Life through many long periods has been manifested in a countless host of varying structures, all circumscribed by one general plan, each appointed to a definite place, and limited to an appointed duration. On the whole the earth has been thus more and more covered by the associated life of plants and animals, filling all habitable space with beings capable of enjoying their own existence or ministering to the enjoyment of others; till finally, after long preparation, a being was created capable of the wonderful power of measuring and weighing all the world of matter and space which surrounds him, of treasuring up the past history of all the forms of life, and considering his own relation to the whole. When he surveys this vast and co-ordinated system, and inquires into its history and origin, can he be at a loss to decide whether it be a work of Divine thought and wisdom, or the fortunate offspring of a few atoms of matter, warmed by the anima mundi, a spark of electricity, or an accidental ray of sunshine?

My original decision to devote myself to science was a direct result of the discovery which has never ceased to fill me with enthusiasm since my early youth—the comprehension of the far from obvious fact that the laws of human reasoning coincide with the laws governing the sequences of the impressions we receive from the world about us; that, therefore, pure reasoning can enable man to gain an insight into the mechanism of the latter. In this connection, it is of paramount importance that the outside world is something independent from man, something absolute, and the quest for the laws which apply to this absolute appeared to me as the most sublime scientific pursuit in life.

Scientists often invent words to fill the holes in their understanding.These words are meant as conveniences until real understanding can be found. ... Words such as dimension and field and infinity ... are not descriptions of reality, yet we accept them as such because everyone is sure someone else knows what the words mean.

Some years ago John Kenneth Galbraith wrote in an essay on his efforts at writing a history of economics: ‘As one approaches the present, one is filled with a sense of hopelessness; in a year and possibly even a month, there is now more economic comment in the supposedly serious literature than survives from the whole of the thousand years commonly denominated as the Middle Ages ... anyone who claims to be familiar with it all is a confessing liar.’ I believe that all physicists would subscribe to the same sentiments regarding their own professional literature. I do at any rate.

The discrepancy between what was expected and what has been observed has grown over the years, and we're straining harder and harder to fill the gap.
[Commenting on the 1984 article in Nature discrediting neutrinos as the explanation for the missing mass of the universe, leaving astrophysicists more baffled for a solution.]

The human understanding is moved by those things most which strike and enter the mind simultaneously and suddenly, and so fill the imagination; and then it feigns and supposes all other things to be somehow, though it cannot see how, similar to those few things by which it is surrounded.

The rapid growth of industry, the ever increasing population and the imperative need for more varied, wholesome and nourishing foodstuff makes it all the more necessary to exhaust every means at our command to fill the empty dinner pail, enrich our soils, bring greater wealth and influence to our beautiful South land, which is synonymous to a healthy, happy and contented people.

We are now in the mountains and they are in us, kindling enthusiasm, making every nerve quiver, filling every pore and cell of us. Our flesh-and-bone tabernacle seems transparent as glass to the beauty about us, as if truly an inseparable part of it, thrilling with the air and trees, streams and rocks, in the waves of the sun,—a part of all nature, neither old nor young, sick nor well, but immortal.‎