...while science gives us implements to use, science alone does not determine for what ends they will be employed. Radio is an amazing invention. Yet now that it is here, one suspects that Hitler never could have consolidated his totalitarian control over Germany without its use. One never can tell what hands will reach out to lay hold on scientific gifts, or to what employment they will be put. Ever the old barbarian emerges, destructively using the new civilization.

Dilbert: It took weeks but I've calculated a new theory about the origin of the universe. According to my calculations it didn't start with a "Big Bang" at all—it was more of "Phhbwt" sound. You may be wondering about the practical applications of the "Little Phhbwt" theory.
Dogbert: I was wondering when you'll go away.

Dilbert: Wow! According to my computer simulation, it should be possible to create new life forms from common household chemicals
Dogbert: This raises some thorny issues.
Dilbert: You mean legal, ethical and religious issues?
Dogbert: I was thinking about parking spaces.

Les Leucocytes Et L'esprit De Sacrif1ce. — Il semble, d'après les recherches de De Bruyne (Phagocytose, 1895) et de ceux qui le citent, que les leucocytes des Lamellibranches — probablement lorsqu'ils ont phagocyté, qu'ils se sont chargés de résidus et de déchets, qu'ils ont, en un mot, accompli leur rôle et bien fait leur devoir — sortent du corps de l'animal et vont mourir dans le milieu ambiant. Ils se sacrifient. Après avoir si bien servi l'organisme par leur activité, ils le servent encore par leur mort en faisant place aux cellules nouvelles, plus jeunes.
N'est-ce pas la parfaite image du désintéressement le plus noble, et n'y a-t-il point là un exemple et un modèle? Il faut s'en inspirer: comme eux, nous sommes les unités d'un grand corps social; comme eux, nous pouvons le servir et envisager la mort avec sérénité, en subordonnant notre conscience individuelle à la conscience collective. (30 Jan 1896)
Leukocytes and The Spirit Of Sacrifice. - It seems, according to research by De Bruyne (Phagocytosis, 1885) and those who quote it, that leukocytes of Lamellibranches [bivalves] - likely when they have phagocytized [ingested bacteria], as they become residues and waste, they have, in short, performed their role well and done their duty - leave the body of the animal and will die in the environment. They sacrifice themselves. Having so well served the body by their activities, they still serve in their death by making room for new younger cells.
Isn't this the perfect image of the noblest selflessness, and thereby presents an example and a model? It should be inspiring: like them, we are the units of a great social body, like them, we can serve and contemplate death with equanimity, subordinating our individual consciousness to collective consciousness.

[About Sir Roderick Impey Murchison:] The enjoyments of elegant life you early chose to abandon, preferring to wander for many successive years over the rudest portions of Europe and Asia—regions new to Science—in the hope, happily realized, of winning new truths.
By a rare union of favourable circumstances, and of personal qualifications equally rare, you have thus been enabled to become the recognized Interpreter and Historian (not without illustrious aid) of the Silurian Period.

A new theory is guilty until proven innocent, and the pre-existing theory innocent until proven guilty ... Continental drift was guilty until proven innocent.

Accurate and minute measurement seems to the non-scientific imagination, a less lofty and dignified work than looking for something new. But nearly all the grandest discoveries of science have been but the rewards of accurate measurement and patient long-continued labour in the minute sifting of numerical results.

Alike fantastic, if too new, or old;
Be not the first by whom the new are try'd,
Not yet the last to lay the old aside.

As evolutionary time is measured, we have only just turned up and have hardly had time to catch breath, still marveling at our thumbs, still learning to use the brand-new gift of language. Being so young, we can be excused all sorts of folly and can permit ourselves the hope that someday, as a species, we will begin to grow up.

As the component parts of all new machines may be said to be old[,] it is a nice discriminating judgment, which discovers that a particular arrangement will produce a new and desired effect. ... Therefore, the mechanic should sit down among levers, screws, wedges, wheels, etc. like a poet among the letters of the alphabet, considering them as the exhibition of his thoughts; in which a new arrangement transmits a new idea to the world.

Between every two pine trees there is a door leading to a new way of life.

Descartes constructed as noble a road of science, from the point at which he found geometry to that to which he carried it, as Newton himself did after him. ... He carried this spirit of geometry and invention into optics, which under him became a completely new art.

Electricity is but yet a new agent for the arts and manufactures, and, doubtless, generations unborn will regard with interest this century, in which it has been first applied to the wants of mankind.

Experiment is the sole source of truth. It alone can teach us something new; it alone can give us certainty.

For myself, I found that I was fitted for nothing so well as for the study of Truth; as having a mind nimble and versatile enough to catch the resemblances of things (which is the chief point) , and at the same time steady enough to fix and distinguish their subtler differences; as being gifted by nature with desire to seek, patience to doubt, fondness to meditate, slowness to assert, readiness to reconsider, carefulness to dispose and set in order; and as being a man that neither affects what is new nor admires what is old, and that hates every kind of imposture. So I thought my nature had a kind of familiarity and relationship with Truth.

For the birth of something new, there has to be a happening. Newton saw an apple fall; James Watt watched a kettle boil; Roentgen fogged some photographic plates. And these people knew enough to translate ordinary happenings into something new...

For this knowledge of right living, we have sought a new name... . As theology is the science of religious life, and biology the science of [physical] life ... so let Oekology be henceforth the science of [our] normal lives ... the worthiest of all the applied sciences which teaches the principles on which to found... healthy... and happy life.

Frequently, I have been asked if an experiment I have planned is pure or applied science; to me it is more important to know if the experiment will yield new and probably enduring knowledge about nature. If it is likely to yield such knowledge, it is, in my opinion, good fundamental research; and this is more important than whether the motivation is purely aesthetic satisfaction on the part of the experimenter on the one hand or the improvement of the stability of a high-power transistor on the other.

From my earliest childhood I nourished and cherished the desire to make a creditable journey in a new country, and write such a respectable account of its natural history as should give me a niche amongst the scientific explorers of the globe I inhabit, and hand my name down as a useful contributor of original matter.

I have been scientifically studying the traits and dispositions of the “lower animals” (so-called,) and contrasting them with the traits and dispositions of man. I find the result profoundly humiliating to me. For it obliges me to renounce my allegiance to the Darwinian theory of the Ascent of Man from the Lower Animals; since it now seems plain to me that that theory ought to be vacated in favor of a new and truer one, this new and truer one to be named the Descent of Man from the Higher Animals.

In less than eight years “The Origin of Species” has produced conviction in the minds of a majority of the most eminent living men of science. New facts, new problems, new difficulties as they arise are accepted, solved, or removed by this theory; and its principles are illustrated by the progress and conclusions of every well established branch of human knowledge.

In science the new is an advance; but in morals, as contradicting our inner ideals and historic idols, it is ever a retrogression.

In the new era, thought itself will be transmitted by radio.

It is a myth that the success of science in our time is mainly due to the huge amounts of money that have been spent on big machines. What really makes science grow is new ideas, including false ideas.

It is not enough to say that we cannot know or judge because all the information is not in. The process of gathering knowledge does not lead to knowing. A child's world spreads only a little beyond his understanding while that of a great scientist thrusts outward immeasurably. An answer is invariably the parent of a great family of new questions. So we draw worlds and fit them like tracings against the world about us, and crumple them when we find they do not fit and draw new ones.

It may be said “In research, if you know what you are doing, then you shouldn't be doing it.” In a sense, if the answer turns out to be exactly what you expected, then you have learned nothing new, although you may have had your confidence increased somewhat.

It was not noisy prejudice that caused the work of Mendel to lie dead for thirty years, but the sheer inability of contemporary opinion to distinguish between a new idea and nonsense.

It's becoming clear that in a sense the cosmos provides the only laboratory where sufficiently extreme conditions are ever achieved to test new ideas on particle physics. The energies in the Big Bang were far higher than we can ever achieve on Earth. So by looking at evidence for the Big Bang, and by studying things like neutron stars, we are in effect learning something about fundamental physics.

James Watt patented his steam engine on the eve of the American Revolution, consummating a relationship between coal and the new Promethean spirit of the age, and humanity made its first tentative steps into an industrial way of life that would, over the next two centuries, forever change the world.

Listen now for the sound that forevermore separates the old from the new.
[Introducing the beep-beep chirp transmitted by the Sputnik satellite.]

Many Species of Animals have been lost out of the World, which Philosophers and Divines are unwilling to admit, esteeming the Destruction of anyone Species a Dismembring of the Universe, and rendring the World imperfect; whereas they think the Divine Providence is especially concerned, and solicitous to secure and preserve the Works of the Creation. And truly so it is, as appears, in that it was so careful to lodge all Land Animals in the Ark at the Time of the general Deluge; and in that, of all Animals recorded in Natural Histories, we cannot say that there hath been anyone Species lost, no not of the most infirm, and most exposed to Injury and Ravine. Moreover, it is likely, that as there neither is nor can be any new Species of Animals produced, all proceeding from Seeds at first created; so Providence, without which one individual Sparrow falls not to the ground, doth in that manner watch over all that are created, that an entire Species shall not be lost or destroyed by any Accident. Now, I say, if these Bodies were sometimes the Shells and Bones of Fish, it will thence follow, that many Species have been lost out of the World... To which I have nothing to reply, but that there may be some of them remaining some where or other in the Seas, though as yet they have not come to my Knowledge. Far though they may have perished, or by some Accident been destroyed out of our Seas, yet the Race of them may be preserved and continued still in others.

Men, my brothers, men the workers, ever reaping something new,
That which they have done but earnest of the things which they shall do.

No engineer can go upon a new work and not find something peculiar, that will demand his careful reflection, and the deliberate consideration of any advice that he may receive; and nothing so fully reveals his incapacity as a pretentious assumption of knowledge, claiming to understand everything.

No one can read the history of astronomy without perceiving that Copernicus, Newton, Laplace, are not new men, or a new kind of men, but that Thales, Anaximenes, Hipparchus, Empodocles, Aristorchus, Pythagorus, Oenipodes, had anticipated them.

On 17th July there came to us at Potsdam the eagerly-awaited news of the trial of the atomic bomb in the [New] Mexican desert. Success beyond all dreams crowded this sombre, magnificent venture of our American allies. The detailed reports ... could leave no doubt in the minds of the very few who were informed, that we were in the presence of a new factor in human affairs, and possessed of powers which were irresistible.

On the whole, I cannot help saying that it appears to me not a little extraordinary, that a theory so new, and of such importance, overturning every thing that was thought to be the best established in chemistry, should rest on so very narrow and precarious a foundation, the experiments adduced in support of it being not only ambiguous or explicable on either hypothesis, but exceedingly few. I think I have recited them all, and that on which the greatest stress is laid, viz. That of the formation of water from the decomposition of the two kinds of air, has not been sufficiently repeated. Indeed it required so difficult and expensive an apparatus, and so many precautions in the use of it, that the frequent repetition of the experiment cannot be expected; and in these circumstances the practised experimenter cannot help suspecting the accuracy of the result and consequently the certainty of the conclusion.

One has to do something new in order to see something new.

One never finds fossil bones bearing no resemblance to human bones. Egyptian mummies, which are at least three thousand years old, show that men were the same then. The same applies to other mummified animals such as cats, dogs, crocodiles, falcons, vultures, oxen, ibises, etc. Species, therefore, do not change by degrees, but emerged after the new world was formed. Nor do we find intermediate species between those of the earlier world and those of today's. For example, there is no intermediate bear between our bear and the very different cave bear. To our knowledge, no spontaneous generation occurs in the present-day world. All organized beings owe their life to their fathers. Thus all records corroborate the globe's modernity. Negative proof: the barbaritY of the human species four thousand years ago. Positive proof: the great revolutions and the floods preserved in the traditions of all peoples.

One of the principal obstacles to the rapid diffusion of a new idea lies in the difficulty of finding suitable expression to convey its essential point to other minds. Words may have to be strained into a new sense, and scientific controversies constantly resolve themselves into differences about the meaning of words. On the other hand, a happy nomenclature has sometimes been more powerful than rigorous logic in allowing a new train of thought to be quickly and generally accepted.

Ours is a brand-new world of allatonceness [all-at-once-ness]. 'Time' has ceased, 'space' has vanished. We now live in a global village ... a simultaneous happening. ... The new electronic interdependence recreates the world in the image of a global village.
[Co-author with American social scientist, Quentin Fiore]

Rejoice when other scientists do not believe what you know to be true. It will give you extra time to work on it in peace. When they start claiming that they have discovered it before you, look for a new project.

Science is founded on uncertainty. Each time we learn something new and surprising, the astonishment comes with the realization that we were wrong before.

The advance of science is not comparable to the changes of a city, where old edifices are pitilessly torn down to give place to new, but to the continuous evolution of zoologic types which develop ceaselessly and end by becoming unrecognisable to the common sight, but where an expert eye finds always traces of the prior work of the centuries past. One must not think then that the old-fashioned theories have been sterile and vain.

The body of science is not, as it is sometimes thought, a huge coherent mass of facts, neatly arranged in sequence, each one attached to the next by a logical string. In truth, whenever we discover a new fact it involves the elimination of old ones. We are always, as it turns out, fundamentally in error.

The effect of a concept-driven revolution is to explain old things in new ways. The effect of a tool-driven revolution is to discover new things that have to be explained.

The historian of science may be tempted to claim that when paradigms change, the world itself changes with them. Led by a new paradigm, scientists adopt new instruments and look in new places. even more important, during revolutions, scientists see new and different things when looking with familiar instruments in places they have looked before. It is rather as if the professional community had been suddenly transported to another planet where familiar objects are seen in a different light and are joined by unfamiliar ones as well.

The indescribable pleasure—which pales the rest of life's joys—is abundant compensation for the investigator who endures the painful and persevering analytical work that precedes the appearance of the new truth, like the pain of childbirth. It is true to say that nothing for the scientific scholar is comparable to the things that he has discovered. Indeed, it would be difficult to find an investigator willing to exchange the paternity of a scientific conquest for all the gold on earth. And if there are some who look to science as a way of acquiring gold instead of applause from the learned, and the personal satisfaction associated with the very act of discovery, they have chosen the wrong profession.

The more we know about this universe, the more mysterious it is. The old world that Job knew was marvelous enough, and his description of its wonders is among the noblest poetry of the race, but today the new science has opened to our eyes vistas of mystery that transcend in their inexplicable marvel anything the ancients ever dreamed.

The new appears as a minority point of view, and hence is unpopular. The function of a university is to give it a sanctuary.

The progress of synthesis, or the building up of natural materials from their constituent elements, proceeds apace. Even some of the simpler albuminoids, a class of substances of great importance in the life process, have recently been artificially prepared. ... Innumerable entirely new compounds have been produced in the last century. The artificial dye-stuffs, prepared from materials occurring in coal-tar, make the natural colours blush. Saccharin, which is hundreds of times sweeter than sugar, is a purely artificial substance. New explosives, drugs, alloys, photographic substances, essences, scents, solvents, and detergents are being poured out in a continuous stream.

The same society which receives the rewards of technology must, as a cooperating whole, take responsibility for control. To deal with these new problems will require a new conservation. We must not only protect the countryside and save it from destruction, we must restore what has been destroyed and salvage the beauty and charm of our cities. Our conservation must be not just the classic conservation of protection and development, but a creative conservation of restoration and innovation. Its concern is not with nature alone, but with the total relation between man and the world around him. Its object is not just man's welfare, but the dignity of man's spirit.

The truly scientific mind is altogether unafraid of the new, and while having no mercy for ideas which have served their turn or shown their uselessness, it will not grudge to any unfamiliar conception its moment of full and friendly attention, hoping to expand rather than to minimize what small core of usefulness it may happen to contain.

There is no great harm in the theorist who makes up a new theory to fit a new event. But the theorist who starts with a false theory and then sees everything as making it come true is the most dangerous enemy of human reason.

There is no more convincing proof of the truth of a comprehensive theory than its power of absorbing and finding a place for new facts, and its capability of interpreting phenomena which had been previously looked upon as unaccountable anomalies. It is thus that the law of universal gravitation and the undulatory theory of light have become established and universally accepted by men of science. Fact after fact has been brought forward as being apparently inconsistent with them, and one alter another these very facts have been shown to be the consequences of the laws they were at first supposed to disprove. A false theory will never stand this test. Advancing knowledge brings to light whole groups of facts which it cannot deal with, and its advocates steadily decrease in numbers, notwithstanding the ability and scientific skill with which it may have been supported.

There is nothing new to be discovered in physics now. All that remains is more and more precise measurement.

This is the patent-age of new inventions
For killing bodies, and for saving souls,
All propagated with the best intentions;
Sir Humphrey Davy's lantern, by which coals
Are safely mined for in the mode he mentions,
Tombuctoo travels, voyages to the Poles,
Are ways to benefit mankind, as true,
Perhaps, as shooting them at Waterloo.

This paper contains much that is new and much that is true. Unfortunately, that which is true is not new and that which is new is not true.

To eliminate the discrepancy between men's plans and the results achieved, a new approach is necessary. Morphological thinking suggests that this new approach cannot be realized through increased teaching of specialized knowledge. This morphological analysis suggests that the essential fact has been overlooked that every human is potentially a genius. Education and dissemination of knowledge must assume a form which allows each student to absorb whatever develops his own genius, lest he become frustrated. The same outlook applies to the genius of the peoples as a whole.

To inquisitive minds like yours and mine the reflection that the quantity of human knowledge bears no proportion to the quantity of human ignorance must be in one view rather pleasing, viz., that though we are to live forever we may be continually amused and delighted with learning something new.

To introduce something altogether new would mean to begin all over, to become ignorant again, and to run the old, old risk of failing to learn.

To most ... of us, Russia was as mysterious and remote as the other side of the moon and not much more productive when it came to really new ideas or inventions. A common joke of the time [mid 1940s] said that the Russians could not surreptitiously introduce nuclear bombs in suitcases into the United States because they had not yet been able to perfect a suitcase.

To solve a problem is to create new problems, new knowledge immediately reveals new areas of ignorance, and the need for new experiments. At least, in the field of fast reactions, the experiments do not take very long to perform.

Too much openness and you accept every notion, idea, and hypothesis—which is tantamount to knowing nothing. Too much skepticism—especially rejection of new ideas before they are adequately tested—and you're not only unpleasantly grumpy, but also closed to the advance of science. A judicious mix is what we need.

Unless man can make new and original adaptations to his environment as rapidly as his science can change the environment, our culture will perish.

We are at our human finest, dancing with our minds, when there are more choices than two. Sometimes there are ten, even twenty different ways to go, all but one bound to be wrong, and the richness of the selection in such situations can lift us onto totally new ground.

We have reason not to be afraid of the machine, for there is always constructive change, the enemy of machines, making them change to fit new conditions.
We suffer not from overproduction but from undercirculation. You have heard of technocracy. I wish I had those fellows for my competitors. I'd like to take the automobile it is said they predicted could be made now that would last fifty years. Even if never used, this automobile would not be worth anything except to a junkman in ten years, because of the changes in men's tastes and ideas. This desire for change is an inherent quality in human nature, so that the present generation must not try to crystallize the needs of the future ones.
We have been measuring too much in terms of the dollar. What we should do is think in terms of useful materials—things that will be of value to us in our daily life.

We see it [the as-yet unseen, probable new planet, Neptune] as Columbus saw America from the coast of Spain. Its movements have been felt, trembling along the far-reaching line of our analysis with a certainty hardly inferior to that of ocular demonstration.

We set sail on this new sea because there is new knowledge to be gained, and new rights to be won, and they must be won and used for the progress of all people. For space science, like nuclear science and technology, has no conscience of its own. Whether it will become a force for good or ill depends on man, and only if the United States occupies a position of preeminence can we help decide whether this new ocean will be a sea of peace or a new terrifying theater of war.

Well-established theories collapse under the weight of new facts and observations which cannot be explained, and then accumulate to the point where the once useful theory is clearly obsolete.
[Using Thomas S. Kuhn's theories to frame his argument about the relationship beween science and technology: as new facts continue to accumulate, a new, more accurate paradigm must replace the old one.]

What opposite discoveries we have seen!
(Signs of true genius, and of empty pockets.)
One makes new noses, one a guillotine,
One breaks your bones, one sets them in their sockets;
But vaccination certainly has been
A kind antithesis to Congreve's rockets, ...

What we see in history is not a transformation, a passing of one race into another, but entirely new and perfect creations, which the ever-youthful productivity of nature sends forth from the invisible realm of Hades.

Where there is an observatory and a telescope, we expect that any eyes will see new worlds at once.

Yet as I cast my eye over the whole course of science I behold instances of false science, even more pretentious and popular than that of Einstein gradually fading into ineptitude under the searchlight; and I have no doubt that there will arise a new generation who will look with a wonder and amazement, deeper than now accompany Einstein, at our galaxy of thinkers, men of science, popular critics, authoritative professors and witty dramatists, who have been satisfied to waive their common sense in view of Einstein's absurdities.

[In relation to business:] Invention must be its keynote—a steady progression from one thing to another. As each in turn approaches a saturated market, something new must be produced.

[My father] advised me to sit every few months in my reading chair for an entire evening, close my eyes and try to think of new problems to solve. I took his advice very seriously and have been glad ever since that he did.

[Young] was afterwards accustomed to say, that at no period of his life was he particularly fond of repeating experiments, or even of very frequently attempting to originate new ones; considering that, however necessary to the advancement of science, they demanded a great sacrifice of time, and that when the fact was once established, that time was better employed in considering the purposes to which it might be applied, or the principles which it might tend to elucidate.

…it ought to be remembered that there is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success, than to take the lead in the introduction of a new order of things. Because the innovator has for enemies all those who have done well under the old conditions, and lukewarm defenders in those who may do well under the new.