A sound Physics of the Earth should include all the primary considerations of the earth's atmosphere, of the characteristics and continual changes of the earth's external crust, and finally of the origin and development of living organisms. These considerations naturally divide the physics of the earth into three essential parts, the first being a theory of the atmosphere, or Meteorology, the second, a theory of the earth's external crust, or Hydrogeology, and the third, a theory of living organisms, or Biology.

All known living bodies are sharply divided into two special kingdoms, based upon the essential differences which distinguish animals from plants, and in spite of what has been said, I am convinced that these two kingdoms do not really merge into one another at any point.

Among natural bodies some have, and some have not, life; and by life we mean the faculties of self-nourishment, self-growth and self-decay. Thus every natural body partaking of life may be regarded as an essential existence; ... but then it is an existence only in combination. ... And since the organism is such a combination, being possessed of life, it cannot be the Vital Principle. Therefore it follows that the Vital Principle most be an essence, as being the form of a natural body, holding life in potentiality; but essence is a reality (entetechie). The Vital Principle is the original reality of a natural body endowed with potential life ; this, however, is to be understood only of a body which may be organized. Thus the parts even of plants are organs, but they are organs that are altogether simple; as the leaf which is the covering of the pericarp, the pericarp of the fruit. If, then, there be any general formula for every kind of Vital Principle, it is—tthe primary reality of an organism.

An organized product of nature is that in which all the parts are mutually ends and means.

Biophilia, if it exists, and I believe it exists, is the innately emotional affiliation of human beings to other living organisms.

Every component of the organism is as much of an organism as every other part.

For the philosopher, order is the entirety of repetitions manifested, in the form of types or of laws, by perceived objects. Order is an intelligible relation. For the biologist, order is a sequence in space and time. However, according to Plato, all things arise out of their opposites. Order was born of the original disorder, and the long evolution responsible for the present biological order necessarily had to engender disorder.
An organism is a molecular society, and biological order is a kind of social order. Social order is opposed to revolution, which is an abrupt change of order, and to anarchy, which is the absence of order.
I am presenting here today both revolution and anarchy, for which I am fortunately not the only one responsible. However, anarchy cannot survive and prosper except in an ordered society, and revolution becomes sooner or later the new order. Viruses have not failed to follow the general law. They are strict parasites which, born of disorder, have created a very remarkable new order to ensure their own perpetuation.

From all we have learnt about the structure of living matter, we must be prepared to find it working in a manner that cannot be reduced to the ordinary laws of physics. And that not on the ground that there is any 'new force' or what not, directing the behavior of the single atoms within a living organism, but because the construction is different from anything we have yet tested in the physical laboratory.

Harvard Law: Under the most rigorously controlled conditions of pressure, temperature, humidity, and other variables, the organism will do as it damn well pleases.

However, on many occasions, I examined normal blood and normal tissues and there was no possibility of overlooking bacteria or confusing them with granular masses of equal size. I never found organisms. Thus, I conclude that bacteria do not occur in healthy human or animal tissues.

In a purely technical sense, each species of higher organism—beetle, moss, and so forth, is richer in information than a Caravaggio painting, Mozart symphony, or any other great work of art.

It is often said that all the conditions for the first production of a living organism are now present, which could have ever been present. But if (and oh! what a big if!) we could conceive in some warm pond, with all sorts of ammonia and phosphoric salts, light, heat, electricity, &c., present, that a proteine compound was chemically formed ready to undergo still more complex changes, at the present day such matter would be instantly devoured or absorbed, which would not have been the case before living creatures were formed.

It may very properly be asked whether the attempt to define distinct species, of a more or less permanent nature, such as we are accustomed to deal with amongst the higher plants and animals, is not altogether illusory amongst such lowly organised forms of life as the bacteria. No biologist nowadays believes in the absolute fixity of species ... but there are two circumstances which here render the problem of specificity even more difficult of solution. The bacteriologist is deprived of the test of mutual fertility or sterility, so valuable in determining specific limits amongst organisms in which sexual reproduction prevails. Further, the extreme rapidity with which generation succeeds generation amongst bacteria offers to the forces of variation and natural selection a field for their operation wholly unparalleled amongst higher forms of life.

Life is order, death is disorder. A fundamental law of Nature states that spontaneous chemical changes in the universe tend toward chaos. But life has, during milliards of years of evolution, seemingly contradicted this law. With the aid of energy derived from the sun it has built up the most complicated systems to be found in the universe—living organisms. Living matter is characterized by a high degree of chemical organisation on all levels, from the organs of large organisms to the smallest constituents of the cell. The beauty we experience when we enjoy the exquisite form of a flower or a bird is a reflection of a microscopic beauty in the architecture of molecules.

Most classifications, whether of inanimate objects or of organisms, are hierarchical. There are 'higher' and 'lower' categories, there are higher and lower ranks. What is usually overlooked is that the use of the term 'hierarchy' is ambiguous, and that two fundamentally different kinds of arrangements have been designated as hierarchical. A hierarchy can be either exclusive or inclusive. Military ranks from private, corporal, sergeant, lieutenant, captain, up to general are a typical example of an exclusive hierarchy. A lower rank is not a subdivision of a higher rank; thus, lieutenants are not a subdivision of captains. The scala naturae, which so strongly dominated thinking from the sixteenth to the eighteenth century, is another good illustration of an exclusive hierarchy. Each level of perfection was considered an advance (or degradation) from the next lower (or higher) level in the hierarchy, but did not include it.

Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.

Plasticity is a double-edged sword; the more flexible an organism is the greater the variety of maladaptive, as well as adaptive, behaviors it can develop; the more teachable it is the more fully it can profit from the experiences of its ancestors and associates and the more it risks being exploited by its ancestors and associates.

The assumptions of population thinking are diametrically opposed to those of the typologist. The populationist stresses the uniqueness of everything in the organic world. What is true for the human species,–that no two individuals are alike, is equally true for all other species of animals and plants ... All organisms and organic phenomena are composed of unique features and can be described collectively only in statistical terms. Individuals, or any kind of organic entities, form populations of which we can determine the arithmetic mean and the statistics of variation. Averages are merely statistical abstractions, only the individuals of which the populations are composed have reality. The ultimate conclusions of the population thinker and of the typologist are precisely the opposite. For the typologist, the type (eidos) is real and the variation. an illusion, while for the populationist the type (average) is an abstraction and only the variation is real. No two ways of looking at nature could be more different.

The cell, this elementary keystone of living nature, is far from being a peculiar chemical giant molecule or even a living protein and as such is not likely to fall prey to the field of an advanced chemistry. The cell is itself an organism, constituted of many small units of life.

The chemical differences among various species and genera of animals and plants are certainly as significant for the history of their origins as the differences in form. If we could define clearly the differences in molecular constitution and functions of different kinds of organisms, there would be possible a more illuminating and deeper understanding of question of the evolutionary reactions of organisms than could ever be expected from morphological considerations.

The development of an organism … may be considered as the execution of a 'developmental program' present in the fertilized egg. … A central task of developmental biology is to discover the underlying algorithm from the course of development.

The organism cannot be regarded as simply the passive object of autonomous internal and external forces; it is also the subject of its own evolution.
Co-author with American biologist Richard Charles Lewontin (1929- )

The physiological combustion theory takes as its starting point the fundamental principle that the amount of heat that arises from the combustion of a given substance is an invariable quantity–i.e., one independent of the circumstances accompanying the combustion–from which it is more specifically concluded that the chemical effect of the combustible materials undergoes no quantitative change even as a result of the vital process, or that the living organism, with all its mysteries and marvels, is not capable of generating heat out of nothing.

Until that afternoon, my thoughts on planetary atmospheres had been wholly concerned with atmospheric analysis as a method of life detection and nothing more. Now that I knew the composition of the Martian atmosphere was so different from that of our own, my mind filled with wonderings about the nature of the Earth. If the air is burning, what sustains it at a constant composition? I also wondered about the supply of fuel and the removal of the products of combustion. It came to me suddenly, just like a flash of enlightenment, that to persist and keep stable, something must be regulating the atmosphere and so keeping it at its constant composition. Moreover, if most of the gases came from living organisms, then life at the surface must be doing the regulation.

When... the biologist is confronted with the fact that in the organism the parts are so adapted to each other as to give rise to a harmonious whole; and that the organisms are endowed with structures and instincts calculated to prolong their life and perpetuate their race, doubts as to the adequacy of a purely physiochemical viewpoint in biology may arise. The difficulties besetting the biologist in this problem have been rather increased than diminished by the discovery of Mendelian heredity, according to which each character is transmitted independently of any other character. Since the number of Mendelian characters in each organism is large, the possibility must be faced that the organism is merely a mosaic of independent hereditary characters. If this be the case the question arises: What moulds these independent characters into a harmonious whole? The vitalist settles this question by assuming the existence of a pre-established design for each organism and of a guiding 'force' or 'principle' which directs the working out of this design. Such assumptions remove the problem of accounting for the harmonious character of the organism from the field of physics or chemistry. The theory of natural selection invokes neither design nor purpose, but it is incomplete since it disregards the physiochemical constitution of living matter about which little was known until recently.