[In reply to a question about how he got his expertise:]
By studying the masters and not their pupils.

[Recalling Professor Ira Remsen's remarks (1895) to a group of his graduate students about to go out with their degrees into the world beyond the university:]
He talked to us for an hour on what was ahead of us; cautioned us against giving up the desire to push ahead by continued study and work. He warned us against allowing our present accomplishments to be the high spot in our lives. He urged us not to wait for a brilliant idea before beginning independent research, and emphasized the fact the Lavoisier's first contribution to chemistry was the analysis of a sample of gypsum. He told u that the fields in which the great masters had worked were still fruitful; the ground had only been scratched and the gleaner could be sure of ample reward.

A man ceases to be a beginner in any given science and becomes a master in that science when he has learned that ... he is going to be a beginner all his life.

As pilgrimages to the shrines of saints draw thousands of English Catholics to the Continent, there may be some persons in the British Islands sufficiently in love with science, not only to revere the memory of its founders, but to wish for a description of the locality and birth-place of a great master of knowledge—John Dalton—who did more for the world's civilisation than all the reputed saints in Christendom.

Bacon first taught the world the true method of the study of nature, and rescued science from that barbarism in which the followers of Aristotle, by a too servile imitation of their master.

Chemistry has the same quickening and suggestive influence upon the algebraist as a visit to the Royal Academy, or the old masters may be supposed to have on a Browning or a Tennyson. Indeed it seems to me that an exact homology exists between painting and poetry on the one hand and modem chemistry and modem algebra on the other. In poetry and algebra we have the pure idea elaborated and expressed through the vehicle of language, in painting and chemistry the idea enveloped in matter, depending in part on manual processes and the resources of art for its due manifestation.

Fire is the best of servants, but what a master!

I prefer the spagyric chemical physicians, for they do not consort with loafers or go about gorgeous in satins, silks and velvets, gold rings on their fingers, silver daggers hanging at their sides and white gloves on their hands, but they tend their work at the fire patiently day and night. They do not go promenading, but seek their recreation in the laboratory, wear plain learthern dress and aprons of hide upon which to wipe their hands, thrust their fingers amongst the coals, into dirt and rubbish and not into golden rings. They are sooty and dirty like the smiths and charcoal burners, and hence make little show, make not many words and gossip with their patients, do not highly praise their own remedies, for they well know that the work must praise the master, not the master praise his work. They well know that words and chatter do not help the sick nor cure them... Therefore they let such things alone and busy themselves with working with their fires and learning the steps of alchemy. These are distillation, solution, putrefaction, extraction, calcination, reverberation, sublimination, fixation, separation, reduction, coagulation, tinction, etc.

It is the old experience that a rude instrument in the hand of a master craftsman will achieve more than the finest tool wielded by the uninspired journeyman.

No man can thoroughly master more than one art or science.

Nobody knows more than a tiny fragment of science well enough to judge its validity and value at first hand. For the rest he has to rely on views accepted at second hand on the authority of a community of people accredited as scientists. But this accrediting depends in its turn on a complex organization. For each member of the community can judge at first hand only a small number of his fellow members, and yet eventually each is accredited by all. What happens is that each recognizes as scientists a number of others by whom he is recognized as such in return, and these relations form chains which transmit these mutual recognitions at second hand through the whole community. This is how each member becomes directly or indirectly accredited by all. The system extends into the past. Its members recognize the same set of persons as their masters and derive from this allegiance a common tradition, of which each carries on a particular strand.

Once early in the morning, at two or three in the morning, when the master was asleep, the books in the library began to quarrel with each other as to which was the king of the library. The dictionary contended quite angrily that he was the master of the library because without words there would be no communication at all. The book of science argued stridently that he was the master of the library for without science there would have been no printing press or any of the other wonders of the world. The book of poetry claimed that he was the king, the master of the library, because he gave surcease and calm to his master when he was troubled. The books of philosophy, the economic books, all put in their claims, and the clamor was great and the noise at its height when a small low voice was heard from an old brown book lying in the center of the table and the voice said, “The Lord is my shepherd, I shall not want.” And all of the noise and the clamor in the library ceased, and there was a hush in the library, for all of the books knew who the real master of the library was.

Reason must approach nature with the view, indeed, of receiving information from it, not, however, in the character of a pupil, who listens to all that his master chooses to tell him, but in that of a judge, who compels the witnesses to reply to those questions which he himself thinks fit to propose. To this single idea must the revolution be ascribed, by which, after groping in the dark for so many centuries, natural science was at length conducted into the path of certain progress.

Science can give us only the tools in the box, these mechanical miracles that it has already given us. But of what use to us are miraculous tools until we have mastered the humane, cultural use of them? We do not want to live in a world where the machine has mastered the man; we want to live in a world where man has mastered the machine.

The responsibility for maintaining the composition of the blood in respect to other constituents devolves largely upon the kidneys. It is no exaggeration to say that the composition of the blood is determined not by what the mouth ingests but by what the kidneys keep; they are the master chemists of our internal environment, which, so to speak, they synthesize in reverse. When, among other duties, they excrete the ashes of our body fires, or remove from the blood the infinite variety of foreign substances which are constantly being absorbed from our indiscriminate gastrointestinal tracts, these excretory operations are incidental to the major task of keeping our internal environment in an ideal, balanced state. Our glands, our muscles, our bones, our tendons, even our brains, are called upon to do only one kind of physiological work, while our kidneys are called upon to perform an innumerable variety of operations. Bones can break, muscles can atrophy, glands can loaf, even the brain can go to sleep, without immediately endangering our survival, but when the kidneys fail to manufacture the proper kind of blood neither bone, muscle, gland nor brain can carry on.

There's nothing situate under heaven's eye
But hath his bond in earth, in sea, in sky.
The beasts, the fishes, and the winged fowls
Are their males' subjects and at their controls.
Man, more divine, the master of all these,
Lord of the wide world and wild wat'ry seas,
Indu'd with intellectual sense and souls,
Of more pre-eminence than fish and fowls,
Are masters to their females, and their lords;
Then let your will attend on their accords.