A game is on, at the other end of this infinite distance, and heads or tails will turn up. What will you wager? According to reason you cannot leave either; according to reason you cannot leave either undone... Yes, but wager you must; there is no option, you have embarked on it. So which will you have. Come. Since you must choose, let us see what concerns you least. You have two things to lose: truth and good, and two things to stake: your reason and your will, your knowledge and your happiness. And your nature has two things to shun: error and misery. Your reason does not suffer by your choosing one more than the other, for you must choose. That is one point cleared. But your happiness? Let us weigh gain and loss in calling heads that God is. Reckon these two chances: if you win, you win all; if you lose, you lose naught. Then do not hesitate, wager that He is.

Charles Babbage proposed to make an automaton chess-player which should register mechanically the number of games lost and gained in consequence of every sort of move. Thus, the longer the automaton went on playing game, the more experienced it would become by the accumulation of experimental results. Such a machine precisely represents the acquirement of experience by our nervous organization.

During the war years I worked on the development of radar and other radio systems for the R.A.F. and, though gaining much in engineering experience and in understanding people, rapidly forgot most of the physics I had learned.

Experimentation is the least arrogant method of gaining knowledge. The experimenter humbly asks a question of nature.

Far be it from me to suggest that geologists should be reckless in their drafts upon the bank of Time; but nothing whatever is gained, and very much is lost, by persistent niggardliness in this direction.

Historical theories are, after all, intellectual apple carts. They are quite likely to be upset. Nor should it be forgotten that they tend to attract, when they gain ascendancy, a fair number of apple-polishers

I am almost thanking God that I was never educated, for it seems to me that 999 of those who are so, expensively and laboriously, have lost all before they arrive at my age—& remain like Swift's Stulbruggs—cut and dry for life, making no use of their earlier-gained treasures:—whereas, I seem to be on the threshold of knowledge.

I can’t prove it, but I'm pretty sure that people gain a selective advantage from believing in things they can’t prove.

I like a deep and difficult investigation when I happen to have made it easy to myself, if not to all others; and there is a spirit of gambling in this, whether, as by the cast of a die, a calculation è perte de vue shall bring out a beautiful and perfect result or shall be wholly thrown away. Scientific investigations are a sort of warfare carried on in the closet or on the couch against all one's contemporaries and predecessors; I have often gained a signal victory when I have been half asleep, but more frequently have found, upon being thoroughly awake, that the enemy had still the advantage of me, when I thought I had him fast in a corner, and all this you see keeps me alive.

In so far as such developments utilise the natural energy running to waste, as in water power, they may be accounted as pure gain. But in so far as they consume the fuel resources of the globe they are very different. The one is like spending the interest on a legacy, and the other is like spending the legacy itself. ... [There is] a still hardly recognised coming energy problem.

Knowledge once gained casts a faint light beyond its own immediate boundaries. There is no discovery so limited as not to illuminate something beyond itself.

The moral principle inherent in evolution, that nothing can be gained in this world without an effort; the ethical principle inherent in evolution is that only the best has the right to survive; the spiritual principle in evolution is the evidence of beauty, of order, and of design in the daily myriad of miracles to which we owe our existence.

To test a perfect theory with imperfect instruments did not impress the Greek philosophers as a valid way to gain knowledge.

We do not ask what hope of gain makes a little bird warble, since we know that it takes delight in singing because it is for that very singing that the bird was made, so there is no need to ask why the human mind undertakes such toil in seeking out these secrets of the heavens. ... And just as other animals, and the human body, are sustained by food and drink, so the very spirit of Man, which is something distinct from Man, is nourished, is increased, and in a sense grows up on this diet of knowledge, and is more like the dead than the living if it is touched by no desire for these things.

We have not the reverent feeling for the rainbow that a savage has, because we know how it is made. We have lost as much as we gained by prying into that matter.

We set sail on this new sea because there is new knowledge to be gained, and new rights to be won, and they must be won and used for the progress of all people. For space science, like nuclear science and technology, has no conscience of its own. Whether it will become a force for good or ill depends on man, and only if the United States occupies a position of preeminence can we help decide whether this new ocean will be a sea of peace or a new terrifying theater of war.

Where should I start? Start from the statement of the problem. ... What can I do? Visualize the problem as a whole as clearly and as vividly as you can. ... What can I gain by doing so? You should understand the problem, familiarize yourself with it, impress its purpose on your mind.

[Destroying rain forest for economic gain] is like burning a Renaissance painting to cook a meal.