Clarke's First Law: When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong.

A first-rate laboratory is one in which mediocre scientists can produce outstanding work.

A physician's subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.

A tidy laboratory means a lazy chemist.

All the world is a laboratory to the inquiring mind.

At my urgent request the Curie laboratory, in which radium was discovered a short time ago, was shown to me. The Curies themselves were away travelling. It was a cross between a stable and a potato-cellar, and, if I had not seen the worktable with the chemical apparatus, I would have thought it a practical joke.
Wilhelm Ostwald on seeing the Curie's laboratory facilities.

Don't despise empiric truth. Lots of things work in practice for which the laboratory has never found proof.

I have seen many phases of life; I have moved in imperial circles, I have been a Minister of State; but if I had to live my life again, I would always remain in my laboratory, for the greatest joy of my life has been to accomplish original scientific work, and, next to that, to lecture to a set of intelligent students.

In a word, I consider hospitals only as the entrance to scientific medicine; they are the first field of observation which a physician enters; but the true sanctuary of medical science is a laboratory; only there can he seek explanations of life in the normal and pathological states by means of experimental analysis.

In physics, mathematics, and astronautics [elderly] means over thirty; in the other disciplines, senile decay is sometimes postponed to the forties. There are, of course, glorious exceptions; but as every researcher just out of college knows, scientists of over fifty are good for nothing but board meetings, and should at all costs be kept out of the laboratory!
Defining 'elderly scientist' as in Clarke's First Law.

Sometimes my courage fails me and I think I ought to stop working, live in the country and devote myself to gardening. But I am held by a thousand bonds, and I don't know when I shall be able to arrange things otherwise. Nor do I know whether, even by writing scientific books, I could live without the laboratory.

There is no short cut from chemical laboratory to clinic, except one that passes too close to the morgue.

There is only one thing worse than coming home from the lab to a sink full of dirty dishes, and that is not going to the lab at all!

Time... is an essential requirement for effective research. An investigator may be given a palace to live in, a perfect laboratory to work in, he may be surrounded by all the conveniences money can provide; but if his time is taken from him he will remain sterile.

When chemists have brought their knowledge out of their special laboratories into the laboratory of the world, where chemical combinations are and have been through all time going on in such vast proportions,—when physicists study the laws of moisture, of clouds and storms, in past periods as well as in the present,—when, in short, geologists and zoologists are chemists and physicists, and vice versa,—then we shall learn more of the changes the world has undergone than is possible now that they are separately studied.

You are urgently warned against allowing yourself to be influenced in any way by theories or by other preconceived notions in the observation of phenomena, the performance of analyses and other determinations.

You know, I am sorry for the poor fellows that haven't got labs to work in.

[Chemistry] laboratory work was my first challenge. ... I still carry the scars of my first discovery—that test-tubes are fragile.