Biology has become as unthinkable without gene-splicing techniques as sending an explorer into the jungle without a compass.
Magazine interview (1981); one year after becoming the first scientist to make bacteria produce a facsimile of human interferon.

Mathematics is not a careful march down a well-cleared highway, but a journey into a strange wilderness, where the explorers often get lost. Rigour should be a signal to the historian that the maps have been made, and the real explorers have gone elsewhere.

Sciences usually advances by a succession of small steps, through a fog in which even the most keen-sighted explorer can seldom see more than a few paces ahead. Occasionally the fog lifts, an eminence is gained, and a wider stretch of territory can be surveyed—sometimes with startling results. A whole science may then seem to undergo a kaleidoscopic rearrangement, fragments of knowledge sometimes being found to fit together in a hitherto unsuspected manner. Sometimes the shock of readjustment may spread to other sciences; sometimes it may divert the whole current of human thought.