[Recalling Professor Ira Remsen's remarks (1895) to a group of his graduate students about to go out with their degrees into the world beyond the university:]
He talked to us for an hour on what was ahead of us; cautioned us against giving up the desire to push ahead by continued study and work. He warned us against allowing our present accomplishments to be the high spot in our lives. He urged us not to wait for a brilliant idea before beginning independent research, and emphasized the fact the Lavoisier's first contribution to chemistry was the analysis of a sample of gypsum. He told u that the fields in which the great masters had worked were still fruitful; the ground had only been scratched and the gleaner could be sure of ample reward.

And this is the ultimate lesson that our knowledge of the mode of transmission of typhus has taught us: Man carries on his skin a parasite, the louse. Civilization rids him of it. Should man regress, should he allow himself to resemble a primitive beast, the louse begins to multiply again and treats man as he deserves, as a brute beast. This conclusion would have endeared itself to the warm heart of Alfred Nobel. My contribution to it makes me feel less unworthy of the honour which you have conferred upon me in his name.

As I review the nature of the creative drive in the inventive scientists that have been around me, as well as in myself, I find the first event is an urge to make a significant intellectual contribution that can be tangible embodied in a product or process.

But why, it has been asked, did you go there [the Antarctic]? Of what use to civilization can this lifeless continent be? ... [Earlier] expeditions contributed something to the accumulating knowledge of the Antarctic ... that helps us thrust back further the physical and spiritual shadows enfolding our terrestrial existence. Is it not true that one of the strongest and most continuously sustained impulses working in civilization is that which leads to discovery? As long as any part of the world remains obscure, the curiosity of man must draw him there, as the lodestone draws the mariner's needle, until he comprehends its secret.

Evolution is a blind giant who rolls a snowball down a hill. The ball is made of flakes—circumstances. They contribute to the mass without knowing it. They adhere without intention, and without foreseeing what is to result. When they see the result they marvel at the monster ball and wonder how the contriving of it came to be originally thought out and planned. Whereas there was no such planning, there was only a law: the ball once started, all the circumstances that happened to lie in its path would help to build it, in spite of themselves.

From packaging materials, through fibers, foams and surface coatings, to continuous extrusions and large-scale moldings, plastics have transformed almost every aspect of life. Without them, much of modern medicine would be impossible and the consumer electronics and computer industries would disappear. Plastic sewage and water pipes alone have made an immeasurable contribution to public health worldwide.

I am afraid I shall have to give up my trade; I am far too inert to keep up with organic chemistry, it is becoming too much for me, though I may boast of having contributed something to its development. The modern system of formulae is to me quite repulsive.

If someday they say of me that in my work I have contributed something to the welfare and happiness of my fellow man, I shall be satisfied.

In 1944 Erwin Schroedinger, stimulated intellectually by Max Delbruck, published a little book called What is life? It was an inspiration to the first of the molecular biologists, and has been, along with Delbruck himself, credited for directing the research during the next decade that solved the mystery of how 'like begat like.' Max was awarded this Prize in 1969, and rejoicing in it, he also lamented that the work for which he was honored before all the peoples of the world was not something which he felt he could share with more than a handful. Samuel Beckett's contributions to literature, being honored at the same time, seemed to Max somehow universally accessible to anyone. But not his. In his lecture here Max imagined his imprisonment in an ivory tower of science.

In honoring the Wright Brothers, it is customary and proper to recognize their contribution to scientific progress. But I believe it is equally important to emphasize the qualities in their pioneering life and the character in man that such a life produced. The Wright Brothers balanced sucess with modesty, science with simplicity. At Kitty Hawk their intellects and senses worked in mutual support. They represented man in balance, and from that balance came wings to lift a world.

In short, the greatest contribution to real security that science can make is through the extension of the scientific method to the social sciences and a solution of the problem of complete avoidance of war.

My scientific work is motivated by an irresistible longing to understand the secrets of nature and by no other feeling. My love for justice and striving to contribute towards the improvement of human conditions are quite independent from my scientific interests.

Science knows only one commandment—contribute to science.

The advancement of science is slow; it is effected only by virtue of hard work and perseverance. And when a result is attained, should we not in recognition connect it with the efforts of those who have preceded us, who have struggled and suffered in advance? Is it not truly a duty to recall the difficulties which they vanquished, the thoughts which guided them; and how men of different nations, ideas, positions, and characters, moved solely by the love of science, have bequeathed to us the unsolved problem? Should not the last comer recall the researches of his predecessors while adding in his turn his contribution of intelligence and of labor? Here is an intellectual collaboration consecrated entirely to the search for truth, and which continues from century to century.
[Respecting how the work of prior researchers had enabled his isolation of fluorine.]

The attempted synthesis of paleontology and genetics, an essential part of the present study, may be particularly surprising and possibly hazardous. Not long ago, paleontologists felt that a geneticist was a person who shut himself in a room, pulled down the shades, watched small flies disporting themselves in milk bottles, and thought that he was studying nature. A pursuit so removed from the realities of life, they said, had no significance for the true biologist. On the other hand, the geneticists said that paleontology had no further contributions to make to biology, that its only point had been the completed demonstration of the truth of evolution, and that it was a subject too purely descriptive to merit the name 'science'. The paleontologist, they believed, is like a man who undertakes to study the principles of the internal combustion engine by standing on a street corner and watching the motor cars whiz by.

There is a reward structure in science that is very interesting: Our highest honors go to those who disprove the findings of the most revered among us. So Einstein is revered not just because he made so many fundamental contributions to science, but because he found an imperfection in the fundamental contribution of Isaac Newton.

There is no art or science that is too difficult for industry to attain to; it is the gift of tongues, and makes a man understood and valued in all countries, and by all nations; it is the philosopher's stone, that turns all metals, and even stones, into gold, and suffers not want to break into its dwelling; it is the northwest passage, that brings the merchant's ships as soon to him as he can desire: in a word, it conquers all enemies, and makes fortune itself pay contribution.

True optimization is the revolutionary contribution of modern research to decision processes.

We will be able to depart this life with the quiet peace-giving notion, that we were permitted to contribute to the happiness of many who will live after us. In our long lives we endeavored to unfold the collective consciousness. In our lives we have known hell and heaven; the final balance, however, is that we helped pave the way to dynamic harmony in this earthly house. That, I believe, is the meaning of this live.

[The] complex pattern of the misallocation of credit for scientific work must quite evidently be described as 'the Matthew effect', for, as will be remembered, the Gospel According to St. Matthew puts it this way: For unto every one that hath shall be given, and he shall have abundance: but from him that hath not shall be taken away even that which he hath. Put in less stately language, the Matthew effect consists of the accruing of greater increments of recognition for particular scientific contributions to scientists of considerable repute and the withholding of such recognition from scientists who have not yet made their mark.