'...no pleasure is comparable to the standing upon the vantage ground of truth … and to see the errors … in the vale below:' so always that this prospect be with pity, and not with swelling or pride.
Quoting an unnamed poet and adding a comment.

... an opportunity to allow the bees in one's bonnet to buzz even more noisily than usual.

Alike fantastic, if too new, or old;
Be not the first by whom the new are try'd,
Not yet the last to lay the old aside.

An important scientific innovation rarely makes its way by gradually winning over and converting its opponents. What does happen is that its opponents gradually die out, and that the growing generation is familiarized with the ideas from the beginning.

Around here, however, we don't look backwards for very long. We keep moving forward, opening up new doors, and doing new things, because we're curious and curiosity keeps leading us down new paths.

As the births of living creatures are ill-shapen, so are all innovations, which are the births of time.

I had an immense advantage over many others dealing with the problem inasmuch as I had no fixed ideas derived from long-established practice to control and bias my mind, and did not suffer from the general belief that whatever is, is right.

I think it perfectly just, that he who, from the love of experiment, quits an approved for an uncertain practice, should suffer the full penalty of Egyptian law against medical innovation; as I would consign to the pillory, the wretch, who out of regard to his character, that is, to his fees, should follow the routine, when, from constant experience he is sure that his patient will die under it, provided any, not inhuman, deviation would give his patient a chance.

I'd climb in the car as it went down the assembly line and introduce myself. Then I'd ask for ideas.
[How, as Ford manager of development for the Taurus car, he sought input from Ford production employees.]

I'm convinced that the best solutions are often the ones that are counterintuitive - that challenge conventional thinking - and end in breakthroughs. It is always easier to do things the same old way...why change? To fight this, keep your dissatisfaction index high and break with tradition. Don't be too quick to accept the way things are being done. Question whether there's a better way. Very often you will find that once you make this break from the usual way - and incidentally, this is probably the hardest thing to do—and start on a new track your horizon of new thoughts immediately broadens. New ideas flow in like water. Always keep your interests broad - don't let your mind be stunted by a limited view.

If mankind is to profit freely from the small and sporadic crop of the heroically gifted it produces, it will have to cultivate the delicate art of handling ideas. Psychology is now able to tell us with reasonable assurance that the most influential obstacle to freedom of thought and to new ideas is fear; and fear which can with inimitable art disguise itself as caution, or sanity, or reasoned skepticism, or on occasion even as courage.

If there is a regulation that says you have to do something—whether it be putting in seat belts, catalytic converters, clean air for coal plants, clean water—the first tack that the lawyers use, among others things, and that companies use, is that it's going to drive the electricity bill up, drive the cost of cars up, drive everything up. It repeatedly has been demonstrated that once the engineers start thinking about it, it's actually far less than the original estimates. We should remember that when we hear this again, because you will hear it again.

Innovations, free thinking is blowing like a storm; those that stand in front of it, ignorant scholars like you, false scientists, perverse conservatives, obstinate goats, resisting mules are being crushed under the weight of these innovations. You are nothing but ants standing in front of the giants; nothing but chicks trying to challenge roaring volcanoes!

It's a good thing to turn your mind upside down now and then, like an hour-glass, to let the particles run the other way.

It’s very dangerous to invent something in our times; ostentatious men of the other world, who are hostile to innovations, roam about angrily. To live in peace, one has to stay away from innovations and new ideas. Innovations, like trees, attract the most destructive lightnings to themselves.

New ideas seem like frightening ghosts to people at the beginning; they run away from them for a long time, but they get tired of it in the end!

Surely every medicine is an innovation, and he that will not apply new remedies must expect new evils for time is the greatest innovator.

The human mind treats a new idea the way the body treats a strange protein; it rejects it.

The principal goal of education is to create men who are capable of doing new things, not simply of repeating what other generations have done—men who are creative, inventive, and discovers. The second goal of education is to form minds which can be critical, can verify, and not accept everything they are offered.

The reason why new concepts in any branch of science are hard to grasp is always the same; contemporary scientists try to picture the new concept in terms of ideas which existed before.

The same society which receives the rewards of technology must, as a cooperating whole, take responsibility for control. To deal with these new problems will require a new conservation. We must not only protect the countryside and save it from destruction, we must restore what has been destroyed and salvage the beauty and charm of our cities. Our conservation must be not just the classic conservation of protection and development, but a creative conservation of restoration and innovation. Its concern is not with nature alone, but with the total relation between man and the world around him. Its object is not just man's welfare, but the dignity of man's spirit.

We were not the victims of ancestor worship. We had the benefits of a fresh start.
[Explaining why his company became a leader in the digital HDTV industry.]

Who never walks save where he see men's tracks makes no discoveries.

…it ought to be remembered that there is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success, than to take the lead in the introduction of a new order of things. Because the innovator has for enemies all those who have done well under the old conditions, and lukewarm defenders in those who may do well under the new.