Fundamental Quotes (56 quotes)
A strong feeling of adventure is animating those who are working on bacterial viruses, a feeling that they have a small part in the great drive towards a fundamental problem in biology.
Acceptance without proof is the fundamental characteristic of Western religion, rejection without proof is the fundamental characteristic of Western science.
As agonizing a disease as cancer is, I do not think it can be said that our civilization is threatened by it. … But a very plausible case can be made that our civilization is fundamentally threatened by the lack of adequate fertility control. Exponential increases of population will dominate any arithmetic increases, even those brought about by heroic technological initiatives, in the availability of food and resources, as Malthus long ago realized.
As yet, if a man has no feeling for art he is considered narrow-minded, but if he has no feeling for science this is considered quite normal. This is a fundamental weakness.
Einstein, twenty-six years old, only three years away from crude privation, still a patent examiner, published in the Annalen der Physik in 1905 five papers on entirely different subjects. Three of them were among the greatest in the history of physics. One, very simple, gave the quantum explanation of the photoelectric effect—it was this work for which, sixteen years later, he was awarded the Nobel prize. Another dealt with the phenomenon of Brownian motion, the apparently erratic movement of tiny particles suspended in a liquid: Einstein showed that these movements satisfied a clear statistical law. This was like a conjuring trick, easy when explained: before it, decent scientists could still doubt the concrete existence of atoms and molecules: this paper was as near to a direct proof of their concreteness as a theoretician could give. The third paper was the special eory of relativity, which quietly amalgamated space, time, and matter into one fundamental unity. This last paper contains no references and quotes no authority. All of them are written in a style unlike any other theoretical physicist's. They contain very little mathematics. There is a good deal of verbal commentary. The conclusions, the bizarre conclusions, emerge as though with the greatest of ease: the reasoning is unbreakable. It looks as though he had reached the conclusions by pure thought, unaided, without listening to the opinions of others. To a surprisingly large extent, that is precisely what he had done.
Fortunately I experienced Max Wertheimer's teaching in Berlin and collaborated for over a decade with Wolfgang Köhler. I need not emphasize my debts to these outstanding personalities. The fundamental ideas of Gestalt theory are the foundation of all our investigations in the field of the will, of affection, and of the personality.
Frequently, I have been asked if an experiment I have planned is pure or applied science; to me it is more important to know if the experiment will yield new and probably enduring knowledge about nature. If it is likely to yield such knowledge, it is, in my opinion, good fundamental research; and this is more important than whether the motivation is purely aesthetic satisfaction on the part of the experimenter on the one hand or the improvement of the stability of a high-power transistor on the other.
He who attempts to draw any conclusion whatever as to the nation's wealth or poverty from the mere fact of a favorable or unfavorable Balance of Trade, has not grasped the first fundamental principle of Political Economy.
I regard consciousness as fundamental. I regard matter as derivative from consciousness. We cannot get behind consciousness. Everything that we talk about, everything that we regard as existing, postulates consciousness.
I suspect that the changes that have taken place during the last century in the average man's fundamental beliefs, in his philosophy, in his concept of religion. in his whole world outlook, are greater than the changes that occurred during the preceding four thousand years all put together. ... because of science and its applications to human life, for these have bloomed in my time as no one in history had had ever dreamed could be possible.
If there be an order in which the human race has mastered its various kinds of knowledge, there will arise in every child an aptitude to acquire these kinds of knowledge in the same order. So that even were the order intrinsically indifferent, it would facilitate education to lead the individual mind through the steps traversed by the general mind. But the order is not intrinsically indifferent; and hence the fundamental reason why education should be a repetition of civilization in little.
In medical practice a man may die when, scientifically speaking, he ought to have lived. I have actually known a man to die of a disease from which he was, scientifically speaking, immune. But that does not affect the fundamental truth of science.
It would appear... that moral phenomena, when observed on a great scale, are found to resemble physical phenomena; and we thus arrive, in inquiries of this kind, at the fundamental principle, that the greater the number of individuals observed, the more do individual peculiarities, whether physical or moral, become effaced, and leave in a prominent point of view the general facts, by virtue of which society exists and is preserved.
It's becoming clear that in a sense the cosmos provides the only laboratory where sufficiently extreme conditions are ever achieved to test new ideas on particle physics. The energies in the Big Bang were far higher than we can ever achieve on Earth. So by looking at evidence for the Big Bang, and by studying things like neutron stars, we are in effect learning something about fundamental physics.
Life is order, death is disorder. A fundamental law of Nature states that spontaneous chemical changes in the universe tend toward chaos. But life has, during milliards of years of evolution, seemingly contradicted this law. With the aid of energy derived from the sun it has built up the most complicated systems to be found in the universe—living organisms. Living matter is characterized by a high degree of chemical organisation on all levels, from the organs of large organisms to the smallest constituents of the cell. The beauty we experience when we enjoy the exquisite form of a flower or a bird is a reflection of a microscopic beauty in the architecture of molecules.
Most classifications, whether of inanimate objects or of organisms, are hierarchical. There are 'higher' and 'lower' categories, there are higher and lower ranks. What is usually overlooked is that the use of the term 'hierarchy' is ambiguous, and that two fundamentally different kinds of arrangements have been designated as hierarchical. A hierarchy can be either exclusive or inclusive. Military ranks from private, corporal, sergeant, lieutenant, captain, up to general are a typical example of an exclusive hierarchy. A lower rank is not a subdivision of a higher rank; thus, lieutenants are not a subdivision of captains. The scala naturae, which so strongly dominated thinking from the sixteenth to the eighteenth century, is another good illustration of an exclusive hierarchy. Each level of perfection was considered an advance (or degradation) from the next lower (or higher) level in the hierarchy, but did not include it.
One of the most striking results of modern investigation has been the way in which several different and quite independent lines of evidence indicate that a very great event occurred about two thousand million years ago. The radio-active evidence for the age of meteorites; and the estimated time for the tidal evolution of the Moon's orbit (though this is much rougher), all agree in their testimony, and, what is far more important, the red-shift in the nebulae indicates that this date is fundamental, not merely in the history of our system, but in that of the material universe as a whole.
Pavlov's data on the two fundamental antagonistic nervous processes—stimulation and inhibition—and his profound generalizations regarding them, in particular, that these processes are parts of a united whole, that they are in a state of constant conflict and constant transition of the one to the other, and his views on the dominant role they play in the formation of the higher nervous activity—all those belong to the most established natural—scientific validation of the Marxist dialectal method. They are in complete accord with the Leninist concepts on the role of the struggle between opposites in the evolution, the motion of matter.
Science is beautiful when it makes simple explanations of phenomena or connections between different observations. Examples include the double helix in biology, and the fundamental equations of physics.
[Answer to question: What are the things you find most beautiful in science?]
[Answer to question: What are the things you find most beautiful in science?]
Scientists come in two varieties, hedgehogs and foxes. I borrow this terminology from Isaiah Berlin (1953), who borrowed it from the ancient Greek poet Archilochus. Archilochus told us that foxes know many tricks, hedgehogs only one. Foxes are broad, hedgehogs are deep. Foxes are interested in everything and move easily from one problem to another. Hedgehogs are only interested in a few problems that they consider fundamental, and stick with the same problems for years or decades. Most of the great discoveries are made by hedgehogs, most of the little discoveries by foxes. Science needs both hedgehogs and foxes for its healthy growth, hedgehogs to dig deep into the nature of things, foxes to explore the complicated details of our marvelous universe. Albert Einstein and Edwin Hubble were hedgehogs. Charley Townes, who invented the laser, and Enrico Fermi, who built the first nuclear reactor in Chicago, were foxes.
That our being should consist of two fundamental elements [physical and psychical] offers I suppose no greater inherent improbability than that it should rest on one only.
The advances of biology during the past 20 years have been breathtaking, particularly in cracking the mystery of heredity. Nevertheless, the greatest and most difficult problems still lie ahead. The discoveries of the 1970‘s about the chemical roots of memory in nerve cells or the basis of learning, about the complex behavior of man and animals, the nature of growth, development, disease and aging will be at least as fundamental and spectacular as those of the recent past.
The body of science is not, as it is sometimes thought, a huge coherent mass of facts, neatly arranged in sequence, each one attached to the next by a logical string. In truth, whenever we discover a new fact it involves the elimination of old ones. We are always, as it turns out, fundamentally in error.
The fairest thing we can experience is the mysterious. It is the fundamental emotion which stands at the cradle of true science. He who knows it not, and can no longer wonder, no longer feel amazement, is as good as dead. We all had this priceless talent when we were young. But as time goes by, many of us lose it. The true scientist never loses the faculty of amazement. It is the essence of his being.
The framing of hypotheses is, for the enquirer after truth, not the end, but the beginning of his work. Each of his systems is invented, not that he may admire it and follow it into all its consistent consequences, but that he may make it the occasion of a course of active experiment and observation. And if the results of this process contradict his fundamental assumptions, however ingenious, however symmetrical, however elegant his system may be, he rejects it without hesitation. He allows no natural yearning for the offspring of his own mind to draw him aside from the higher duty of loyalty to his sovereign, Truth, to her he not only gives his affections and his wishes, but strenuous labour and scrupulous minuteness of attention.
The fundamental activity of medical science is to determine the ultimate causation of disease.
The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
The fundamental characteristic of the scientific method is honesty. In dealing with any question, science asks no favors. ... I believe that constant use of the scientific method must in the end leave its impress upon him who uses it. ... A life spent in accordance with scientific teachings would be of a high order. It would practically conform to the teachings of the highest types of religion. The motives would be different, but so far as conduct is concerned the results would be practically identical.
The fundamental concept in social science is Power, in the same sense in which Energy is the fundamental concept in physics.
The fundamental hypothesis of genetic epistemology is that there is a parallelism between the progress made in the logical and rational organization of knowledge and the corresponding formative psychological processes. With that hypothesis, the most fruitful, most obvious field of study would be the reconstituting of human history—the history of human thinking in prehistoric man. Unfortunately, we are not very well informed in the psychology of primitive man, but there are children all around us, and it is in studying children that we have the best chance of studying the development of logical knowledge, physical knowledge, and so forth.
The fundamental idea of these pylons, or great archways, is based on a method of construction peculiar to me, of which the principle consists in giving to the edges of the pyramid a curve of such a nature that this pyramid shall be capable of resisting the force of the wind without necessitating the junction of the edges by diagonals as is usually done.
[Writing of his tower after its completion in 1889.]
[Writing of his tower after its completion in 1889.]
The Fundamental Regulator Paradox ... The task of a regulator is to eliminate variation, but this variation is the ultimate source of information about the quality of its work. Therefore, the better the job a regulator does the less information it gets about how to improve.
The mathematician is entirely free, within the limits of his imagination, to construct what worlds he pleases. What he is to imagine is a matter for his own caprice; he is not thereby discovering the fundamental principles of the universe nor becoming acquainted with the ideas of God. If he can find, in experience, sets of entities which obey the same logical scheme as his mathematical entities, then he has applied his mathematics to the external world; he has created a branch of science.
The more important fundamental laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote. Nevertheless, it has been found that there are apparent exceptions to most of these laws, and this is particularly true when the observations are pushed to a limit, i.e., whenever the circumstances of experiment are such that extreme cases can be examined. Such examination almost surely leads, not to the overthrow of the law, but to the discovery of other facts and laws whose action produces the apparent exceptions. As instances of such discoveries, which are in most cases due to the increasing order of accuracy made possible by improvements in measuring instruments, may be mentioned: first, the departure of actual gases from the simple laws of the so-called perfect gas, one of the practical results being the liquefaction of air and all known gases; second, the discovery of the velocity of light by astronomical means, depending on the accuracy of telescopes and of astronomical clocks; third, the determination of distances of stars and the orbits of double stars, which depend on measurements of the order of accuracy of one-tenth of a second-an angle which may be represented as that which a pin's head subtends at a distance of a mile. But perhaps the most striking of such instances are the discovery of a new planet or observations of the small irregularities noticed by Leverrier in the motions of the planet Uranus, and the more recent brilliant discovery by Lord Rayleigh of a new element in the atmosphere through the minute but unexplained anomalies found in weighing a given volume of nitrogen. Many other instances might be cited, but these will suffice to justify the statement that “our future discoveries must be looked for in the sixth place of decimals.”
The more we split and pulverise matter artificially, the more insistently it proclaims its fundamental unity.
The most fundamental difference between compounds of low molecular weight and macromolecular compounds resides in the fact that the latter may exhibit properties that cannot be deduced from a close examination of the low molecular weight materials. Not very different structures can be obtained from a few building blocks; but if 10,000 or 100,000 blocks are at hand, the most varied structures become possible, such as houses or halls, whose special structure cannot be predicted from the constructions that are possible with only a few building blocks... Thus, a chromosome can be viewed as a material whose macromolecules possess a well defined arrangement, like a living room in which each piece of furniture has its place and not, as in a warehouse, where the pieces of furniture are placed together in a heap without design.
The nucleic acids, as constituents of living organisms, are comparable In importance to proteins. There is evidence that they are Involved In the processes of cell division and growth, that they participate In the transmission of hereditary characters, and that they are important constituents of viruses. An understanding of the molecular structure of the nucleic acids should be of value In the effort to understand the fundamental phenomena of life.
[Co-author with American chemist, B. Corey (1897-1971)]
[Co-author with American chemist, B. Corey (1897-1971)]
The physiological combustion theory takes as its starting point the fundamental principle that the amount of heat that arises from the combustion of a given substance is an invariable quantity–i.e., one independent of the circumstances accompanying the combustion–from which it is more specifically concluded that the chemical effect of the combustible materials undergoes no quantitative change even as a result of the vital process, or that the living organism, with all its mysteries and marvels, is not capable of generating heat out of nothing.
The scientific value of truth is not, however, ultimate or absolute. It rests partly on practical, partly on aesthetic interests. As our ideas are gradually brought into conformity with the facts by the painful process of selection,—for intuition runs equally into truth and into error, and can settle nothing if not controlled by experience,—we gain vastly in our command over our environment. This is the fundamental value of natural science
The suppression of uncomfortable ideas may be common in religion or in politics, but it is not the path to knowledge; it has no in the endeavor of science. We do not know in advance who will discover fundamental insights.
The transition from a paradigm in crisis to a new one from which a new tradition of normal science can emerge is far from a cumulative process, one achieved by an articulation or extension of the old paradigm. Rather it is a reconstruction of the field from new fundamentals, a reconstruction that changes some of the field's most elementary theoretical generalizations as well as many of its paradigm methods and applications. During the transition period there will be a large but never complete overlap between the problems that can be solved by the old and by the new paradigm. But there will also be a decisive difference in the modes of solution. When the transition is complete, the profession will have changed its view of the field, its methods, and its goals.
The velocity of light is one of the most important of the fundamental constants of Nature. Its measurement by Foucault and Fizeau gave as the result a speed greater in air than in water, thus deciding in favor of the undulatory and against the corpuscular theory. Again, the comparison of the electrostatic and the electromagnetic units gives as an experimental result a value remarkably close to the velocity of light–a result which justified Maxwell in concluding that light is the propagation of an electromagnetic disturbance. Finally, the principle of relativity gives the velocity of light a still greater importance, since one of its fundamental postulates is the constancy of this velocity under all possible conditions.
The year 1896 ... marked the beginning of what has been aptly termed the heroic age of Physical Science. Never before in the history of physics has there been witnessed such a period of intense activity when discoveries of fundamental importance have followed one another with such bewildering rapidity.
There has been no discovery like it in the history of man. It puts into man's hands the key to using the fundamental energy of the universe.
There is a reward structure in science that is very interesting: Our highest honors go to those who disprove the findings of the most revered among us. So Einstein is revered not just because he made so many fundamental contributions to science, but because he found an imperfection in the fundamental contribution of Isaac Newton.
This fundamental discovery that all bodies owe their origin to arrangements of single initial corpuscular type is the beacon that lights the history of the universe to our eyes. In its own way, matter obeyed from the beginning that great law of biology to which we shall have to recur time and time again, the law of “complexification.”
Though much new light is shed by ... studies in radioactivity, the nucleus of the atom, with its hoard of energy, thus continues to present us with a fascinating mystery. ... Our assault on atoms has broken down the outer fortifications. We feel that we know the fundamental rules according to which the outer part of the atom is built. The appearance and properties of the electron atmosphere are rather familiar. Yet that inner citadel, the atomic nucleus, remains unconquered, and we have reason to believe that within this citadel is secreted a great treasure. Its capture may form the main objective of the physicists’ next great drive.
Typical of the fundamental scientific problems whose solution should lead to important industrial consequences are, for example, the release of atomic energy, which experiment has shown to exist in quantities millions of times greater than is liberated by combustion.
We are very lucky to be living in an age in which we are still making discoveries. It is like the discovery of America—you only discover it once. The age in which we live is the age in which we are discovering the fundamental laws of nature, and that day will never come again. It is very exciting, it is marvelous, but this excitement will have to go.
We don't know what we are talking about. Many of us believed that string theory was a very dramatic break with our previous notions of quantum theory. But now we learn that string theory, well, is not that much of a break. The state of physics today is like it was when we were mystified by radioactivity. They were missing something absolutely fundamental. We are missing perhaps something as profound as they were back then.
We lay down a fundamental principle of generalization by abstraction: The existence of analogies between central features of various theories implies the existence of a general theory which underlies the particular theories and unifies them with respect to those central features.
We set out, therefore, with the supposition that an organised body is not produced by a fundamental power which is guided in its operation by a definite idea, but is developed, according to blind laws of necessity, by powers which, like those of inorganic nature, are established by the very existence of matter. As the elementary materials of organic nature are not different from those of the inorganic kingdom, the source of the organic phenomena can only reside in another combination of these materials, whether it be in a peculiar mode of union of the elementary atoms to form atoms of the second order, or in the arrangement of these conglomerate molecules when forming either the separate morphological elementary parts of organisms, or an entire organism.
When rich men are thus brought to regard themselves as trustees, and poor men learn to be industrious, economical, temperate, self-denying, and diligent in the acquisition of knowledge, then the deplorable strife between capital and labor, tending to destroy their fundamental, necessary, and irrefragable harmony will cease, and the world will no longer be afflicted with such unnatural industrial conflicts as we have seen during the past century...
[About research with big particle accelerators such as the Large Hadron Collider.] I think the primary justification for this sort of science that we do is fundamental human curiosity. ... It's true, of course, that every previous generation that's made some breakthrough in understanding nature has seen those discoveries translated into new technologies, new possibilities for the human race. That may well happen with the Higgs boson. Quite frankly, at the moment I don't see how you can use the Higgs boson for anything useful.
[Certain students] suppose that because science has penetrated the structure of the atom it can solve all the problems of the universe. ... They are known in every ... college as the most insufferable, cocksure know-it-alls. If you want to talk to them about poetry, they are likely to reply that the "emotive response" to poetry is only a conditioned reflex .... If they go on to be professional scientists, their sharp corners are rubbed down, but they undergo no fundamental change. They most decidedly are not set apart from the others by their intellectual integrity and faith, and their patient humility in front of the facts of nature.... They are uneducated, in the fullest sense of the word, and they certainly are no advertisement for the claims of science teachers.
[T]he history of science has proved that fundamental research is the lifeblood of individual progress and that the ideas that lead to spectacular advances spring from it.