In the dog two conditions were found to produce pathological disturbances by functional interference, namely, an unusually acute clashing of the excitatory and inhibitory processes, and the influence of strong and extraordinary stimuli. In man precisely similar conditions constitute the usual causes of nervous and psychic disturbances. Different conditions productive of extreme excitation, such as intense grief or bitter insults, often lead, when the natural reactions are inhibited by the necessary restraint, to profound and prolonged loss of balance in nervous and psychic activity.

Kepler's laws, although not rigidly true, are sufficiently near to the truth to have led to the discovery of the law of attraction of the bodies of the solar system. The deviation from complete accuracy is due to the facts, that the planets are not of inappreciable mass, that, in consequence, they disturb each other's orbits about the Sun, and, by their action on the Sun itself, cause the periodic time of each to be shorter than if the Sun were a fixed body, in the subduplicate ratio of the mass of the Sun to the sum of the masses of the Sun and Planet; these errors are appreciable although very small, since the mass of the largest of the planets, Jupiter, is less than 1/1000th of the Sun's mass.

Man is everywhere a disturbing agent. Wherever he plants his foot, the harmonies of nature are turned to discords.

The bitterness of the potion, and the abhorrence of the patient are necessary circumstances to the operation. It must be something to trouble and disturb the stomach that must purge and cure it.

The equation of animal and vegetable life is too complicated a problem for human intelligence to solve, and we can never know how wide a circle of disturbance we produce in the harmonies of nature when we throw the smallest pebble into the ocean of organic life.

The vacuum-apparatus requires that its manipulators constantly handle considerable amounts of mercury. Mercury is a strong poison, particularly dangerous because of its liquid form and noticeable volatility even at room temperature. Its poisonous character has been rather lost sight of during the present generation. My co-workers and myself found from personal experience-confirmed on many sides when published—that protracted stay in an atmosphere charged with only 1/100 of the amount of mercury required for its saturation, sufficed to induce chronic mercury poisoning. This first reveals itself as an affection of the nerves, causing headaches, numbness, mental lassitude, depression, and loss of memory; such are very disturbing to one engaged in intellectual occupations.

There is a tendency to consider anything in human behavior that is unusual, not well known, or not well understood, as neurotic, psychopathic, immature, perverse, or the expression of some other sort of psychologic disturbance.

There is one great difficulty with a good hypothesis. When it is completed and rounded, the corners smooth and the content cohesive and coherent, it is likely to become a thing in itself, a work of art. It is then like a finished sonnet or a painting completed. One hates to disturb it. Even if subsequent information should shoot a hole in it, one hates to tear it down because it once was beautiful and whole. One of our leading scientists, having reasoned a reef in the Pacific, was unable for a long time to reconcile the lack of a reef, indicated by soundings, with the reef his mind told him was there.

When I hear to-day protests against the Bolshevism of modern science and regrets for the old-established order, I am inclined to think that Rutherford, not Einstein, is the real villain of the piece. When we compare the universe as it is now supposed to be with the universe as we had ordinarily preconceived it, the most arresting change is not the rearrangement of space and time by Einstein but the dissolution of all that we regard as most solid into tiny specks floating in void. That gives an abrupt jar to those who think that things are more or less what they seem. The revelation by modern physics of the void within the atom is more disturbing than the revelation by astronomy of the immense void of interstellar space.