After Gibbs, one the most distinguished [American scientists] was Langley, of the Smithsonian. … He had the physicist's heinous fault of professing to know nothing between flashes of intense perception. … Rigidly denying himself the amusement of philosophy, which consists chiefly in suggesting unintelligible answers to insoluble problems, and liked to wander past them in a courteous temper, even bowing to them distantly as though recognizing their existence, while doubting their respectibility.

Through the discovery of Buchner, Biology was relieved of another fragment of mysticism. The splitting up of sugar into CO₂ and alcohol is no more the effect of a 'vital principle' than the splitting up of cane sugar by invertase. The history of this problem is instructive, as it warns us against considering problems as beyond our reach because they have not yet found their solution.