And when with excellent Microscopes I discern in otherwise invisible Objects the Inimitable Subtlety of Nature's Curious Workmanship; And when, in a word, by the help of Anatomicall Knives, and the light of Chymicall Furnaces, I study the Book of Nature, and consult the Glosses of Aristotle, Epicurus, Paracelsus, Harvey, Helmont, and other learn'd Expositors of that instructive Volumne; I find my self oftentimes reduc'd to exclaim with the Psalmist, How manifold are thy works, O Lord? In wisdom hast thou made them all.

I have tried to show why I believe that the biologist is the most romantic figure on earth at the present day. At first sight he seems to be just a poor little scrubby underpaid man, groping blindly amid the mazes of the ultra-microscopic, engaging in bitter and lifelong quarrels over the nephridia of flatworms, waking perhaps one morning to find that someone whose name he has never heard has demolished by a few crucial experiments the work which he had hoped would render him immortal.

I remember vividly my student days, spending hours at the light microscope, turning endlessly the micrometric screw, and gazing at the blurred boundary which concealed the mysterious ground substance where the secret mechanisms of cell life might be found.

The foundations of population genetics were laid chiefly by mathematical deduction from basic premises contained in the works of Mendel and Morgan and their followers. Haldane, Wright, and Fisher are the pioneers of population genetics whose main research equipment was paper and ink rather than microscopes, experimental fields, Drosophila bottles, or mouse cages. Theirs is theoretical biology at its best, and it has provided a guiding light for rigorous quantitative experimentation and observation.

The history of the knowledge of the phenomena of life and of the organized world can be divided into two main periods. For a long time anatomy, and particularly the anatomy of the human body, was the a and ? of scientific knowledge. Further progress only became possible with the discovery of the microscope. A long time had yet to pass until through Schwann the cell was established as the final biological unit. It would mean bringing coals to Newcastle were I to describe here the immeasurable progress which biology in all its branches owes to the introduction of this concept of the cell. For this concept is the axis around which the whole of the modem science of life revolves.

The human mind prefers something which it can recognize to something for which it has no name, and, whereas thousands of persons carry field glasses to bring horses, ships, or steeples close to them, only a few carry even the simplest pocket microscope. Yet a small microscope will reveal wonders a thousand times more thrilling than anything which Alice saw behind the looking-glass.

The Microbe is so very small,
You cannot make him out at all.
But many sanguine people hope
To see him down a microscope.
His jointed tongue that lies beneath
A hundred curious rows of teeth;
His seven tufted tails with lots
Of lovely pink and purple spots
On each of which a pattern stands,
Composed of forty separate bands;
His eyebrows of a tender green;
All these have never yet been seen
But Scientists, who ought to know,
Assure us they must be so ...
Oh! let us never, never doubt
What nobody is sure about!

These motions were such as to satisfy me, after frequently repeated observation, that they arose neither from currents in the fluid, nor from its gradual evaporation, but belonged to the particle itself.
Summary of Brownian motion.

Until 1930 or thereabout biologists [using microscopes], in the situation of Astronomers and Astrophysicists, were permitted to see the objects of their interest, but not to touch them; the cell was as distant from us, as the stars and galaxies were from them.

[Microscopic] evidence cannot be presented ad populum. What is seen with the microscope depends not only upon the instrument and the rock-section, but also upon the brain behind the eye of the observer. Each of us looks at a section with the accumulated experience of his past study. Hence the veteran cannot make the novice see with his eyes; so that what carries conviction to the one may make no appeal to the other. This fact does not always seem to be sufficiently recognized by geologists at large.