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Heredity Quotes (43 quotes)

A cell has a history; its structure is inherited, it grows, divides, and, as in the embryo of higher animals, the products of division differentiate on complex lines. Living cells, moreover, transmit all that is involved in their complex heredity. I am far from maintaining that these fundamental properties may not depend upon organisation at levels above any chemical level; to understand them may even call for different methods of thought; I do not pretend to know. But if there be a hierarchy of levels we must recognise each one, and the physical and chemical level which, I would again say, may be the level of self-maintenance, must always have a place in any ultimate complete description.
'Some Aspects of Biochemistry', The Irish Journal of Medical Science (1932), 79, 346.
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A moment's consideration of this case shows what a really great advance in the theory and practise of breeding has been obtained through the discovery of Mendel's law. What a puzzle this case would have presented to the biologist ten years ago! Agouti crossed with chocolate gives in the second filial generation (not in the first) four varieties, viz., agouti, chocolate, black and cinnamon. We could only have shaken our heads and looked wise (or skeptical).
Then we had no explanation to offer for such occurrences other than the 'instability of color characters under domestication,' the 'effects of inbreeding,' 'maternal impressions.' Serious consideration would have been given to the proximity of cages containing both black and cinnamon-agouti mice.
Now we have a simple, rational explanation, which anyone can put to the test. We are able to predict the production of new varieties, and to produce them.
We must not, of course, in our exuberance, conclude that the powers of the hybridizer know no limits. The result under consideration consists, after all, only in the making of new combinations of unit characters, but it is much to know that these units exist and that all conceivable combinations of them are ordinarily capable of production. This valuable knowledge we owe to the discoverer and to the rediscoverers of Mendel's law.
'New Colour Variety of the Guinea Pig', Science, 1908, 28, 250-252.
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Blood mixture and the result drop in the racial level is the sole cause of the dying out of old cultures; for men do not perish as a result of lost wars, but by the loss of that force of resistance which is continued only in pure blood. All who are not of good race in this world are chaff.
Mein Kampf (1925-26), American Edition (1943), 296. In William Lawrence Shirer, The Rise and Fall of the Third Reich (1990), 88.
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Characteristics cling to families.
Hereditary Genius (1869), v.

Contrary to popular parlance, Darwin didn't discover evolution. He uncovered one (most would say the) essential mechanism by which it operates: natural selection. Even then, his brainstorm was incomplete until the Modern Synthesis of the early/mid-20th century when (among other things) the complementary role of genetic heredity was fully realized. Thousands upon thousands of studies have followed, providing millions of data points that support this understanding of how life on Earth has come to be as it is.
In online article, 'The Day That Botany Took on Bobby Jindal by Just Being Itself', Huffington Post (5 Aug 2013).
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Ever so often in the history of human endeavour, there comes a breakthrough that takes humankind across a frontier into a new era. ... today's announcement is such a breakthrough, a breakthrough that opens the way for massive advancement in the treatment of cancer and hereditary diseases. And that is only the beginning.
From White House Announcement of the Completion of the First Survey of the Entire Human Genome Project, broadcast on the day of the publication of the first draft of the human genome. Quoted in transcript on the National Archives, Clinton White House web site, 'Text of Remarks on the Completion of the First Survey of the Entire Human Genome Project' (26 Jun 2000).
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For it is not cell nuclei, not even individual chromosomes, but certain parts of certain chromosomes from certain cells that must be isolated and collected in enormous quantities for analysis; that would be the precondition for placing the chemist in such a position as would allow him to analyse [the hereditary material] more minutely than [can] the morphologists ... For the morphology of the nucleus has reference at the very least to the gearing of the clock, but at best the chemistry of the nucleus refers only to the metal from which the gears are formed.
Ergebnisse über die Konstitution der chromatischen Substam des Zellkems (1904), 123. Translated in Robert Olby, The Path to the Double Helix: The Discovery of DNA (1994), xx.
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From the point of view of the pure morphologist the recapitulation theory is an instrument of research enabling him to reconstruct probable lines of descent; from the standpoint of the student of development and heredity the fact of recapitulation is a difficult problem whose solution would perhaps give the key to a true understanding of the real nature of heredity.
Form and Function: A Contribution to the History of Animal Morphology (1916), 312-3.
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Heredity is the general expression of the periodicity of organic life. All generations belong to a continuous succession of waves, in which every single one resembles its predecessors and its followers.
In 'On the Principles of Animal Morphology', Proceedings of the Royal Society of Edinburgh (1888), 15, 295. Original as Letter to Mr John Murray, communicated to the Society by Professor Sir William Turner. Page given as in collected volume published 1889.
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Heredity is to-day the central problem of biology. This problem may be approached from many sides—that of the breeder, the experimenter, the statistician, the physiologist, the embryologist, the cytologist—but the mechanism of heredity can be studied best by the investigation of the germ cells and their development.
'The Mechanism of Heredity', Science, 1905, 27, 89-90.
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Heredity proposes and development disposes.
'Postscript: D' Arcy Thompson and Growth and Form'. From Ruth D' Arcy Thompson, D' Arcy Wentworth Thompson: The Scholar Naturalist 1860-1948 (1958), 225.
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Heredity, to our understanding is not capable of giving to this illness (paraphilia) its characteristic form ... Heredity invents nothing, creates nothing anew; it has no imagination.
Études de psychologie expérimentale: Le fétichisme dans l’amour (1888), 42.

I am the family face:
Flesh perishes, I live on,
Projecting trait and trace
Through time to times anon,
And leaping from place to place
Over oblivion.
'Heredity'. In James Gibson (ed.), The Complete Poems of Thomas Hardy (1976), 434.

I may finally call attention to the probability that the association of paternal and maternal chromosomes in pairs and their subsequent separation during the reducing division as indicated above may constitute the physical basis of the Mendelian law of heredity.
'On the Morphology of the Chromosome Group in Brachystola Magna', Biological Bulletin (1902), 4, 39.
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I should be the last to discard the law of organic heredity ... but the single word “heredity” cannot dispense science from the duty of making every possible inquiry into the mechanism of organic growth and of organic formation. To think that heredity will build organic beings without mechanical means is a piece of unscientific mysticism.
In 'On the Principles of Animal Morphology', Proceedings of the Royal Society of Edinburgh (1888), 15, 294-295. Original as Letter to Mr John Murray, communicated to the Society by Professor Sir William Turner. Page given as in collected volume published 1889.
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If a given scientist had not made a given discovery, someone else would have done so a little later. Johann Mendel dies unknown after having discovered the laws of heredity: thirty-five years later, three men rediscover them. But the book that is not written will never be written. The premature death of a great scientist delays humanity; that of a great writer deprives it.
Pensées d'un Biologiste (1939). Translated in The Substance of Man (1962), 89.
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If the Weismann idea triumphs, it will be in a sense a triumph of fatalism; for, according to it, while we may indefinitely improve the forces of our education and surroundings, and this civilizing nurture will improve the individuals of each generation, its actual effects will not be cumulative as regards the race itself, but only as regards the environment of the race; each new generation must start de novo, receiving no increment of the moral and intellectual advance made during the lifetime of its predecessors. It would follow that one deep, almost instinctive motive for a higher life would be removed if the race were only superficially benefited by its nurture, and the only possible channel of actual improvement were in the selection of the fittest chains of race plasma.
'The Present Problem of Heredity', The Atlantic Monthly (1891), 57, 363.
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If we thus go very far back to the source of the Mammalian type of organisation; it is extremely improbable that any of [his relatives shall likewise] the successors of his relations now exist,—In same manner, if we take [a man from] any large family of 12 brothers & sisters [in a state which does not increase] it will be chances against anyone [of them] having progeny living ten thousand years hence; because at present day many are relatives so that tracing back the [descen] fathers would be reduced to small percentage.—& [in] therefore the chances are excessively great against, any two of the 12, having progeny, after that distant period.
P. H. Barrett et al. (eds.), Charles Darwin's Notebooks, 1836-1844: Geology, Transmutation of the Species and Metaphysical Enquiries (1987), Notebook B, 40-1.

In the course of individual development, inherited characters appear, in general, earlier than adaptive ones, and the earlier a certain character appears in ontogeny, the further back must lie in time when it was acquired by its ancestors.
Allgemeine Entwickelungsgeschichte der Organismen (1866), Vol. 2, 298. Trans. Stephen Jay Gould, Ontogeny and Phylogeny (1977), 81.
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Increased knowledge of heredity means increased power of control over the living thing, and as we come to understand more and more the architecture of the plant or animal we realize what can and what cannot be done towards modification or improvement.
Reginald C. Punnett, in article 'Mendelism', from Hugh Chisholm (ed.) The Encyclopædia Britannica (1911), Vol. 18, 120.
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It is clear that in maize, seemingly blending is really segregating inheritance, but with entire absence of dominance, and it seems probably that the same will be found to be true among rabbits and other mammals; failure to observe it hitherto is probably due to the fact that the factors concerned are numerous. For the greater the number of factors concerned, the more nearly will the result obtained approximate a complete and permanent blend. As the number of factors approaches infinity, the result will become identical with a permanent blend.
Heredity: In Relation to Evolution and Animal Breeding (1911), 138-9.
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No other explanation of living forms is allowed than heredity, and any which is founded on another basis must be rejected. The present fashion requires that even the smallest and most indifferent inquiry must be dressed in phylogenetic costume, and whilst in former centuries authors professed to read in every natural detail some intention of the creator mundi, modern scientists have the aspiration to pick out from every occasional observation a fragment of the ancestral history of the living world.
'On the Principles of Animal Morphology', Proceedings of the Royal Society of Edinburgh (2 Apr 1888), 15, 294. Original as Letter to Mr John Murray, communicated to the Society by Professor Sir William Turner. Page given as in collected volume published 1889.
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Now it is a well-known principle of zoological evolution that an isolated region, if large and sufficiently varied in its topography, soil, climate and vegetation, will give rise to a diversified fauna according to the law of adaptive radiation from primitive and central types. Branches will spring off in all directions to take advantage of every possible opportunity of securing food. The modifications which animals undergo in this adaptive radiation are largely of mechanical nature, they are limited in number and kind by hereditary, stirp or germinal influences, and thus result in the independent evolution of similar types in widely-separated regions under the law of parallelism or homoplasy. This law causes the independent origin not only of similar genera but of similar families and even of our similar orders. Nature thus repeats herself upon a vast scale, but the similarity is never complete and exact.
'The Geological and Faunal Relations of Europe and America during the Tertiary Period and the Theory of the Successive Invasions of an African Fauna', Science (1900), 11, 563-64.
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Owing to the imperfection of language the offspring is termed a new animal, but it is in truth a branch or elongation of the parent; since a part of the embryon-animal is, or was, a part of the parent; and therefore in strict language it cannot be said to be entirely new at the time of its production; and therefore it may retain some of the habits of the parent-system. (1794)
Zoonomia, Or, The Laws of Organic Life, in three parts (1803), Vol. 1, 395.
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Religion shows a pattern of heredity which I think is similar to genetic heredity. ... There are hundreds of different religious sects, and every religious person is loyal to just one of these. ... The overwhelming majority just happen to choose the one their parents belonged to. Not the sect that has the best evidence in its favour, the best miracles, the best moral code, the best cathedral, the best stained-glass, the best music when it comes to choosing from the smorgasbord of available religions, their potential virtues seem to count for nothing compared to the matter of heredity.
From edited version of a speech, at the Edinburgh International Science Festival (15 Apr 1992), as reprinted from the Independent newspaper in Alec Fisher, The Logic of Real Arguments (2004), 82-83.
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That the fundamental aspects of heredity should have turned out to be so extraordinarily simple supports us in the hope that nature may, after all, be entirely approachable. Her much-advertised inscrutability has once more been found to be an illusion due to our ignorance. This is encouraging, for, if the world in which we live were as complicated as some of our friends would have us believe we might well despair that biology could ever become an exact science.
The Physical Basis of Heredity (1919), 15.
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The admirable perfection of the adaptations of organisms and of their parts to the functions they perform has detracted attention from the fact that adaptedness does not consist of perfect fit, but capacity to fit or to adapt in a variety of ways: only in this sense is adaptedness a guarantee of further survival and evolutionary progress, for too perfect a fit is fatal to the species if not to the individual. This, I think, sets phylogeny and ontogeny in the correct perspective. It is the genotype which bears the marks of past experience of the species and defines the range of possible fits. What fit is actually chosen, what phenotype is actually evolved, is determined by the ever renewed individual history.
'The Interplay of Heredity and Environment in the Synthesis of Respiratory Enzymes in Yeast', The Harvey Lectures: Delivered under the auspices of The Harvey Society of New York 1950-1951, 1951, 156, 45-6.
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The advances of biology during the past 20 years have been breathtaking, particularly in cracking the mystery of heredity. Nevertheless, the greatest and most difficult problems still lie ahead. The discoveries of the 1970‘s about the chemical roots of memory in nerve cells or the basis of learning, about the complex behavior of man and animals, the nature of growth, development, disease and aging will be at least as fundamental and spectacular as those of the recent past.
As quoted in 'H. Bentley Glass', New York Times (12 Jan 1970), 96.
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The argument advanced by the supporters of the theory of hereditary transmission does not furnish a satisfactory explanation of the cause of the inequalities and diversities of the universe.
Vedanta Philosophy: Five Lectures on Reincarnation (1902), 41.
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The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
In Jacques Monod and Austryn Wainhouse (trans.), Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology (1971), 104.
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The genes are the atoms of heredity.
'Genetic Fine Structure', Lecture delivered 15 September 1960. Quoted in The Harvey Lectures, Series 56 (1961), 1.
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The genotypic constitution of a gamete or a zygote may be parallelized with a complicated chemico-physical structure. This reacts exclusively in consequence of its realized state, but not in consequence of the history of its creation. So it may be with the genotypical constitution of gametes and zygotes: its history is without influence upon its reactions, which are determined exclusively by its actual nature. The genotype-conception is thus an 'ahistoric' view of the reactions of living beings—of course only as far as true heredity is concerned. This view is an analog to the chemical view, as already pointed out; chemical compounds have no compromising ante-act, H2O is always H2O, and reacts always in the same manner, whatsoever may be the 'history' of its formation or the earlier states of its elements. I suggest that it is useful to emphasize this 'radical' ahistoric genotype-conception of heredity in its strict antagonism to the transmission—or phenotype-view.
'The Genotype Conception of Heredity', The American Naturalist (1911), 45, 129.
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The nucleic acids, as constituents of living organisms, are comparable In importance to proteins. There is evidence that they are Involved In the processes of cell division and growth, that they participate In the transmission of hereditary characters, and that they are important constituents of viruses. An understanding of the molecular structure of the nucleic acids should be of value In the effort to understand the fundamental phenomena of life.
[Co-author with American chemist, B. Corey (1897-1971)]
'A Proposed Structure for the Nucleic Acids', Proceedings of the National Academy of Sciences (1953), 39, 84.
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The ovary of an ancestress will contain not only her daughter, but also her granddaughter, her great-grand-daughter, and her great-great-granddaughter, and if it is once proved that an ovary can contain many generations, there is no absurdity in saying that it contains them all.
Attributed.

The philosophical implication of race-thinking is that by offering us the mystery of heredity as an explanation, it diverts our attention from the social and intellectual factors that make up personality.
Race(1937), 282.
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The process of natural selection has been summed up in the phrase “survival of the fittest.” This, however, tells only part of the story. “Survival of the existing” in many cases covers more of the truth. For in hosts of cases the survival of characters rests not on any special usefulness or fitness, but on the fact that individuals possessing these characters have inhabited or invaded a certain area. The principle of utility explains survivals among competing structures. It rarely accounts for qualities associated with geographic distribution.
The nature of animals which first colonize a district must determine what the future fauna will be. From their specific characters, which are neither useful nor harmful, will be derived for the most part the specific characters of their successors.
It is not essential to the meadow lark that he should have a black blotch on the breast or the outer tail-feather white. Yet all meadow larks have these characters just as all shore larks have the tiny plume behind the ear. Those characters of the parent stock, which may be harmful in the new relations, will be eliminated by natural selection. Those especially helpful will be intensified and modified, but the great body of characters, the marks by which we know the species, will be neither helpful nor hurtful. These will be meaningless streaks and spots, variations in size of parts, peculiar relations of scales or hair or feathers, little matters which can neither help nor hurt, but which have all the persistence heredity can give.
Foot-notes to Evolution. A Series of Popular Addresses on the Evolution of Life (1898), 218.
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The processes concerned in simple descent are those of Family Variability and Reversion. It is well to define these words clearly. By family variability is meant the departure of the children of the same or similarly descended families from the ideal mean type of all of them. Reversion is the tendency of that ideal mean type to depart from the parent type, 'reverting' towards what may be roughly and perhaps fairly described as the average ancestral type. If family variability had been the only process in simple descent, the dispersion of the race would indefinitely increase with the number of the generations, but reversion checks this increase, and brings it to a standstill.
Typical Laws of Heredity (1877), 513.

This missing science of heredity, this unworked mine of knowledge on the borderland of biology and anthropology, which for all practical purposes is as unworked now as it was in the days of Plato, is, in simple truth, ten times more important to humanity than all the chemistry and physics, all the technical and indsutrial science that ever has been or ever will be discovered.
Mankind in the Making (1903), 72.
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We do not know of any enzymes or other chemical defined organic substances having specifically acting auto-catalytic properties such as to enable them to construct replicas of themselves. Neither was there a general principle known that would result in pattern-copying; if there were, the basis of life would be easier to come by. Moreover, there was no evidence to show that the enzymes were not products of hereditary determiners or genes, rather than these genes themselves, and they might even be products removed by several or many steps from the genes, just as many other known substances in the cell must be. However, the determiners or genes themselves must conduct, or at least guide, their own replication, so as to lead to the formation of genes just like themselves, in such wise that even their own mutations become .incorporated in the replicas. And this would probably take place by some kind of copying of pattern similar to that postulated by Troland for the enzymes, but requiring some distinctive chemical structure to make it possible. By virtue of this ability of theirs to replicate, these genes–or, if you prefer, genetic material–contained in the nuclear chromosomes and in whatever other portion of the cell manifests this property, such as the chloroplastids of plants, must form the basis of all the complexities of living matter that have arisen subsequent to their own appearance on the scene, in the whole course of biological evolution. That is, this genetic material must underlie all evolution based on mutation and selective multiplication.
'Genetic Nucleic Acid', Perspectives in Biology and Medicine (1961), 5, 6-7.
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We shall therefore take an appropriately correct view of the origin of our life, if we consider our own embryos to have sprung immediately from those embryos whence our parents were developed, and these from the embryos of their parents, and so on for ever. We should in this way look on the nature of mankind, and perhaps on that of the whole animated creation, as one Continuous System, ever pushing out new branches in all directions, that variously interlace, and that bud into separate lives at every point of interlacement.
'Hereditary Talent and Character', Macmillan's Magazine, 1865, 12, 322.
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When... the biologist is confronted with the fact that in the organism the parts are so adapted to each other as to give rise to a harmonious whole; and that the organisms are endowed with structures and instincts calculated to prolong their life and perpetuate their race, doubts as to the adequacy of a purely physiochemical viewpoint in biology may arise. The difficulties besetting the biologist in this problem have been rather increased than diminished by the discovery of Mendelian heredity, according to which each character is transmitted independently of any other character. Since the number of Mendelian characters in each organism is large, the possibility must be faced that the organism is merely a mosaic of independent hereditary characters. If this be the case the question arises: What moulds these independent characters into a harmonious whole? The vitalist settles this question by assuming the existence of a pre-established design for each organism and of a guiding 'force' or 'principle' which directs the working out of this design. Such assumptions remove the problem of accounting for the harmonious character of the organism from the field of physics or chemistry. The theory of natural selection invokes neither design nor purpose, but it is incomplete since it disregards the physiochemical constitution of living matter about which little was known until recently.
The Organism as a Whole: From a Physiochemical Viewpoint (1916), v-vi.
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Whereas, to borrow an illustration from mathematics, life was formerly an equation of, say, 100 unknown quantities, it is now one of 99 only, inasmuch as memory and heredity have been shown to be one and the same thing.
Samuel Butler, Henry Festing Jones (ed.), The Note-Books of Samuel Butler (1917), 57.
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[Other than fossils,] the most important of these other records of creation is, without doubt, ontogeny, that is, the history of the developmment of the organic individual (embryology and motamorphology). It briefly repeats in great and marked features the series of forms which the ancestors of the respective individuals have passed through from the beginning of their tribe. We have designated the palaeontological history of the development of the ancestors of a living form as the history of a tribe, or phylogeny, and we may therefore thus enunciate this exceedingly important biogenetic fundamental principle: “Ontogeny is a short and quick repetition, or recapitulation, of Phylogeny, determined by the laws of Inheritance and Adaptation.”
In Ernst Haeckel and E. Ray Lankester (trans.), The History of Creation (1876), Vol. 2, 33. Seen shortened to “Ontogeny recapitulates phylogeny.” This was Haeckel's (incorrect) answer to the vexing question of his time: what is the relationship between individual development (ontogeny) and the evolution of species and lineages (phylogeny)?
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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- 100 -
Sophie Germain
Gertrude Elion
Ernest Rutherford
James Chadwick
Marcel Proust
William Harvey
Johann Goethe
John Keynes
Carl Gauss
Paul Feyerabend
- 90 -
Antoine Lavoisier
Lise Meitner
Charles Babbage
Ibn Khaldun
Euclid
Ralph Emerson
Robert Bunsen
Frederick Banting
Andre Ampere
Winston Churchill
- 80 -
John Locke
Bronislaw Malinowski
Bible
Thomas Huxley
Alessandro Volta
Erwin Schrodinger
Wilhelm Roentgen
Louis Pasteur
Bertrand Russell
Jean Lamarck
- 70 -
Samuel Morse
John Wheeler
Nicolaus Copernicus
Robert Fulton
Pierre Laplace
Humphry Davy
Thomas Edison
Lord Kelvin
Theodore Roosevelt
Carolus Linnaeus
- 60 -
Francis Galton
Linus Pauling
Immanuel Kant
Martin Fischer
Robert Boyle
Karl Popper
Paul Dirac
Avicenna
James Watson
William Shakespeare
- 50 -
Stephen Hawking
Niels Bohr
Nikola Tesla
Rachel Carson
Max Planck
Henry Adams
Richard Dawkins
Werner Heisenberg
Alfred Wegener
John Dalton
- 40 -
Pierre Fermat
Edward Wilson
Johannes Kepler
Gustave Eiffel
Giordano Bruno
JJ Thomson
Thomas Kuhn
Leonardo DaVinci
Archimedes
David Hume
- 30 -
Andreas Vesalius
Rudolf Virchow
Richard Feynman
James Hutton
Alexander Fleming
Emile Durkheim
Benjamin Franklin
Robert Oppenheimer
Robert Hooke
Charles Kettering
- 20 -
Carl Sagan
James Maxwell
Marie Curie
Rene Descartes
Francis Crick
Hippocrates
Michael Faraday
Srinivasa Ramanujan
Francis Bacon
Galileo Galilei
- 10 -
Aristotle
John Watson
Rosalind Franklin
Michio Kaku
Isaac Asimov
Charles Darwin
Sigmund Freud
Albert Einstein
Florence Nightingale
Isaac Newton