...for the animals, which we resemble and which would be our equals if we did not have reason, do not reflect upon the actions or the passions of their external or internal senses, and do not know what is color, odor or sound, or if there is any differences between these objects, to which they are moved rather than moving themselves there. This comes about by the force of the impression that the different objects make on their organs and on their senses, for they cannot discern if it is more appropriate to go and drink or eat or do something else, and they do not eat or drink or do anything else except when the presence of objects or the animal imagination [l'imagination brutalle], necessitates them and transports them to their objects, without their knowing what they do, whether good or bad; which would happen to us just as to them if we were destitute of reason, for they have no enlightenment except what they must have to take their nourishment and to serve us for the uses to which God has destined them.
[Arguing the uniqueness of man by regarding animals to be merely automatons.].

I. Animals have an electricity peculiar to themselves to which the name animal electricity is given.
II. The organs in which animal electricity acts above all others, and by which it is distributed throughout the whole body, are the nerves, and the most important organ of secretion is the brain.

A function to each organ, and each organ to its own function, is the law of all organization.

A man in twenty-four hours converts as much as seven ounces of carbon into carbonic acid; a milch cow will convert seventy ounces, and a horse seventy-nine ounces, solely by the act of respiration. That is, the horse in twenty-four hours burns seventy-nine ounces of charcoal, or carbon, in his organs of respiration to supply his natural warmth in that time ..., not in a free state, but in a state of combination.

A nutritive centre, anatomically considered, is merely a cell, the nucleus of which is the permanent source of successive broods of young cells, which from time to time fill the cavity of their parent, and carrying with them the cell wall of the parent, pass off in certain directions, and under various forms, according to the texture or organ of which their parent forms a part.

A physician is obligated to consider more than a diseased organ, more than even the whole man—he must view the man in his world.

All living organisms are but leaves on the same tree of life. The various functions of plants and animals and their specialized organs are manifestations of the same living matter. This adapts itself to different jobs and circumstances, but operates on the same basic principles. Muscle contraction is only one of these adaptations. In principle it would not matter whether we studied nerve, kidney or muscle to understand the basic principles of life. In practice, however, it matters a great deal.

Among natural bodies some have, and some have not, life; and by life we mean the faculties of self-nourishment, self-growth and self-decay. Thus every natural body partaking of life may be regarded as an essential existence; ... but then it is an existence only in combination. ... And since the organism is such a combination, being possessed of life, it cannot be the Vital Principle. Therefore it follows that the Vital Principle most be an essence, as being the form of a natural body, holding life in potentiality; but essence is a reality (entetechie). The Vital Principle is the original reality of a natural body endowed with potential life ; this, however, is to be understood only of a body which may be organized. Thus the parts even of plants are organs, but they are organs that are altogether simple; as the leaf which is the covering of the pericarp, the pericarp of the fruit. If, then, there be any general formula for every kind of Vital Principle, it is—tthe primary reality of an organism.

Analogue. A part or organ in one animal which has the same function as another part or organ in a different animal.

As an adult she had her organs removed one by one. Now she is a mere shell with symptoms where her organs used to be.
Written as an intern on one of his patient's charts; commentary on the result of surgical treatment of non-organic disease.

As an organ is exercised, circulation is more particularly directed to it and is more readily performed in it. Consequently, all its secretions and excretions increase. The more an organ is exercised, the more it is nourished.

Constant, or free, life is the third form of life; it belongs to the most highly organized animals. In it, life is not suspended in any circumstance, it unrolls along a constant course, apparently indifferent to the variations in the cosmic environment, or to the changes in the material conditions that surround the animal. Organs, apparatus, and tissues function in an apparently uniform manner, without their activity undergoing those considerable variations exhibited by animals with an oscillating life. This because in reality the internal environment that envelops the organs, the tissues, and the elements of the tissues does not change; the variations in the atmosphere stop there, so that it is true to say that physical conditions of the environment are constant in the higher animals; it is enveloped in an invariable medium, which acts as an atmosphere of its own in the constantly changing cosmic environment. It is an organism that has placed itself in a hot-house. Thus the perpetual changes in the cosmic environment do not touch it; it is not chained to them, it is free and independent.

Don’t take your organs to heaven with you. Heaven knows we need them here.
[Slogan advocating organ donations.]

First Law
In every animal which has not passed the limit of its development, a more frequent and continuous use of any organ gradually strengthens, develops and enlarges that organ, and gives it a power proportional to the length of time it has been so used; while the permanent disuse of any organ imperceptibly weakens and deteriorates it, and progressively diminishes its functional capacity, until it finally disappears.

Five per cent vision is better than no vision at all. Five per cent hearing is better than no hearing at all. Five per cent flight efficiency is better than no flight at all. It is thoroughly believable that every organ or apparatus that we actually see is the product of a smooth trajectory through animal space, a trajectory in which every intermediate stage assisted survival and reproduction.
[Rebutting the Creationist assertion that fully developed organs could not have arisen 'by chance.']

Fortunately Nature herself seems to have prepared for us the means of supplying that want which arises from the impossibility of making certain experiments on living bodies. The different classes of animals exhibit almost all the possible combinations of organs: we find them united, two and two, three and three, and in all proportions; while at the same time it may be said that there is no organ of which some class or some genus is not deprived. A careful examination of the effects which result from these unions and privations is therefore sufficient to enable us to form probable conclusions respecting the nature and use of each organ, or form of organ. In the same manner we may proceed to ascertain the use of the different parts of the same organ, and to discover those which are essential, and separate them from those which are only accessory. It is sufficient to trace the organ through all the classes which possess it, and to examine what parts constantly exist, and what change is produced in the respective functions of the organ, by the absence of those parts which are wanting in certain classes.

Homologue. The same organ in different animals under every variety of form and function.

I know that certain minds would regard as audacious the idea of relating the laws which preside over the play of our organs to those laws which govern inanimate bodies; but, although novel, this truth is none the less incontestable. To hold that the phenomena of life are entirely distinct from the general phenomena of nature is to commit a grave error, it is to oppose the continued progress of science.

I would clarify that by ‘animal’ I understand a being that has feeling and that is capable of exercising life functions through a principle called soul; that the soul uses the body's organs, which are true machines, by virtue of its being the principal cause of the action of each of the machine's parts; and that although the placement that these parts have with respect to one another does scarcely anything else through the soul's mediation than what it does in pure machines, the entire machine nonetheless needs to be activated and guided by the soul in the same way as an organ, which, although capable of rendering different sounds through the placement of the parts of which it is composed, nonetheless never does so except through the guidance of the organist.

If we reflect that a small creature such as this is provided, not only with external members, but also with intestines and other organs, we have no reason to doubt that a like creature, even if a thousand million times smaller, may already be provided with all its external and internal organs... though they may be hidden from our eyes. For, if we consider the external and internal organs of animalcules which are so small that a thousand million of them together would amount to the size of a coarse grain of sand, it may well be, however incomprehensible and unsearchable it may seem to us, that an animalcule from the male seed of whatever members of the animal kingdom, contains within itself... all the limbs and organs which an animal has when it is born.

It is in this mutual dependence of the functions and the aid which they reciprocally lend one another that are founded the laws which determine the relations of their organs and which possess a necessity equal to that of metaphysical or mathematical laws, since it is evident that the seemly harmony between organs which interact is a necessary condition of existence of the creature to which they belong and that if one of these functions were modified in a manner incompatible with the modifications of the others the creature could no longer continue to exist.

It is not the organs—that is, the character and form of the animal's bodily parts—that have given rise to its habits and particular structures. It is the habits and manner of life and the conditions in which its ancestors lived that have in the course of time fashioned its bodily form, its organs and qualities.

Life is order, death is disorder. A fundamental law of Nature states that spontaneous chemical changes in the universe tend toward chaos. But life has, during milliards of years of evolution, seemingly contradicted this law. With the aid of energy derived from the sun it has built up the most complicated systems to be found in the universe—living organisms. Living matter is characterized by a high degree of chemical organisation on all levels, from the organs of large organisms to the smallest constituents of the cell. The beauty we experience when we enjoy the exquisite form of a flower or a bird is a reflection of a microscopic beauty in the architecture of molecules.

Nature ... tends to repeat the same organs in the same number and in the same relations, and varies to infinity only their form. In accordance with this principle I shall have to draw my conclusions, in the determining the bones of the fish's skull, not from a consideration of their form, but from a consideration of their connections.

Nature, ... in order to carry out the marvelous operations [that occur] in animals and plants has been pleased to construct their organized bodies with a very large number of machines, which are of necessity made up of extremely minute parts so shaped and situated as to form a marvelous organ, the structure and composition of which are usually invisible to the naked eye without the aid of a microscope. ... Just as Nature deserves praise and admiration for making machines so small, so too the physician who observes them to the best of his ability is worthy of praise, not blame, for he must also correct and repair these machines as well as he can every time they get out of order.

One can truly say that the irresistible progress of natural science since the time of Galileo has made its first halt before the study of the higher parts of the brain, the organ of the most complicated relations of the animal to the external world. And it seems, and not without reason, that now is the really critical moment for natural science; for the brain, in its highest complexity—the human brain—which created and creates natural science, itself becomes the object of this science.

Organs, faculties, powers, capacities, or whatever else we call them; grow by use and diminish from disuse, it is inferred that they will continue to do so. And if this inference is unquestionable, then is the one above deduced from it—that humanity must in the end become completely adapted to its conditions—unquestionable also. Progress, therefore, is not an accident, but a necessity.

Second Law
All the acquisitions or losses wrought by nature on individuals, through the influence of the environment in which their race has long been placed, and hence through the influence of the predominant use or permanent disuse of any organ; all these are preserved by reproduction to the new individuals which arise, provided that the acquired modifications are common to both sexes, or at least to the individuals which produce the young.

The fact remains that, if the supply of energy failed, modern civilization would come to an end as abruptly as does the music of an organ deprived of wind.

The next care to be taken, in respect of the Senses, is a supplying of their infirmities with Instruments, and, as it were, the adding of artificial Organs to the natural; this in one of them has been of late years accomplisht with prodigious benefit to all sorts of useful knowledge, by the invention of Optical Glasses. By the means of Telescopes, there is nothing so far distant but may be represented to our view; and by the help of Microscopes, there is nothing so small, as to escape our inquiry; hence there is a new visible World discovered to the understanding. By this means the Heavens are open'd, and a vast number of new Stars, and new Motions, and new Productions appear in them, to which all the ancient Astronomers were utterly Strangers. By this the Earth it self, which lyes so neer us, under our feet, shews quite a new thing to us, and in every little particle of its matter, we now behold almost as great a variety of creatures as we were able before to reckon up on the whole Universe it self.

The specific character of the greater part of the toxins which are known to us (I need only instance such toxins as those of tetanus and diphtheria) would suggest that the substances produced for effecting the correlation of organs within the body, through the intermediation of the blood stream, might also belong to this class, since here also specificity of action must be a distinguishing characteristic. These chemical messengers, however, or 'hormones' (from όρμάω, I excite or arouse), as we might call them, have to be carried from the organ where they are produced to the organ which they affect by means of the blood stream and the continually recurring physiological needs of the organism must determine their repeated production and circulation through the body.

There are those who say that the human kidney was created to keep the blood pure, or more precisely, to keep our internal environment in an ideal balanced state. This I must deny. I grant that the human kidney is a marvelous organ, but I cannot grant that it was purposefully designed to excrete urine or to regulate the composition of the blood or to subserve the physiological welfare of Homo sapiens in any sense. Rather I contend that the human kidney manufactures the kind of urine that it does, and it maintains the blood in the composition which that fluid has, because this kidney has a certain functional architecture; and it owes that architecture not to design or foresight or to any plan, but to the fact that the earth is an unstable sphere with a fragile crust, to the geologic revolutions that for six hundred million years have raised and lowered continents and seas, to the predacious enemies, and heat and cold, and storms and droughts; to the unending succession of vicissitudes that have driven the mutant vertebrates from sea into fresh water, into desiccated swamps, out upon the dry land, from one habitation to another, perpetually in search of the free and independent life, perpetually failing, for one reason or another, to find it.

This integrative action in virtue of which the nervous system unifies from separate organs an animal possessing solidarity, an individual, is the problem before us.

Thus it might be said, that the vegetable is only the sketch, nor rather the ground-work of the animal; that for the formation of the latter, it has only been requisite to clothe the former with an apparatus of external organs, by which it might be connected with external objects.
From hence it follows, that the functions of the animal are of two very different classes. By the one (which is composed of an habitual succession of assimilation and excretion) it lives within itself, transforms into its proper substance the particles of other bodies, and afterwards rejects them when they are become heterogeneous to its nature. By the other, it lives externally, is the inhabitant of the world, and not as the vegetable of a spot only; it feels, it perceives, it reflects on its sensations, it moves according to their influence, and frequently is enabled to communicate by its voice its desires, and its fears, its pleasures, and its pains.
The aggregate of the functions of the first order, I shall name the organic life, because all organized beings, whether animal or vegetable, enjoy it more or less, because organic texture is the sole condition necessary to its existence. The sum of the functions of the second class, because it is exclusively the property of the animal, I shall denominate the animal life.

Vertebrate development consists in the formation, in the median plane, of four leaflets two of which are above the axis and two below. During this evolution the germ subdivides in layers, and this has the effect of dividing the primordial tubes into secondary masses. The latter, included in the other masses, are the fundamental organs with the faculty of forming all the other organs.

We know that nature invariably uses the same materials in its operations. Its ingeniousness is displayed only in the variation of form. Indeed, as if nature had voluntarily confined itself to using only a few basic units, we observe that it generally causes the same elements to reappear, in the same number, in the same circumstances, and in the same relationships to one another. If an organ happens to grow in an unusual manner, it exerts a considerable influence on adjacent parts, which as a result fail to reach their standard degree of development.