entities, to mathematical terms, working out the logical results, and then staging certain crucial experiments to check the hypothesis against the actual empirical results. But the facts which are accepted by virtue of these tests are not actually observed at all. With the advance of mathematical technique in physics, the tangible results of experiment have become less and less spectacular; on the other hand, their significance has grown in inverse proportion. The men in the laboratory have departed so far from the old forms of experimentation—typified by Galileo's weights and Franklin's kite—that they cannot be said to observe the actual objects of their curiosity at all; instead, they are watching index needles, revolving drums, and sensitive plates. No psychology of 'association' of sense-experiences can relate these data to the objects they signify, for in most cases the objects have never been experienced. Observation has become almost entirely indirect; and readings take the place of genuine witness.
Philosophy in a New Key; A Study in Inverse the Symbolism of Reason, Rite, and Art (1942), 19-20.
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The field of scientific abstraction encompasses independent kingdoms of ideas and of experiments and within these, rulers whose fame outlasts the centuries. But they are not the only kings in science. He also is a king who guides the spirit of his contemporaries by knowledge and creative work, by teaching and research in the field of applied science, and who conquers for science provinces which have only been raided by craftsmen.
While president of the German Chemical Society, making memorial remarks dedicated to the deceased Professor Lunge (Jan 1923). As quoted in Richard Willstätter, Arthur Stoll (ed. of the original German) and Lilli S. Hornig (trans.), From My Life: The Memoirs of Richard Willstätter (1958), 174-175.
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The first telescope opened the heavens; the first microscope opened the world of the microbes; radioisotopic methodology, as examplified by RIA [radioimmunoassay], has shown the potential for opening new vistas in science and medicine
'Radioimmunoassay: A Probe for the Fine Structure of Biologic Systems', Nobel Lecture (8 Dec 1977). In Nobel Lectures: Physiology or Medicine 1971-1980 (1992), 465.

The flight of most members of a profession to the high empyrean, where they can work peacefully on purely scientific problems, isolated from the turmoil of real life, was perhaps quite appropriate at an earlier stage of science; but in today's world it is a luxury we cannot afford.
The Scientific Imagination: Case Studies (1978), 250.

The functional validity of a working hypothesis is not a priori certain, because often it is initially based on intuition. However, logical deductions from such a hypothesis provide expectations (so-called prognoses) as to the circumstances under which certain phenomena will appear in nature. Such a postulate or working hypothesis can then be substantiated by additional observations ... The author calls such expectations and additional observations the prognosis-diagnosis method of research. Prognosis in science may be termed the prediction of the future finding of corroborative evidence of certain features or phenomena (diagnostic facts). This method of scientific research builds up and extends the relations between the subject and the object by means of a circuit of inductions and deductions.
In 'The Scientific Character of Geology', The Journal of Geology (Jul 1961), 69, No. 4, 454-5.
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The gentleman [Mr. Taber] from New York says [agricultural research] is all foolish. Yes; it was foolish when Burbank was experimenting with wild cactus. It was foolish when the Wright boys went down to Kitty Hawk and had a contraption there that they were going to fly like birds. It was foolish when Robert Fulton tried to put a boiler into a sail boat and steam it up the Hudson. It was foolish when one of my ancestors thought the world was round and discovered this country so that the gentleman from New York could become a Congressman. (Laughter.) ... Do not seek to stop progress; do not seek to put the hand of politics on these scientific men who are doing a great work. As the gentleman from Texas points out, it is not the discharge of these particular employees that is at stake, it is all the work of investigation, of research, of experimentation that has been going on for years that will be stopped and lost.
Speaking (28 Dec 1932) as a member of the 72nd Congress, early in the Great Depression, in opposition to an attempt to eliminate a small amount from the agricultural appropriation bill. As quoted in 'Mayor-Elect La Guardia on Research', Science (1933), New Series, 78, No. 2031, 511.
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The gradual advance of Geology, during the last twenty years, to the dignity of a science, has arisen from the laborious and extensive collection of facts, and from the enlightened spirit in which the inductions founded on those facts have been deduced and discussed. To those who are unacquainted with this science, or indeed to any person not deeply versed in the history of this and kindred subjects, it is impossible to convey a just impression of the nature of that evidence by which a multitude of its conclusions are supported:—evidence in many cases so irresistible, that the records of the past ages, to which it refers, are traced in language more imperishable than that of the historian of any human transactions; the relics of those beings, entombed in the strata which myriads of centuries have heaped upon their graves, giving a present evidence of their past existence, with which no human testimony can compete.
The Ninth Bridgewater Treatise (1838), 47-8.
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The Grand Duke [of Tuscany] …after observing the Medicaean plants several times with me … has now invited me to attach myself to him with the annual salary of one thousand florins, and with the title of Philosopher and Principal Mathematicial to His Highness; without the duties of office to perform, but with the most complete leisure; so that I can complete my Treatises...
From a letter to Kepler. Quoted in John Elliot Drinkwater Bethune, Life of Galileo Galilei (1832), 63.
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The greatest of all spectral classifiers, Antonia Maury had two strikes on her: the biggest one was, she was a woman. A woman had no chance at anything in astronomy except at Harvard in the 1880’s and 1890’s. And even there, things were rough. It now turns out that her director, E.C. Pickering, did not like the way she classified; she then refused to change to suit him; and after her great publication in Harvard Annals 28 (1897), she left Harvard—and in a sense, astronomy. ... I would say the most remarkable phenomenological investigation in modern astronomy is Miss Maury’s work in Harvard Annals 28. She didn’t have anything astrophysical to go on. Investigations between 1890 and 1900 were the origin of astrophysics. But these were solar, mostly. And there Miss Maury was on the periphery. I’ve seen pictures of groups, where she’d be standing away a little bit to one side of the other people, a little bit in the background. It was a very sad thing. When Hertzsprung wrote Pickering to congratulate him on Miss Maury’s work that had led to Hertzsprung’s discovery of super giants, Pickering is supposed to have replied that Miss Maury’s work was wrong — could not possibly be correct.
'Oral History Transcript: Dr. William Wilson Morgan' (8 Aug 1978) in the Niels Bohr Library & Archives.
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The History of Evolution is the real source of light in the investigation of organic bodies. It is applicable at every step, and all our ideas of the correlation of organic bodies will be swayed by our knowledge of the history of evolution. To carry the proof of it into all branches of research would be an almost endless task. (1828)
Quoted as an epigraph to Chap. 3, in Ernst Haeckel, The Evolution of Man, (1886), Vol 1, 48.
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The history of semiconductor physics is not one of grand heroic theories, but one of painstaking intelligent labor. Not strokes of genius producing lofty edifices, but great ingenuity and endless undulation of hope and despair. Not sweeping generalizations, but careful judgment of the border between perseverance and obstinacy. Thus the history of solid-state physics in general, and of semiconductors in particular, is not so much about great men and women and their glorious deeds, as about the unsung heroes of thousands of clever ideas and skillful experiments—reflection of an age of organization rather than of individuality.
'Selected Topics from the History of Semiconductor Physics and Its Applications', in Lillian Hoddeson et al. (eds.), Out of the Crystal Maze (1992), 474.
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The hybridoma technology was a by-product of basic research. Its success in practical applications is to a large extent the result of unexpected and unpredictable properties of the method. It thus represents another clear-cut example of the enormous practical impact of an investment in research which might not have been considered commercially worthwhile, or of immediate medical relevance. It resulted from esoteric speculations, for curiosity’s sake, only motivated by a desire to understand nature.
From Nobel Lecture (8 Dec 1984), collected in Tore Frängsmyr and ‎Jan Lindsten (eds.), Nobel Lectures in Physiology Or Medicine: 1981-1990 (1993), 267-268.
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The leading idea which is present in all our [geological] researches, and which accompanies every fresh observation, the sound of which to the ear of the student of Nature seems echoed from every part of her works, is—Time!—Time!—Time!
The Geology and Extinct Volcanoes of Central France (2nd ed., 1858), 208-9.
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The longing to behold this pre-established harmony [of phenomena and theoretical principles] is the source of the inexhaustible patience and perseverance with which Planck has devoted himself ... The state of mind which enables a man to do work of this kind is akin to that of the religious worshiper or the lover; the daily effort comes from no deliberate intention or program, but straight from the heart.
Address (1918) for Max Planck's 60th birthday, at Physical Society, Berlin, 'Principles of Research' in Essays in Science (1934), 4-5.
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The man of science has learned to believe in justification, not by faith, but by verification.
'On the Advisableness of Improving Natural knowledge' (1866). In Collected Essays (1893), Vol. 1, 41.
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The mathematics of cooperation of men and tools is interesting. Separated men trying their individual experiments contribute in proportion to their numbers and their work may be called mathematically additive. The effect of a single piece of apparatus given to one man is also additive only, but when a group of men are cooperating, as distinct from merely operating, their work raises with some higher power of the number than the first power. It approaches the square for two men and the cube for three. Two men cooperating with two different pieces of apparatus, say a special furnace and a pyrometer or a hydraulic press and new chemical substances, are more powerful than their arithmetical sum. These facts doubtless assist as assets of a research laboratory.
Quoted from a speech delivered at the fiftieth anniversary of granting of M.I.T's charter, in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 352.
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The modern research laboratory can be a large and complicated social organism.
How to Win the Nobel Prize: An Unexpected Life in Science (2004), xii.
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The most humble research scientist in the Department of Agriculture is at this time contributing more to this country than the most useful member of Congress.
Speaking (29 Dec 1932) as a member of the 72nd Congress, early in the Great Depression, in opposition to curtailing the agricultural appropriation. As quoted in 'Mayor-Elect La Guardia on Research', Science (1933), New Series, 78, No. 2031, 511. Also in A. Hunter Dupree, under subtitle 'Impact of the Great Depression' in Science in the Federal Government: A History of Policies and Activities to 1940, 344.
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The native hospital in Tunis was the focal point of my research. Often, when going to the hospital, I had to step over the bodies of typhus patients who were awaiting admission to the hospital and had fallen exhausted at the door. We had observed a certain phenomenon at the hospital, of which no one recognized the significance, and which drew my attention. In those days typhus patients were accommodated in the open medical wards. Before reaching the door of the wards they spread contagion. They transmitted the disease to the families that sheltered them, and doctors visiting them were also infected. The administrative staff admitting the patients, the personnel responsible for taking their clothes and linen, and the laundry staff were also contaminated. In spite of this, once admitted to the general ward the typhus patient did not contaminate any of the other patients, the nurses or the doctors. I took this observation as my guide. I asked myself what happened between the entrance to the hospital and the wards. This is what happened: the typhus patient was stripped of his clothes and linen, shaved and washed. The contagious agent was therefore something attached to his skin and clothing, something which soap and water could remove. It could only be the louse. It was the louse.
'Investigations on Typhus', Nobel lecture, 1928. In Nobel Lectures: Physiology or Medicine 1922-1941 (1965), 181.
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The object of geometry in all its measuring and computing, is to ascertain with exactness the plan of the great Geometer, to penetrate the veil of material forms, and disclose the thoughts which lie beneath them? When our researches are successful, and when a generous and heaven-eyed inspiration has elevated us above humanity, and raised us triumphantly into the very presence, as it were, of the divine intellect, how instantly and entirely are human pride and vanity repressed, and, by a single glance at the glories of the infinite mind, are we humbled to the dust.
From 'Mathematical Investigation of the Fractions Which Occur in Phyllotaxis', Proceedings of the American Association for the Advancement of Science (1850), 2, 447, as quoted by R. C. Archibald in 'Benjamin Peirce: V. Biographical Sketch', The American Mathematical Monthly (Jan 1925), 32, No. 1, 12.
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The outcome of any serious research can only be to make two questions grow where only one grew before.
'Evolution of the Scientific Point of View', essay, collected in The Place of Science in Modern Civilisation and Other Essays (1919), 33.
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The phosphorous smell which is developed when electricity (to speak the profane language) is passing from the points of a conductor into air, or when lightning happens to fall upon some terrestrial object, or when water is electrolysed, has been engaging my attention the last couple of years, and induced me to make many attempts at clearing up that mysterious phenomenon. Though baffled for a long time, at last, I think, I have succeeded so far as to have got the clue which will lead to the discovery of the true cause of the smell in question.
[His first reference to investigating ozone, for which he is remembered.]
Letter to Michael Faraday (4 Apr 1840), The Letters of Faraday and Schoenbein, 1836-1862 (1899), 73. This letter was communicated to the Royal Society on 7 May, and an abstract published in the Philosophical Magazine.
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The problem [with genetic research] is, we're just starting down this path, feeling our way in the dark. We have a small lantern in the form of a gene, but the lantern doesn't penetrate more than a couple of hundred feet. We don't know whether we're going to encounter chasms, rock walls or mountain ranges along the way. We don't even know how long the path is.
Quoted in J. Madeleine Nash, et al., 'Tracking Down Killer Genes', Time magazine (17 Sep 1990).
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The pure culture is the foundation for all research on infectious disease.
'Zur Untersuchungen von Pathologen Organismen', Mittheilungen aus dem Kaiserlichen Gesundheitsamte (1881), 1, 1-48. Quoted in English in Thomas D. Brock, Robert Koch: A Life in Medicine and Bacteriology (1988), 94.
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The Reason of making Experiments is, for the Discovery of the Method of Nature, in its Progress and Operations. Whosoever, therefore doth rightly make Experiments, doth design to enquire into some of these Operations; and, in order thereunto, doth consider what Circumstances and Effects, in the Experiment, will be material and instructive in that Enquiry, whether for the confirming or destroying of any preconceived Notion, or for the Limitation and Bounding thereof, either to this or that Part of the Hypothesis, by allowing a greater Latitude and Extent to one Part, and by diminishing or restraining another Part within narrower Bounds than were at first imagin'd, or hypothetically supposed. The Method therefore of making Experiments by the Royal Society I conceive should be this.
First, To propound the Design and Aim of the Curator in his present Enquiry.
Secondly, To make the Experiment, or Experiments, leisurely, and with Care and Exactness.
Thirdly, To be diligent, accurate, and curious, in taking Notice of, and shewing to the Assembly of Spectators, such Circumstances and Effects therein occurring, as are material, or at least, as he conceives such, in order to his Theory .
Fourthly, After finishing the Experiment, to discourse, argue, defend, and further explain, such Circumstances and Effects in the preceding Experiments, as may seem dubious or difficult: And to propound what new Difficulties and Queries do occur, that require other Trials and Experiments to be made, in order to their clearing and answering: And farther, to raise such Axioms and Propositions, as are thereby plainly demonstrated and proved.
Fifthly, To register the whole Process of the Proposal, Design, Experiment, Success, or Failure; the Objections and Objectors, the Explanation and Explainers, the Proposals and Propounders of new and farther Trials; the Theories and Axioms, and their Authors; and, in a Word the history of every Thing and Person, that is material and circumstantial in the whole Entertainment of the said Society; which shall be prepared and made ready, fairly written in a bound Book, to be read at the Beginning of the Sitting of the Society: The next Day of their Meeting, then to be read over and further discoursed, augmented or diminished, as the Matter shall require, and then to be sign'd by a certain Number of the Persons present, who have been present, and Witnesses of all the said Proceedings, who, by Subscribing their names, will prove undoubted testimony to Posterity of the whole History.
'Dr Hooke's Method of Making Experiments' (1664-5). In W. Derham (ed.), Philosophical Experiments and Observations Of the Late Eminent Dr. Robert Hooke, F.R.S. And Geom. Prof. Gresh. and Other Eminent Virtuoso's in his Time (1726), 26-8.
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The religious right around the world has made embryonic stem cell research the surrogate battle between religion and science.
In Eve Herold, George Daley, Stem Cell Wars (2007), 21.
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The research worker, in his efforts to express the fundamental laws of Nature in mathematical form, should strive mainly for mathematical beauty. He should take simplicity into consideration in a subordinate way to beauty ... It often happens that the requirements of simplicity and beauty are the same, but where they clash, the latter must take precedence.
"Proceedings of the Royal Society of Edinburgh (1939), 59 122. In A. Pais, 'Playing With Equations, the Dirac Way'. Behram N. Kursunoglu (Ed.) and Eugene Paul Wigner (Ed.), Paul Adrien Maurice Dirac: Reminiscences about a Great Physicist (1990), 110.
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The resolution of revolutions is selection by conflict within the scientific community of the fittest way to practice future science. The net result of a sequence of such revolutionary selections, separated by periods of normal research, is the wonderfully adapted set of instruments we call modern scientific knowledge.
The Structure of Scientific Revolutions (1962), 171.
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The role of hypothesis in research can be discussed more effectively if we consider first some examples of discoveries which originated from hypotheses. One of the best illustrations of such a discovery is provided by the story of Christopher Columbus' voyage; it has many of the features of a classic discovery in science. (a) He was obsessed with an idea—that since the world is round he could reach the Orient by sailing West, (b) the idea was by no means original, but evidently he had obtained some additional evidence from a sailor blown off his course who claimed to have reached land in the west and returned, (c) he met great difficulties in getting someone to provide the money to enable him to test his idea as well as in the actual carrying out of the experimental voyage, (d) when finally he succeeded he did not find the expected new route, but instead found a whole new world, (e) despite all evidence to the contrary he clung to the bitter end to his hypothesis and believed that he had found the route to the Orient, (f) he got little credit or reward during his lifetime and neither he nor others realised the full implications of his discovery, (g) since his time evidence has been brought forward showing that he was by no means the first European to reach America.
The Art of Scientific Investigation (1950), 41.
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The science and technology which have advanced man safely into space have brought about startling medical advances for man on earth. Out of space research have come new knowledge, techniques and instruments which have enabled some bedridden invalids to walk, the totally deaf to hear, the voiceless to talk, and, in the foreseeable future, may even make it possible for the blind to "see."
'From Outer Space—Advances For Medicine on Earth', contributed in Lillian Levy, Space, Its Impact on Man and Society (1965, reprinted 1973), 117.
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The science of genetics is in a transition period, becoming an exact science just as the chemistry in the times of Lavoisier, who made the balance an indispensable implement in chemical research.
The Genotype Conception of Heredity', The American Naturalist (1911), 45, 131.
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The sciences are found, like Hercules's oxen, by tracing them backward; and old sciences are unravelled like old stockings, by beginning at the foot.
The Works of the Rev. Jonathan Swift (1803), 388.
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The scientific enterprise is full of experts on specialist areas but woefully short of people with a unified worldview. This state of affairs can only inhibit progress, and could threaten political and financial support for research.
Commentary, Nature (14 Aug 1997), 619. Quoted in Denis Alexander, Rebuilding the Matrix (2003), 7.
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The scientific man does not aim at an immediate result. He does not expect that his advanced ideas will be readily taken up. His work is like that of the planter—for the future. His duty is to lay the foundation for those who are to come, and point the way.
'The Problem of Increasing Human Energy', The Century (Jun 1900), 211. Collected in The Century (1900), Vol. 60, 211
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The self-regulating mechanism of the market place cannot always be depended upon to produce adequate results in scientific research.
[Co-author with American lawyer Byron S. Miller (1915-2003)]
The Control of Atomic Energy (1948), 17
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The simplest way to assure sales is to keep changing the product the market for new things is indefinitely elastic. One of the fundamental purposes of advertising, styling, and research is to foster a healthy dissatisfaction.
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The situation with regard to insulin is particularly clear. In many parts of the world diabetic children still die from lack of this hormone. ... [T]hose of us who search for new biological facts and for new and better therapeutic weapons should appreciate that one of the central problems of the world is the more equitable distribution and use of the medical and nutritional advances which have already been established. The observations which I have recently made in parts of Africa and South America have brought this fact very forcible to my attention.
'Studies on Diabetes and Cirrhosis', Proceedings, American Philosophical Society (1952) 96, No. 1, 29.
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The skeptic does not mean him who doubts, but him who investigates or researches, as opposed to him who asserts and thinks that he has found. The one is the man who studies the problem and the other is the man who gives us a formula, correct or incorrect, as the solution of it.
'My Religion', Essays and Soliloquies, translated by John Ernest Crawford Flitch (1925), 56. In Robert Andrews, The Columbia Dictionary of Quotations (1993), 844:9.
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The steam-engine in its manifold applications, the crime-decreasing gas-lamp, the lightning conductor, the electric telegraph, the law of storms and rules for the mariner's guidance in them, the power of rendering surgical operations painless, the measures for preserving public health, and for preventing or mitigating epidemics,—such are among the more important practical results of pure scientific research, with which mankind have been blessed and States enriched.
President's Address to the British Association, Leeds (1858). In Charles W. Vincent and James Mason (eds.), The Year-book of Facts in Science and Art (1859), title page.
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The strength of all sciences is, as the strength of the old man's faggot, in the bond. For the harmony of a science, supporting each part the other, is and ought to be the true and brief confutation and suppression of all the smaller sort of objections; but, on the other side, if you take out every axiom, as the sticks of the faggot, one by one, you may quarrel with them and bend them and break them at your pleasure: so that, as was said of Seneca, Verborum minutiis rerum frangit pondera [that he broke up the weight and mass of the matter by verbal points and niceties], so a man may truly say of the schoolmen, Quaestionum minutiis scientiarum frangunt soliditatem [they broke up the solidarity and coherency of the sciences by the minuteness and nicety of their questions]. For were it not better for a man in fair room to set up one great light, or branching candlestick of lights, than to go about with a small watch-candle into every corner?
The Works of Francis Bacon (1864), Vol. 6, 123
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The techniques have galloped ahead of the concepts. We have moved away from studying the complexity of the organism; from processes and organisation to composition.
[Commenting that growing use of new technologies and techniques, from molecular biology to genomics, has proved a mixed blessing.]
Quoted in Andrew Jack, "An Acute Talent for Innovation", Financial Times (1 Feb 2009).
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The time will come when diligent research over long periods will bring to light things which now lie hidden. A single lifetime, even though entirely devoted to the sky, would not be enough for the investigation of so vast a subject ... And so this knowledge will be unfolded only through long successive ages. There will come a time when our descendants will be amazed that we did not know things that are so plain to them ... Many discoveries are reserved for ages still to come, when memory of us will have been effaced. Our universe is a sorry little affair unless it has in it something for every age to investigate ... Nature does not reveal her mysteries once and for all.
Natural Questions, Book 7. As translated by Thomas H. Corcoran in Seneca in Ten Volumes: Naturales Quaestiones II (1972), 279 and 293.
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The whole strenuous intellectual work of an industrious research worker would appear, after all, in vain and hopeless, if he were not occasionally through some striking facts to find that he had, at the end of all his criss-cross journeys, at last accomplished at least one step which was conclusively nearer the truth.
Nobel Lecture (2 Jun 1920), in Nobel Lectures in Physics, 1901-1921 (1998), 407.
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The woof and warp of all thought and all research is symbols, and the life of thought and science is the life inherent in symbols; so that it is wrong to say that a good language is important to good thought, merely; for it is the essence of it.
From 'The Ethics of Terminology', in Collected Papers (1931), Vol. 1, 129.
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The world is so full of a number of things
I'm sure we should all be as happy as kings.
'Happy Thought', The Works of Robert Louis Stevenson (1896), 540.

The world was full of locked doors, and he had to get his hand on every key.
Ender's Shadow (1999)
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There are no enemies in science, professor, only phenomena to study.
Movie, The Thing (from Another World) (1951). In Gary Westfahl, Science Fiction Quotations: From the Inner Mind to the Outer Limits (2006), 320.
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There are still many unsolved problems about bird life, among which are the age that birds attain, the exact time at which some birds acquire their adult dress, and the changes which occur in this with years. Little, too, is known about the laws and routes of bird migration, and much less about the final disposition of the untold thousands which are annually produced.
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There are those who say we cannot afford to invest in science, that support for research is somehow a luxury at moments defined by necessities. I fundamentally disagree. Science is more essential for our prosperity, our security, our health, our environment, and our quality of life than it has ever been before. … we can't allow our nation to fall behind. Unfortunately, that's exactly what's happened. Federal funding in the physical sciences as a portion of our gross domestic product has fallen by nearly half over the past quarter century. Time and again we've allowed the research and experimentation tax credit, which helps businesses grow and innovate, to lapse.
Speech to the National Academy of Sciences Annual Meeting (27 Apr 2009).
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There is in the chemist a form of thought by which all ideas become visible in the mind as strains of an imagined piece of music. This form of thought is developed in Faraday in the highest degree, whence it arises that to one who is not acquainted with this method of thinking, his scientific works seem barren and dry, and merely a series of researches strung together, while his oral discourse when he teaches or explains is intellectual, elegant, and of wonderful clearness.
Autobiography, 257-358. Quoted in William H. Brock, Justus Von Liebig (2002), 9.
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There is, however, no universal recipe for scientific advance. It is a matter of groping forward into terra incognita of the outer world by means of methods which should be adapted to the circumstances.
In 'The Scientific Character of Geology', The Journal of Geology (Jul 1961), 69, No. 4, 455.
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There seems no limit to research, for as been truly said, the more the sphere of knowledge grows, the larger becomes the surface of contact with the unknown.
from A History of Science and Its Relations with Philosophy and Religion, 4th Ed., Cambridge University Press, 1961, p. 500.
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These parsons are so in the habit of dealing with the abstractions of doctrines as if there was no difficulty about them whatever, so confident, from the practice of having the talk all to themselves for an hour at least every week with no one to gainsay a syllable they utter, be it ever so loose or bad, that they gallop over the course when their field is Botany or Geology as if we were in the pews and they in the pulpit ... There is a story somewhere of an Englishman, Frenchman, and German being each called on to describe a camel. The Englishman immediately embarked for Egypt, the Frenchman went to the Jardin des Plantes, and the German shut himself up in his study and thought it out!
Letter to Asa Gray (29 Mar 1857). Quoted in Leonard Huxley, Life and Letters of Sir Joseph Dalton Hooker (1918), Vol. 1, 477.
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Think of a single problem confronting the world today. Disease, poverty, global warming… If the problem is going to be solved, it is science that is going to solve it. Scientists tend to be unappreciated in the world at large, but you can hardly overstate the importance of the work they do. If anyone ever cures cancer, it will be a guy with a science degree. Or a woman with a science degree.
Quoted in Max Davidson, 'Bill Bryson: Have faith, science can solve our problems', Daily Telegraph (26 Sep 2010)
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This characteristic of modern experiments–that they consist principally of measurements,–is so prominent, that the opinion seems to have got abroad, that in a few years all the great physical constants will have been approximately estimated, and that the only occupation which will then be left to men of science will be to carry these measurements to another place of decimals ... But we have no right to think thus of the unsearchable riches of creation, or of the untried fertility of those fresh minds into which these riches will continue to be poured.
[Maxwell strongly disagreed with the prominent opinion, and was attacking it. Thus, he was saying he did not believe in such a future of merely making 'measurements to another place of decimals.']
'Introductory Lecture on Experimental Physics', Oct 1871. In W. D. Niven (ed.), Scientific Papers (1890), Vol. 2, 244. Note that his reference to making measurements to another place of decimals is often seen extracted as a short quote without the context showing he actually despised that opinion.
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This example illustrates the differences in the effects which may be produced by research in pure or applied science. A research on the lines of applied science would doubtless have led to improvement and development of the older methods—the research in pure science has given us an entirely new and much more powerful method. In fact, research in applied science leads to reforms, research in pure science leads to revolutions, and revolutions, whether political or industrial, are exceedingly profitable things if you are on the winning side.
In Lord Rayleigh, The Life of Sir J. J. Thomson (1943), 199
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This is the element that distinguishes applied science from basic. Surprise is what makes the difference. When you are organized to apply knowledge, set up targets, produce a usable product, you require a high degree of certainty from the outset. All the facts on which you base protocols must be reasonably hard facts with unambiguous meaning. The challenge is to plan the work and organize the workers so that it will come out precisely as predicted. For this, you need centralized authority, elaborately detailed time schedules, and some sort of reward system based on speed and perfection. But most of all you need the intelligible basic facts to begin with, and these must come from basic research. There is no other source. In basic research, everything is just the opposite. What you need at the outset is a high degree of uncertainty; otherwise it isn't likely to be an important problem. You start with an incomplete roster of facts, characterized by their ambiguity; often the problem consists of discovering the connections between unrelated pieces of information. You must plan experiments on the basis of probability, even bare possibility, rather than certainty.
The Planning of Science, The Lives of a Cell: Notes of a Biology Watcher, (1974) .
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This means that we have here an entirely separate kind of chemistry for which the current tool we use is the electrometer, not the balance, and which we might well call the chemistry of the imponderable.
(11 Dec 1911) As quoted in Marie and Pierre Curie and the Discovery of Polonium and Radium, Nobel Lecture
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This was what the universities were turning out nowadays. The science-is-a-sacred-cow boys. People who believe you could pour mankind into a test-tube and titrate it, and come up with all the answers to the problems of the human race.
The Day the World Ended (1953). Quoted in Gary Westfahl, Science Fiction Quotations (2005), 320-321.
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Those of us who were familiar with the state of inorganic chemistry in universities twenty to thirty years ago will recall that at that time it was widely regarded as a dull and uninteresting part of the undergraduate course. Usually, it was taught almost entirely in the early years of the course and then chiefly as a collection of largely unconnected facts. On the whole, students concluded that, apart from some relationships dependent upon the Periodic table, there was no system in inorganic chemistry comparable with that to be found in organic chemistry, and none of the rigour and logic which characterised physical chemistry. It was widely believed that the opportunities for research in inorganic chemistry were few, and that in any case the problems were dull and uninspiring; as a result, relatively few people specialized in the subject... So long as inorganic chemistry is regarded as, in years gone by, as consisting simply of the preparations and analysis of elements and compounds, its lack of appeal is only to be expected. The stage is now past and for the purpose of our discussion we shall define inorganic chemistry today as the integrated study of the formation, composition, structure and reactions of the chemical elements and compounds, excepting most of those of carbon.
Inaugural Lecture delivered at University College, London (1 Mar 1956). In The Renaissance of Inorganic Chemistry (1956), 4-5.
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Those who are unacquainted with the details of scientific investigation have no idea of the amount of labour expended in the determination of those numbers on which important calculations or inferences depend. They have no idea of the patience shown by a Berzelius in determining atomic weights; by a Regnault in determining coefficients of expansion; or by a Joule in determining the mechanical equivalent of heat.
In Sound: A Course of Eight Lectures Delivered at the Royal Institution of Great Britain (1867), 26.
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Those who have handled sciences have been either men of experiment or men of dogmas. The men of experiment are like the ant; they only collect and use; the reasoners resemble spiders, who make cobwebs out of their own substance. But the bee takes a middle course; it gathers its material from the flowers of the garden and of the field, but transforms and digests it by a power of its own. Not unlike this is the true business of philosophy; for it neither relies solely or chiefly on the powers of the mind, nor does it take the matter which it gathers from natural history and mechanical experiments and lay it up in the memory whole, as it finds it; but lays it up in the understanding altered and digested. Therefore from a closer and purer league between these two faculties, the experimental and the rational (such as has never yet been made), much may be hoped.
The New Organon (1620) in James Spedding, Robert Ellis and Douglas Heath (eds.), The Works of Francis Bacon (1887-1901), Vol. 4, 92-3.
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Tis Man's to explore up and down, inch by inch, with the taper his reason.
'Apollo and the Fates', The Complete Poetic and Dramatic Works of Robert Browning (1895), 951.
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To find out what happens to a system when you interfere with it you have to interfere with it (not just passively observe it).
Use and Abuse of Regression (1966), 629.
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To prove to an indignant questioner on the spur of the moment that the work I do was useful seemed a thankless task and I gave it up. I turned to him with a smile and finished, 'To tell you the truth we don't do it because it is useful but because it's amusing.' The answer was thought of and given in a moment: it came from deep down in my soul, and the results were as admirable from my point of view as unexpected. My audience was clearly on my side. Prolonged and hearty applause greeted my confession. My questioner retired shaking his head over my wickedness and the newspapers next day, with obvious approval, came out with headlines 'Scientist Does It Because It's Amusing!' And if that is not the best reason why a scientist should do his work, I want to know what is. Would it be any good to ask a mother what practical use her baby is? That, as I say, was the first evening I ever spent in the United States and from that moment I felt at home. I realised that all talk about science purely for its practical and wealth-producing results is as idle in this country as in England. Practical results will follow right enough. No real knowledge is sterile. The most useless investigation may prove to have the most startling practical importance: Wireless telegraphy might not yet have come if Clerk Maxwell had been drawn away from his obviously 'useless' equations to do something of more practical importance. Large branches of chemistry would have remained obscure had Willard Gibbs not spent his time at mathematical calculations which only about two men of his generation could understand. With this faith in the ultimate usefulness of all real knowledge a man may proceed to devote himself to a study of first causes without apology, and without hope of immediate return.
A.V. Hill
Quoted in Larry R. Squire (ed.), The History of Neuroscience in Autobiography (1996), Vol. I, 351.
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To stop short in any research that bids fair to widen the gates of knowledge, to recoil from fear of difficulty or adverse criticism, is to bring reproach on science. There is nothing for the investigator to do but go straight on, 'to explore up and down, inch by inch, with the taper his reason;' to follow the light wherever it may lead, even should it at times resemble a will-o'-the-wisp.
Referring to his interest in psychical (spiritual) research.
Presidential address to the British Association (1898). Quoted in Harold Begbie in Pall Mall magazine (Jan 1903). In Albert Shaw, The American Monthly Review of Reviews (1903), 27, 232.
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To this I may add another form of temptation, manifold in its dangers ... There exists in the soul ... a cupidity which does not take delight in the carnal pleasure but in perceptions acquired through the flesh. It is a vain inquisitiveness dignified with the title of knowledge and science. As this is rooted in the appetite for knowing, and as among the senses the eyes play a leading role in acquiring knowledge, the divine word calls it 'the lust of the eyes' (I John, 2: 16) ... To satisfy this diseased craving ... people study the operations of nature, which lie beyond our grasp when there is no advantage in knowing and the investigators simply desire knowledge for its own sake. This motive is again at work if, using a perverted science for the same end, people try to achieve things by magical arts.
Confessions [c.397], Book X, chapter 35 (54-55), trans. H. Chadwick (1991), 210-212.
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To-day, science has withdrawn into realms that are hardly understanded of the people. Biology means very largely histology, the study of the cell by difficult and elaborate microscopical processes. Chemistry has passed from the mixing of simple substances with ascertained reactions, to an experimentation of these processes under varying conditions of temperature, pressure, and electrification—all requiring complicated apparatus and the most delicate measurement and manipulation. Similarly, physics has outgrown the old formulas of gravity, magnetism, and pressure; has discarded the molecule and atom for the ion, and may in its recent generalizations be followed only by an expert in the higher, not to say the transcendental mathematics.
Anonymous
‘Exit the Amateur Scientist.’ Editorial, The Nation, 23 August 1906, 83, 160.
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Train yourselves. Don't wait to be fed knowledge out of a book. Get out and seek it. Make explorations. Do your own research work. Train your hands and your mind. Become curious. Invent your own problems and solve them. You can see things going on all about you. Inquire into them. Seek out answers to your own questions. There are many phenomena going on in nature the explanation of which cannot be found in books. Find out why these phenomena take place. Information a boy gets by himself is enormously more valuable than that which is taught to him in school.
In 'Dr. Irving Langmuir', Boys' Life (Jul 1941), 12.
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True optimization is the revolutionary contribution of modern research to decision processes.
In Eberhard Zeidler, Applied Functional Analysis: main principles and their applications (1995), 1.
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Truth is compared in Scripture to a streaming fountain; if her waters flow not in perpetual progression, they sicken into a muddy pool of conformity and tradition.
The Homiletic Review, Vol. 83-84 (1922), Vol. 83, 208.
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Unless there exist peculiar institutions for the support of such inquirers, or unless the Government directly interfere, the contriver of a thaumatrope may derive profit from his ingenuity, whilst he who unravels the laws of light and vision, on which multitudes of phenomena depend, shall descend unrewarded to the tomb.
Reflections on the Decline of Science in England (1830), 19.
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We cannot step aside and say that we have achieved our goal by inventing a new drug or a new way by which to treat presently incurable diseases, a new way to help those who suffer from malnutrition, or the creation of ideal balanced diets on a worldwide scale. We cannot rest till the way has been found, with our help, to bring our finest achievement to everyone.
Address to the Medical College of Virginia, Richmond (1 Dec 1950).
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We do not live in a time when knowledge can be extended along a pathway smooth and free from obstacles, as at the time of the discovery of the infinitesimal calculus, and in a measure also when in the development of projective geometry obstacles were suddenly removed which, having hemmed progress for a long time, permitted a stream of investigators to pour in upon virgin soil. There is no longer any browsing along the beaten paths; and into the primeval forest only those may venture who are equipped with the sharpest tools.
'Mathematisches und wissenschaftliches Denken', Jahresbericht der Deutschen Mathematiker Vereinigung, Bd. 11, 55. In Robert Édouard Moritz, Memorabilia Mathematica; Or, The Philomath's Quotation-book (1914), 91.
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We have a habit in writing articles published in scientific journals to make the work as finished as possible, to cover up all the tracks, to not worry about the blind alleys or describe how you had the wrong idea first, and so on. So there isn't any place to publish, in a dignified manner, what you actually did in order to get to do the work, although, there has been in these days, some interest in this kind, thing.
'The Development of Space-time View of Quantum Electrodynamics', Nobel Lecture, 11 Dec 1965. In Nobel Lectures: Physics 1963-1970 (1972), 155.
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We have been forced to admit for the first time in history not only the possibility of the fact of the growth and decay of the elements of matter. With radium and with uranium we do not see anything but the decay. And yet, somewhere, somehow, it is almost certain that these elements must be continuously forming. They are probably being put together now in the laboratory of the stars. ... Can we ever learn to control the process. Why not? Only research can tell.
'The Significance of Radium,' an address delivered (in connection with the presentation of a gram of radium to Madame Curie) at the National Museum, Washington, D.C. (25 May 1921). In Science (1921), 54, No. 1383, 1921. In Rodney P. Carlisle, Scientific American Inventions and Discoveries (2004), 375.
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We have to keep in practice like musicians. Besides, there are still potentialities to be realized in color film. To us, it's just like bringing up a child. You don't stop after you've had it.
[On product improvement research.]
Quoted in Alix Kerr, 'What It Took: Intuition, Goo,' Life (25 Jan 1963), 54, No. 4, 86.
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We must not forget that when radium was discovered no one knew that it would prove useful in hospitals. The work was one of pure science. And this is a proof that scientific work must not be considered from the point of view of the direct usefulness of it. It must be done for itself, for the beauty of science, and then there is always the chance that a scientific discovery may become like the radium a benefit for humanity.
Lecture at Vassar College, Poughkeepsie, New York (14 May 1921). In Cambridge Editorial Partnership, Speeches that Changed the World, 53.
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We must painfully acknowledge that, precisely because of its great intellectual developments, the best of man's domesticated animals—the dog—most often becomes the victim of physiological experiments. Only dire necessity can lead one to experiment on cats—on such impatient, loud, malicious animals. During chronic experiments, when the animal, having recovered from its operation, is under lengthy observation, the dog is irreplaceable; moreover, it is extremely touching. It is almost a participant in the experiments conducted upon it, greatly facilitating the success of the research by its understanding and compliance.
'Vivisection' (1893), as translated in Daniel P. Todes, Pavlov's Physiology Factory: Experiment, Interpretation, Laboratory Enterprise (2002), 123.
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We must remain, in a word, in an intellectual disposition which seems paradoxical, but which, in my opinion, represents the true mind of the investigator. We must have a robust faith and yet not believe.
[Often seen summarized as: The investigator should have a robust faith—and yet not believe.]
Introduction to the Study of Experimental Medicine (1865). In Alan S. Weber, Nineteenth Century Science: a Selection of Original Texts (2000), 333.
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We should misjudge this scientist [Fritz Haber] seriously if we were to judge him only by his harvest. The stimulation of research and the advancement of younger scholars become ever more important to him than his own achievements.
In Richard Willstätter, Arthur Stoll (ed. of the original German) and Lilli S. Hornig (trans.), From My Life: The Memoirs of Richard Willstätter (1958), 269.
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We spend long hours discussing the curious situation that the two great bodies of biological knowledge, genetics and embryology, which were obviously intimately interrelated in development, had never been brought together in any revealing way. An obvious difficulty was that the most favorable organisms for genetics, Drosophila as a prime example, were not well suited for embryological study, and the classical objects of embryological study, sea urchins and frogs as examples, were not easily investigated genetically. What might we do about it? There were two obvious approaches: one to learn more about the genetics of an embryologically favourable organism, the other to better understand the development of Drosophila. We resolved to gamble up to a year of our lives on the latter approach, this in Ephrussi's laboratory in Paris which was admirably equipped for tissue culture, tissue or organ transplantation, and related techniques.
'Recollections', Annual Review of Biochemistry, 1974, 43, 6.
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We took on things which people might think would take a year or two. They weren't particularly hard. What was hard was believing they weren't hard.
[Recalling high-pressure, short-deadline problem solving leading up to planned release date of Polaroid instant color film.]
Quoted in Alix Kerr, 'What It Took: Intuition, Goo,' Life (25 Jan 1963), 54, No. 4, 86.
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What a delight it is to think that you are quietly & philosophically at work in the pursuit of science... rather than fighting amongst the crowd of black passions & motives that seem now a days to urge men every where into action. What incredible scenes every where, what unworthy motives ruled for the moment, under high sounding phrases and at the last what disgusting revolutions.
Letter to C. Schrenbein, 15 Dec 1848. In Frank A. J. L. James (ed.), The Correspondence of Michael Faraday (1996), Vol. 3, 742.

What are they doing, examining last month's costs with a microscope when they should be surveying the horizon with a telescope?
[Acerbic comment about directors of Brunner Mond, where he worked.]
As quoted by Peter Allen in obituary, Biographical Memoirs of Fellows of the Royal Society (Nov 1976), 22, 116.
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What I really want is a creative person. You can always hire a Ph.D. to take care of the details.
A recollection by Ray Hunder on Drew's philosophy, as quoted in A Century of Innovation: The 3M Story (2002), 27. (Note: The quote is in the words of Ray Hunder, and not necessarily a verbatim quote as spoken by Drew.)
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What is research, but a blind date with knowledge.
Anonymous
Quoted in Robert S. Ely, Creating the Creative (2006), 60, attributed to William Henry, but without citation. It is seen in different sources variously attributed to William Henry, William J. Henry, Will Henry or Will Harvey. Webmaster has not found a primary print source documenting its authenticity. If you can supply one, please contact the webmaster. Meanwhile, it is listed here as anonymous.
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When I arrived in California to join the faculty of the New University which opened in October 1891, it was near the end of the dry season and probably no rain had fallen for three or four months. The bare cracked adobe fields surrounding the new buildings ... offered a decidedly unpromising outlook... A month or two later, however, there was a magical transformation. With the advent of the autumn rains the whole country quickly turned green, and a profusion of liverworts such as I had never seen before appeared on the open ground... I soon realized that right in my own backyard, so to speak, was a wealth of material such as I had never imagined would be my good fortune to encounter. ... Such an invitation to make a comprehensive study of the structure and development of the liverworts could not be resisted; and the next three years were largely devoted to this work which finally resulted in the publication of 'The Mosses and Ferns' in 1895.
In The Structure and Development of Mosses and Ferns (Archegoniatae) (1905, 3rd ed. 1918, rev. 1928). Cited in William C. Steere, Obituary, 'Douglas Houghton Campbell', American Bryological and Lichenological Society, The Bryologist (1953), 131.
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When they [radio astronomers] grew weary at their electronic listening posts. When their eyes grew dim with looking at unrevealing dials and studying uneventful graphs, they could step outside their concrete cells and renew their dull spirits in communion with the giant mechanism they commanded, the silent, sensing instrument in which the smallest packets of energy, the smallest waves of matter, were detected in their headlong, eternal flight across the universe. It was the stethoscope with which they took the pulse of the all and noted the birth and death of stars, the probe which, here on an insignificant planet of an undistinguishable star on the edge of its galaxy, they explored the infinite.
The Listeners (1968, 1972), 12.
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Wherever it was, I did not come to know it through the bodily senses; the only things we know through the bodily senses are material objects, which we have found are not truly and simply one. Moreover, if we do not perceive one by the bodily sense, then we do not perceive any number by that sense, at least of those numbers that we grasp by understanding.
De Ubero Arbitrio (On Free Choice of the Will) [386], trans. T. Williams (1993), 45.
Science quotes on:  |  Mathematics (355)

Will fluorine ever have practical applications?
It is very difficult to answer this question. I may, however, say in all sincerity that I gave this subject little thought when I undertook my researches, and I believe that all the chemists whose attempts preceded mine gave it no more consideration.
A scientific research is a search after truth, and it is only after discovery that the question of applicability can be usefully considered.
Proceedings of the Royal Institution (1897). In Annual Report of the Board of Regents of the Smithsonian Institution to July 1897 (1898), 261.
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Willis Rodney Whitney ... once compared scientific research to a bridge being constructed by a builder who was fascinated by the construction problems involved. Basic research, he suggested, is such a bridge built wherever it strikes the builder's fancy—wherever the construction problems seem to him to be most challenging. Applied research, on the other hand, is a bridge built where people are waiting to get across the river. The challenge to the builder's ingenuity and skill, Whitney pointed out, can be as great in one case as the other.
'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 351.
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With the ministry’s motto ‘Research on a Shoestring’ emblazoned on his coat of arms, he has to struggle with a treasury more interested in surtax relief than national survival. [Responding to an earlier statement by British Science Minister, Lord Hailsham, that British scientists were being recruited by the U.S.]
Address at the Imperial College of Science and Technology, London (28 Feb 1963). In 'Hailsham Chided on Science's Role', New York Times (1 Mar 1963), 2. See also aron Hailsham's original statement using the link below.
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Yes indeed: the human mind, so blind and languid, shamefully and dishonourably wishes to hide, and yet does not wish anything to be concealed from itself. But it is repaid on the principle that while the human mind lies open to the truth, truth remains hidden from it. Yet even thus, in its miserable condition, it prefers to find joy in true rather than false things. It will be happy if it comes to find joy only in that truth by which all things are true—without any distraction interfering.
Confessions [c.397], Book X, chapter 23 (34), trans. H. Chadwick (1991), 200.
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Yet, in holding scientific research and discovery in respect, as we should, we must also be alert to the equal and opposite danger that public policy could itself become the captive of a scientific-technological elite.
Farewell Address as U.S. President (1961). In Diane Ravitch, The American Reader (2000), 538.
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You must never believe all these things which the scientists say because they always want more than they can get—they are never satisfied.
[Responding to a complaint of inadequate support for research.]
Quoted in Senate Internal Security Subcommittee, Nuclear Scientist Defect to the United States (1965). In Daniel S. Greenberg, The Politics of Pure Science (1999), 156, footnote.
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You've to go out on a limb sometimes, because that's where the fruit is.
In Juanita Rose Violini, Almanac of the Infamous, the Incredible, and the Ignored (2009), 56. If you know a primary source, please contact Webmaster, who has not yet found a primary source for this quote, although seen widely attributed to Will Rogers.
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[Before the time of Benjamin Peirce it never occurred to anyone that mathematical research] was one of the things for which a mathematical department existed. Today it is a commonplace in all the leading universities. Peirce stood alone—a mountain peak whose absolute height might be hard to measure, but which towered above all the surrounding country.
In 'The Story of Mathematics at Harvard', Harvard Alumni Bulletin (3 Jan 1924), 26, 376. Cited by R. C. Archibald in 'Benjamin Peirce: V. Biographical Sketch', The American Mathematical Monthly (Jan 1925), 32, No. 1, 10.
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[For] men to whom nothing seems great but reason ... nature ... is a cosmos, so admirable, that to penetrate to its ways seems to them the only thing that makes life worth living. These are the men whom we see possessed by a passion to learn ... Those are the natural scientific men; and they are the only men that have any real success in scientific research.
From 'Lessons from the History of Science: The Scientific Attitude' (c.1896), in Collected Papers (1931), Vol. 1, 19.
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[In research on bacteria metabolism] we have indeed much the same position as an observer trying to gain an idea of the life of a household by careful scrutiny of the persons and material arriving or leaving the house; we keep accurate records of the foods and commodities left at the door and patiently examine the contents of the dust-bin and endeavour to deduce from such data the events occurring within the closed doors.
Bacterial Metabolism (1930), Preface. In 'Obituary Notice: Marjory Stephenson, 1885–1948', Biochemistry Journal (1950), 46:4, 380.
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[In the case of research director, Willis R. Whitney, whose style was to give talented investigators as much freedom as possible, you may define "serendipity" as] the art of profiting from unexpected occurrences. When you do things in that way you get unexpected results. Then you do something else and you get unexpected results in another line, and you do that on a third line and then all of a sudden you see that one of these lines has something to do with the other. Then you make a discovery that you never could have made by going on a direct road.
Quoted in Guy Suits, 'Willis Rodney Whitney', National Academy of Sciences, Biographical Memoirs (1960), 355.
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[Locating, from scratch, the gene related to a disease is like] trying to find a burned-out light bulb in a house located somewhere between the East and West coasts without knowing the state, much less the town or street the house is on.
Quoted in Philip Elmer-Dewitt, et al.,'The Genetic Revolution', Time magazine (17 Jan 1994), 46-53.
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[L]et us not overlook the further great fact, that not only does science underlie sculpture, painting, music, poetry, but that science is itself poetic. The current opinion that science and poetry are opposed is a delusion. ... On the contrary science opens up realms of poetry where to the unscientific all is a blank. Those engaged in scientific researches constantly show us that they realize not less vividly, but more vividly, than others, the poetry of their subjects. Whoever will dip into Hugh Miller's works on geology, or read Mr. Lewes's “Seaside Studies,” will perceive that science excites poetry rather than extinguishes it. And whoever will contemplate the life of Goethe will see that the poet and the man of science can co-exist in equal activity. Is it not, indeed, an absurd and almost a sacrilegious belief that the more a man studies Nature the less he reveres it? Think you that a drop of water, which to the vulgar eye is but a drop of water, loses anything in the eye of the physicist who knows that its elements are held together by a force which, if suddenly liberated, would produce a flash of lightning? Think you that what is carelessly looked upon by the uninitiated as a mere snow-flake, does not suggest higher associations to one who has seen through a microscope the wondrously varied and elegant forms of snow-crystals? Think you that the rounded rock marked with parallel scratches calls up as much poetry in an ignorant mind as in the mind of a geologist, who knows that over this rock a glacier slid a million years ago? The truth is, that those who have never entered upon scientific pursuits know not a tithe of the poetry by which they are surrounded. Whoever has not in youth collected plants and insects, knows not half the halo of interest which lanes and hedge-rows can assume. Whoever has not sought for fossils, has little idea of the poetical associations that surround the places where imbedded treasures were found. Whoever at the seaside has not had a microscope and aquarium, has yet to learn what the highest pleasures of the seaside are. Sad, indeed, is it to see how men occupy themselves with trivialities, and are indifferent to the grandest phenomena—care not to understand the architecture of the Heavens, but are deeply interested in some contemptible controversy about the intrigues of Mary Queen of Scots!—are learnedly critical over a Greek ode, and pass by without a glance that grand epic written by the finger of God upon the strata of the Earth!
Education: Intellectual, Moral, and Physical (1889), 82-83.
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[M]y work, which I've done for a long time, was not pursued in order to gain the praise I now enjoy, but chiefly from a craving after knowledge, which I notice resides in me more than in most other men. And therewithal, whenever I found out anything remarkable, I have thought it my duty to put down my discovery on paper, so that all ingenious people might be informed thereof.
Letter (27 Jun 1716) thanking the University of Louvain for ending him a medal designed in honour of his research. (Leeuwenhoek was then in his 84th year.) As cited by Charles-Edward Amory Winslow in The Conquest of Epidemic Disease: A Chapter in the History of Ideas (), 156.
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[On the practical applications of particle physics research with the Large Hadron Collider.] Sometimes the public says, 'What's in it for Numero Uno? Am I going to get better television reception? Am I going to get better Internet reception?' Well, in some sense, yeah. ... All the wonders of quantum physics were learned basically from looking at atom-smasher technology. ... But let me let you in on a secret: We physicists are not driven to do this because of better color television. ... That's a spin-off. We do this because we want to understand our role and our place in the universe.
As quoted in Alan Boyle, 'Discovery of Doom? Collider Stirs Debate', article (8 Sep 2008) on a msnbc.com web page. The article writer included the information that Kaku noted that past discoveries from the world of particle physics ushered in many of the innovations we enjoy today, ranging from satellite communications and handheld media players to medical PET scanners (which put antimatter to practical use)."
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[Otto Struve] made the remark once that he never looked at the spectrum of a star, any star, where he didn’t find something important to work on.
'Oral History Transcript: Dr. William Wilson Morgan' (8 Aug 1978) in the Niels Bohr Library & Archives.
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[Pure research] is worth every penny it costs.
Quoted in 'Moon-Struck Scientist,' New York Times (27 Apr 1961), 42.

[Richard Drew] always encouraged his people to pursue ideas… He said, “If it’s a dumb idea, you’ll find out. You’ll smack into that brick wall, then you’ll stagger back and see another opportunity that you wouldn’t have seen otherwise.”
Art Fry
As quoted in W. James McNerney Jr., A Century of Innovation: The 3M Story (2002), 68. (Note: The quote is in the words of Art Fry, as a recollection, and not necessarily a verbatim quote as spoken by Drew.)
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[Richard Drew] created a greenhouse environment—a skunkworks—where we could do anything, try anything. When you’re an oddball in a permissive environment, very often things turn out well.
As quoted in W. James McNerney Jr., A Century of Innovation: The 3M Story (2002), 26.
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[The purpose of flight research] is to separate the real from the imagined problems and to make known the overlooked and the unexpected.
Description of the purpose of the X-15 program given in a meeting at the Langley Research Center (Oct 1956). Quoted in Michael H. Gorn, Expanding the Envelope (2001), 3.
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[There] are cases where there is no dishonesty involved but where people are tricked into false results by a lack of understanding about what human beings can do to themselves in the way of being led astray by subjective effects, wishful thinking or threshold interactions. These are examples of pathological science. These are things that attracted a great deal of attention. Usually hundreds of papers have been published upon them. Sometimes they have lasted for fifteen or twenty years and then they gradually die away.
[Coining the term “pathological science” for the self-deceiving application of science to a phenomenon that doesn't exist.]
From a Colloquium at The Knolls Research Laboratory (18 Dec 1953). Transcribed and edited by R. N. Hall. In General Electric Laboratories, Report No. 68-C-035 (April 1968).
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[T]he history of science has proved that fundamental research is the lifeblood of individual progress and that the ideas that lead to spectacular advances spring from it.
In J. Edwin Holmström, Records and Research in Engineering and Industrial Science (1956), 7.
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[T]he yeoman's work in any science, and especially physics, is done by the experimentalist, who must keep the theoreticians honest.
Hyperspace: A Scientific Odyssey Through Parallel Universes, Time Warps, and The Tenth Dimension (1994), 314.
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… the icy layers of the upper atmosphere contain conundrums enough to be worthy of humanity's greatest efforts.
Begrüssungsworte', Fourth conference of the International Commission for Scientific Aeronautics, St. Petersberg, 1904 (1905), 28-35. Quoted in Peter Lynch, The Emergence of Numerical Weather Prediction (2006), 97.
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…we are all inclined to ... direct our inquiry not by the matter itself, but by the views of our opponents; and, even when interrogating oneself, one pushes the inquiry only to the point at which one can no longer offer any opposition. Hence a good inquirer will be one who is ready in bringing forward the objections proper to the genus, and that he will be when he has gained an understanding of the differences.
Aristotle
'On the Heavens', The Works of Aristotle editted by William David Ross and John Alexander Smith (1930), Vol. 2, 15.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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- 100 -
Sophie Germain
Gertrude Elion
Ernest Rutherford
James Chadwick
Marcel Proust
William Harvey
Johann Goethe
John Keynes
Carl Gauss
Paul Feyerabend
- 90 -
Antoine Lavoisier
Lise Meitner
Charles Babbage
Ibn Khaldun
Euclid
Ralph Emerson
Robert Bunsen
Frederick Banting
Andre Ampere
Winston Churchill
- 80 -
John Locke
Bronislaw Malinowski
Bible
Thomas Huxley
Alessandro Volta
Erwin Schrodinger
Wilhelm Roentgen
Louis Pasteur
Bertrand Russell
Jean Lamarck
- 70 -
Samuel Morse
John Wheeler
Nicolaus Copernicus
Robert Fulton
Pierre Laplace
Humphry Davy
Thomas Edison
Lord Kelvin
Theodore Roosevelt
Carolus Linnaeus
- 60 -
Francis Galton
Linus Pauling
Immanuel Kant
Martin Fischer
Robert Boyle
Karl Popper
Paul Dirac
Avicenna
James Watson
William Shakespeare
- 50 -
Stephen Hawking
Niels Bohr
Nikola Tesla
Rachel Carson
Max Planck
Henry Adams
Richard Dawkins
Werner Heisenberg
Alfred Wegener
John Dalton
- 40 -
Pierre Fermat
Edward Wilson
Johannes Kepler
Gustave Eiffel
Giordano Bruno
JJ Thomson
Thomas Kuhn
Leonardo DaVinci
Archimedes
David Hume
- 30 -
Andreas Vesalius
Rudolf Virchow
Richard Feynman
James Hutton
Alexander Fleming
Emile Durkheim
Benjamin Franklin
Robert Oppenheimer
Robert Hooke
Charles Kettering
- 20 -
Carl Sagan
James Maxwell
Marie Curie
Rene Descartes
Francis Crick
Hippocrates
Michael Faraday
Srinivasa Ramanujan
Francis Bacon
Galileo Galilei
- 10 -
Aristotle
John Watson
Rosalind Franklin
Michio Kaku
Isaac Asimov
Charles Darwin
Sigmund Freud
Albert Einstein
Florence Nightingale
Isaac Newton

New Book


The Simpsons and their Mathematical Secrets,
by Simon Singh

Cleverly embedded in many Simpsons plots are subtle references to mathematics, because the show's brilliant comedy writers with advanced degrees in math or science. Singh offers an entirely new insight into the most successful show in television history.