A common fallacy in much of the adverse criticism to which science is subjected today is that it claims certainty, infallibility and complete emotional objectivity. It would be more nearly true to say that it is based upon wonder, adventure and hope.

Despair is better treated with hope, not dope.

For the essence of science, I would suggest, is simply the refusal to believe on the basis of hope.

He who has health has hope; and he who has hope has everything.

Hope is a good breakfast, but it is a bad supper.

Hopes are always accompanied by fears, and, in scientific research, the fears are liable to become dominant.
At age 67.

I cannot anyhow be contented to view this wonderful universe, and especially the nature of man, and to conclude that everything is the result of brute force. I am inclined to look at everything as resulting from designed laws, with the details, whether good or bad, left to the working out of what we call chance. Not that this notion at all satisfies me. I feel most deeply that the whole subject is too profound for the human intellect. A dog might as well speculate on the mind of Newton. Let each man hope and believe what he can.

I think that support of this [stem cell] research is a pro-life pro-family position. This research holds out hope for more than 100 million Americans.

PHYSICIAN, n. One upon whom we set our hopes when ill and our dogs when well.

The only hope [of science] ... is in genuine induction.

There is another ground of hope that must not be omitted. Let men but think over their infinite expenditure of understanding, time, and means on matters and pursuits of far less use and value; whereof, if but a small part were directed to sound and solid studies, there is no difficulty that might not be overcome.

There is romance, the genuine glinting stuff, in typewriters, and not merely in their development from clumsy giants into agile dwarfs, but in the history of their manufacture, which is filled with raids, battles, lonely pioneers, great gambles, hope, fear, despair, triumph. If some of our novels could be written by the typewriters instead of on them, how much better they would be.

[Magic] enables man to carry out with confidence his important tasks, to maintain his poise and his mental integrity in fits of anger, in the throes of hate, of unrequited love, of despair and anxiety. The function of magic is to ritualize man's optimism, to enhance his faith in the victory of hope over fear. Magic expresses the greater value for man of confidence over doubt, of steadfastness over vacillation, of optimism over pessimism.

[Man] ... his origin, his growth, his hopes and fears, his loves and his beliefs are but the outcome of accidental collocations of atoms; that no fire, no heroism, no intensity of thought and feeling can preserve an individual life beyond the grave; that all the labour of the ages, all the devotion, all the inspiration, all the noonday brightness of human genius are destined to extinction in the vast death of the solar system, and that the whole temple of Man's achievement must inevitably be buried beneath the debris of a universe in ruins...