A person by study must try to disengage the subject from useless matter, and to seize on points capable of improvement. ... When subjects are viewed through the mists of prejudice, useful truths may escape.

Arguably the greatest technological triumph of the century has been the public-health system, which is sophisticated preventive and investigative medicine organized around mostly low- and medium-tech equipment; ... fully half of us are alive today because of the improvements.

Chess is a unique cognitive nexus, a place where art and science come together in the human mind and are then refined and improved by experience.

Every improvement that is put upon the real estate is the result of an idea in somebody's head. The skyscraper is another idea; the railroad is another; the telephone and all those things are merely symbols which represent ideas. An andiron, a wash-tub, is the result of an idea that did not exist before.

Frequently, I have been asked if an experiment I have planned is pure or applied science; to me it is more important to know if the experiment will yield new and probably enduring knowledge about nature. If it is likely to yield such knowledge, it is, in my opinion, good fundamental research; and this is more important than whether the motivation is purely aesthetic satisfaction on the part of the experimenter on the one hand or the improvement of the stability of a high-power transistor on the other.

I had gone on a walk on a fine Sabbath afternoon. I had entered the Green [of Glasgow] by the gate at the foot of Charlotte Street—had passed the old washing-house. I was thinking upon the engine at the time, and had gone as far as the herd's house, when the idea came into my mind that as steam was an elastic body it would rush into a vacuum, and if a communication were made between the cylinder and an exhausted vessel it would rush into it, and might be there condensed without cooling the cylinder. I then saw that I must get rid of the condensed steam and injection water if I used a jet, as in Newcomen's engine. Two ways of doing this occurred to me. First, the water might be run off by a descending pipe, if an outlet could be got at the depth of 35 or 36 feet, and any air might be extracted by a small pump. The second was to make the pump large enough to extract both water and air. ... I had not walked further than the Golf-house when the whole thing was arranged in my mind.
[In Robert Hart's words, a recollection of the description of Watt's moment of inspiration, in May 1765, for improving Thomas Newcomen's steam engine.]

I have no patience with attempts to identify science with measurement, which is but one of its tools, or with any definition of the scientist which would exclude a Darwin, a Pasteur or a Kekulé. The scientist is a practical man and his are practical aims. He does not seek the ultimate but the proximate. He does not speak of the last analysis but rather of the next approximation. His are not those beautiful structures so delicately designed that a single flaw may cause the collapse of the whole. The scientist builds slowly and with a gross but solid kind of masonry. If dissatisfied with any of his work, even if it be near the very foundations, he can replace that part without damage to the remainder. On the whole, he is satisfied with his work, for while science may never be wholly right it certainly is never wholly wrong; and it seems to be improving from decade to decade.

If the Weismann idea triumphs, it will be in a sense a triumph of fatalism; for, according to it, while we may indefinitely improve the forces of our education and surroundings, and this civilizing nurture will improve the individuals of each generation, its actual effects will not be cumulative as regards the race itself, but only as regards the environment of the race; each new generation must start de novo, receiving no increment of the moral and intellectual advance made during the lifetime of its predecessors. It would follow that one deep, almost instinctive motive for a higher life would be removed if the race were only superficially benefited by its nurture, and the only possible channel of actual improvement were in the selection of the fittest chains of race plasma.

If we lived on a planet where nothing ever changed, there would be little to do. There would be nothing to figure out. There would be no impetus for science. And if we lived in an unpredictable world, where things changed in random or very complex ways, we would not be able to figure things out. But we live in an in-between universe, where things change, but according to patterns, rules, or as we call them, laws of nature. If I throw a stick up in the air, it always falls down. If the sun sets in the west, it always rises again the next morning in the east. And so it becomes possible to figure things out. We can do science, and with it we can improve our lives.

Increased knowledge of heredity means increased power of control over the living thing, and as we come to understand more and more the architecture of the plant or animal we realize what can and what cannot be done towards modification or improvement.

Indians walk softly and hurt the landscape hardly more than the birds and squirrels, and their brush and bark huts last hardly longer than those of wood rats, while their more enduring monuments, excepting those wrought on the forests by the fires they made to improve their hunting grounds, vanish in a few centuries.

It be urged that the wild and uncultivated tree, hitherto yielding sour and bitter fruit only, can never be made to yield better; yet we know that the grafting art implants a new tree on the savage stock, producing what is most estimable in kind and degree. Education, in like manner, engrafts a new man on the native stock, and improves what in his nature was vicious and perverse into qualities of virtue and social worth.

It is not, indeed, strange that the Greeks and Romans should not have carried ... any ... experimental science, so far as it has been carried in our time; for the experimental sciences are generally in a state of progression. They were better understood in the seventeenth century than in the sixteenth, and in the eighteenth century than in the seventeenth. But this constant improvement, this natural growth of knowledge, will not altogether account for the immense superiority of the modern writers. The difference is a difference not in degree, but of kind. It is not merely that new principles have been discovered, but that new faculties seem to be exerted. It is not that at one time the human intellect should have made but small progress, and at another time have advanced far; but that at one time it should have been stationary, and at another time constantly proceeding. In taste and imagination, in the graces of style, in the arts of persuasion, in the magnificence of public works, the ancients were at least our equals. They reasoned as justly as ourselves on subjects which required pure demonstration.

Man is not the only animal who labors; but he is the only one who improves his workmanship.

My belief (is) that one should take a minimum of care and preparation over first experiments. If they are unsuccessful one is not then discouraged since many possible reasons for failure can be thought of, and improvements can be made. Much can often be learned by the repetition under different conditions, even if the desired result is not obtained. If every conceivable precaution is taken at first, one is often too discouraged to proceed at all.

My scientific work is motivated by an irresistible longing to understand the secrets of nature and by no other feeling. My love for justice and striving to contribute towards the improvement of human conditions are quite independent from my scientific interests.

Progress, far from consisting in change, depends on retentiveness. When change is absolute there remains no being to improve and no direction is set for possible improvement: and when experience is not retained, as among savages, infancy is perpetual. Those who cannot remember the past are condemned to repeat it.

Science is best defined as a careful, disciplined, logical search for knowledge about any and all aspects of the universe, obtained by examination of the best available evidence and always subject to correction and improvement upon discovery of better evidence. What's left is magic. And it doesn't work.

The business of their weekly Meetings shall be, To order, take account, consider, and discourse of Philosophical Experiments, and Observations: to read, hear, and discourse upon Letters, Reports, and other Papers containing Philosophical matters, as also to view, and discourse upon the productions and rarities of Nature, and Art: and to consider what to deduce from them, or how they may be improv'd for use, or discovery.

The Fundamental Regulator Paradox ... The task of a regulator is to eliminate variation, but this variation is the ultimate source of information about the quality of its work. Therefore, the better the job a regulator does the less information it gets about how to improve.

The more important fundamental laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote. Nevertheless, it has been found that there are apparent exceptions to most of these laws, and this is particularly true when the observations are pushed to a limit, i.e., whenever the circumstances of experiment are such that extreme cases can be examined. Such examination almost surely leads, not to the overthrow of the law, but to the discovery of other facts and laws whose action produces the apparent exceptions. As instances of such discoveries, which are in most cases due to the increasing order of accuracy made possible by improvements in measuring instruments, may be mentioned: first, the departure of actual gases from the simple laws of the so-called perfect gas, one of the practical results being the liquefaction of air and all known gases; second, the discovery of the velocity of light by astronomical means, depending on the accuracy of telescopes and of astronomical clocks; third, the determination of distances of stars and the orbits of double stars, which depend on measurements of the order of accuracy of one-tenth of a second-an angle which may be represented as that which a pin's head subtends at a distance of a mile. But perhaps the most striking of such instances are the discovery of a new planet or observations of the small irregularities noticed by Leverrier in the motions of the planet Uranus, and the more recent brilliant discovery by Lord Rayleigh of a new element in the atmosphere through the minute but unexplained anomalies found in weighing a given volume of nitrogen. Many other instances might be cited, but these will suffice to justify the statement that “our future discoveries must be looked for in the sixth place of decimals.”

Theories cannot claim to be indestructible. They are only the plough which the ploughman uses to draw his furrow and which he has every right to discard for another one, of improved design, after the harvest. To be this ploughman, to see my labours result in the furtherance of scientific progress, was the height of my ambition, and now the Swedish Academy of Sciences has come, at this harvest, to add the most brilliant of crowns.

This example illustrates the differences in the effects which may be produced by research in pure or applied science. A research on the lines of applied science would doubtless have led to improvement and development of the older methods—the research in pure science has given us an entirely new and much more powerful method. In fact, research in applied science leads to reforms, research in pure science leads to revolutions, and revolutions, whether political or industrial, are exceedingly profitable things if you are on the winning side.

Thus died Negro Tom [Thomas Fuller], this untaught arithmetician, this untutored scholar. Had his opportunities of improvement been equal to those of thousands of his fellow-men, neither the Royal Society of London, the Academy of Science at Paris, nor even a Newton himself need have been ashamed to acknowledge him a brother in science.
[Thomas Fuller (1710-1790), although enslaved from Africa at age 14, was an arithmetical prodigy. He was known as the Virginia Calculator because of his exceptional ability with arithmetic calculations. His intellectual accomplishments were related by Dr. Benjamin Rush in a letter read to the Pennsylvania Society for the Abolition of Slavery.]

Until now, physical theories have been regarded as merely models with approximately describe the reality of nature. As the models improve, so the fit between theory and reality gets closer. Some physicists are now claiming that supergravity is the reality, that the model and the real world are in mathematically perfect accord.

We are living now, not in the delicious intoxication induced by the early successes of science, but in a rather grisly morning-after, when it has become apparent that what triumphant science has done hitherto is to improve the means for achieving unimproved or actually deteriorated ends.

Whereas there is nothing more necessary for promoting the improvement of Philosophical Matters, than the communicating to such, as apply their Studies and Endeavours that way, such things as are discovered or put in practice by others; it is therefore thought fit to employ the Press, as the most proper way to gratifie those, whose engagement in such Studies, and delight in the advancement of Learning and profitable Discoveries, doth entitle them to the knowledge of what this Kingdom, or other parts of the World, do, from time to time, afford as well of the progress of the Studies, Labours, and attempts of the Curious and learned in things of this kind, as of their compleat Discoveries and performances: To the end, that such Productions being clearly and truly communicated, desires after solid and usefull knowledge may be further entertained, ingenious Endeavours and Undertakings cherished, and those, addicted to and conversant in such matters, may be invited and encouraged to search, try, and find out new things, impart their knowledge to one another, and contribute what they can to the Grand design of improving Natural knowledge, and perfecting all Philosophical Arts, and Sciences. All for the Glory of God, the Honour and Advantage of these Kingdoms, and the Universal Good of Mankind.

Without an acquaintance with chemistry, the statesman must remain a stranger to the true vital interests of the state, to the means of its organic development and improvement; ... The highest economic or material interests of a country, the increased and more profitable production of food for man and animals, ... are most closely linked with the advancement and diffusion of the natural sciences, especially of chemistry.

[Modern science] passed through a long period of uncertainty and inconclusive experiment, but as the instrumental aids to research improved, and the results of observation accumulated, phantoms of the imagination were exorcised, idols of the cave were shattered, trustworthy materials were obtained for logical treatment, and hypotheses by long and careful trial were converted into theories.