It is well to observe the force and virtue and consequence of discoveries, and these are to be seen nowhere more conspicuously than in those three which were unknown to the ancients, and of which the origins, although recent, are obscure and inglorious; namely, printing, gunpowder, and the magnet. For these three have changed the whole face and state of things throughout the world; the first in literature, the second in warfare, the third in navigation; whence have followed innumerable changes, insomuch that no empire, no sect, no star seems to have exerted greater power and influence in human affairs than these mechanical discoveries ... . But if a man endeavour to establish and extend the power and dominion of the human race itself over the universe, his ambition (if ambition it can be called) is without doubt both a more wholesome thing and a more noble than the other two. Now the empire of man over things depends wholly on the arts and sciences. For we cannot command nature except by obeying her.