Bernard: Oh, you're going to zap me with penicillin and pesticides. Spare me that and I'll spare you the bomb and aerosols. But don't confuse progress with perfectibility. A great poet is always timely. A great philosopher is an urgent need. There's no rush for Isaac Newton. We were quite happy with Aristotle's cosmos. Personally, I preferred it. Fifty-five crystal spheres geared to God's crankshaft is my idea of a satisfying universe. I can't think of anything more trivial than the speed of light. Quarks, quasars—big bangs, black holes—who [cares]? How did you people con us out of all that status? All that money? And why are you so pleased with yourselves?
Chloe: Are you against penicillin, Bernard?
Bernard: Don't feed the animals.

All great scientists have, in a certain sense, been great artists; the man with no imagination may collect facts, but he cannot make great discoveries.

Consider now the Milky Way. Here also we see an innumerable dust, only the grains of this dust are no longer atoms but stars; these grains also move with great velocities, they act at a distance one upon another, but this action is so slight at great distances that their trajectories are rectilineal; nevertheless, from time to time, two of them may come near enough together to be deviated from their course, like a comet that passed too close to Jupiter. In a word, in the eyes of a giant, to whom our Suns were what our atoms are to us, the Milky Way would only look like a bubble of gas.

Every work of science great enough to be well remembered for a few generations affords some exemplification of the defective state of the art of reasoning of the time when it was written; and each chief step in science has been a lesson in logic.

Great inventions are never, and great discoveries are seldom, the work of any one mind. Every great invention is really an aggregation of minor inventions, or the final step of a progression. It is not usually a creation, but a growth, as truly so as is the growth of the trees in the forest.

I can see him now at the blackboard, chalk in one hand and rubber in the other, writing rapidly and erasing recklessly, pausing every few minutes to face the class and comment earnestly, perhaps on the results of an elaborate calculation, perhaps on the greatness of the Creator, perhaps on the beauty and grandeur of Mathematics, always with a capital M. To him mathematics was not the handmaid of philosophy. It was not a humanly devised instrument of investigation, it was Philosophy itself, the divine revealer of TRUTH.

I long to speak out the intense inspiration that comes to me from the lives of strong women. They have made of their lives a great adventure.

I saw [Linus Pauling] as a brilliant lecturer and a man with a fantastic memory, and a great, great showman. I think he was the century’s greatest chemist. No doubt about it.

Is it a fact—or have I dreamt it—that, by means of electricity, the world of matter has become a great nerve, vibrating thousands of miles in a breathless point of time?

It would appear... that moral phenomena, when observed on a great scale, are found to resemble physical phenomena; and we thus arrive, in inquiries of this kind, at the fundamental principle, that the greater the number of individuals observed, the more do individual peculiarities, whether physical or moral, become effaced, and leave in a prominent point of view the general facts, by virtue of which society exists and is preserved.

Most people like to believe something is or is not true. Great scientists tolerate ambiguity very well. They believe the theory enough to go ahead; they doubt it enough to notice the errors and faults so they can step forward and create the new replacement theory. If you believe too much you'll never notice the flaws; if you doubt too much you won't get started. It requires a lovely balance.

The first [quality] to be named must always be the power of attention, of giving one's whole mind to the patient without the interposition of anything of oneself. It sounds simple but only the very greatest doctors ever fully attain it. ... The second thing to be striven for is intuition. This sounds an impossibility, for who can control that small quiet monitor? But intuition is only interference from experience stored and not actively recalled. ... The last aptitude I shall mention that must be attained by the good physician is that of handling the sick man's mind.

The scientist, if he is to be more than a plodding gatherer of bits of information, needs to exercise an active imagination. The scientists of the past whom we now recognize as great are those who were gifted with transcendental imaginative powers, and the part played by the imaginative faculty of his daily life is as least as important for the scientist as it is for the worker in any other field—much more important than for most. A good scientist thinks logically and accurately when conditions call for logical and accurate thinking—but so does any other good worker when he has a sufficient number of well-founded facts to serve as the basis for the accurate, logical induction of generalizations and the subsequent deduction of consequences.

The technologies which have had the most profound effects on human life are usually simple. A good example of a simple technology with profound historical consequences is hay. ... It was hay that allowed populations to grow and civilizations to flourish among the forests of Northern Europe. Hay moved the greatness of Rome to Paris and London, and later to Berlin and Moscow and New York.
[The year-round growth of green grass in the Mediterranean climate meant that hay was not needed by the Romans. North of the Alps, hay maintained horses and oxen and thus their motive power, and productivity.]

There are some men who are counted great because they represent the actuality of their own age, and mirror it as it is. Such an one was Voltaire, of whom it was epigrammatically said: 'he expressed everybody's thoughts better than anyone.' But there are other men who attain greatness because they embody the potentiality of their own day and magically reflect the future. They express the thoughts which will be everybody's two or three centuries after them. Such as one was Descartes.

To what part of electrical science are we not indebted to Faraday? He has increased our knowledge of the hidden and unknown to such an extent, that all subsequent writers are compelled so frequently to mention his name and quote his papers, that the very repetition becomes monotonous. [How] humiliating it may be to acknowledge so great a share of successful investigation to one man...

True greatness is when your name is like ampere, watt, and fourier—when it's spelled with a lower case letter.

We affirm the neutrality of Science ... Science is of no country. ... But if Science has no country, the scientist must keep in mind all that may work towards the glory of his country. In every great scientist will be found a great patriot.

We all felt the majesty of the body. In a very short period of time we had seen something that was bigger than each of us. A lot of people, even those who were not religious, were reverent and attributed the success to God. As we saw the artificial heart beat in Dr. Clark, the feeling was not aren't we great, but aren't we small.
[Comment after surgery for the world's first human implant of a total artificial heart in the chest of dentist Dr. Barney Clark ]

Worship the spirit of criticism. If reduced to itself it is not an awakener of ideas or a stimulant to great things, but, without it, everything is fallible; it always has the last word.

[Great scientists] are men of bold ideas, but highly critical of their own ideas: they try to find whether their ideas are right by trying first to find whether they are not perhaps wrong. They work with bold conjectures and severe attempts at refuting their own conjectures.