A parable: A man was examining the construction of a cathedral. He asked a stone mason what he was doing chipping the stones, and the mason replied, “I am making stones.” He asked a stone carver what he was doing. “I am carving a gargoyle.” And so it went, each person said in detail what they were doing. Finally he came to an old woman who was sweeping the ground. She said. “I am helping build a cathedral.”
...Most of the time each person is immersed in the details of one special part of the whole and does not think of how what they are doing relates to the larger picture.
[For example, in education, a teacher might say in the next class he was going to “explain Young's modulus and how to measure it,” rather than, “I am going to educate the students and prepare them for their future careers.”]

Architecture is of all the arts the one nearest to a science, for every architectural design is at its inception dominated by scientific considerations. The inexorable laws of gravitation and of statics must be obeyed by even the most imaginative artist in building.

Astronomers have built telescopes which can show myriads of stars unseen before; but when a man looks through a tear in his own eye, that is a lens which opens reaches into the unknown, and reveals orbs which no telescope, however skilfully constructed, could do.

But the strong base and building of my love
Is as the very centre of the earth,
Drawing all things to 't.

Chemistry is one of those branches of human knowledge which has built itself upon methods and instruments by which truth can presumably be determined. It has survived and grown because all its precepts and principles can be re-tested at any time and anywhere. So long as it remained the mysterious alchemy by which a few devotees, by devious and dubious means, presumed to change baser metals into gold, it did not flourish, but when it dealt with the fact that 56 g. of fine iron, when heated with 32 g. of flowers of sulfur, generated extra heat and gave exactly 88 g. of an entirely new substance, then additional steps could be taken by anyone. Scientific research in chemistry, since the birth of the balance and the thermometer, has been a steady growth of test and observation. It has disclosed a finite number of elementary reagents composing an infinite universe, and it is devoted to their inter-reaction for the benefit of mankind.

Computers and rocket ships are examples of invention, not of understanding. ... All that is needed to build machines is the knowledge that when one thing happens, another thing happens as a result. It's an accumulation of simple patterns. A dog can learn patterns. There is no “why&rdqo; in those examples. We don't understand why electricity travels. We don't know why light travels at a constant speed forever. All we can do is observe and record patterns.

Every new discovery of science is a further 'revelation' of the order which God has built into His universe.

Evolution is a blind giant who rolls a snowball down a hill. The ball is made of flakes—circumstances. They contribute to the mass without knowing it. They adhere without intention, and without foreseeing what is to result. When they see the result they marvel at the monster ball and wonder how the contriving of it came to be originally thought out and planned. Whereas there was no such planning, there was only a law: the ball once started, all the circumstances that happened to lie in its path would help to build it, in spite of themselves.

Houses were knocked down... enormous heaps of earth and clay thrown up; buildings that were undermined and shaking, propped up by great beams of wood... The yet unfinished and unopened Railway was in progress.

I hope that in due time the chemists will justify their proceedings by some large generalisations deduced from the infinity of results which they have collected. For me I am left hopelessly behind and I will acknowledge to you that through my bad memory organic chemistry is to me a sealed book. Some of those here, Hoffman [August Hofmann] for instance, consider all this however as scaffolding, which will disappear when the structure is built. I hope the structure will be worthy of the labour. I should expect a better and a quicker result from the study of the powers of matter, but then I have a predilection that way and am probably prejudiced in judgment.

If you have built castles in the air, your work need not be lost; that is where they should be. Now put the foundations under them.

In general, a fact is worth more than theories in the long run. The theory stimulates, but the fact builds. The former in due time is replaced by one better but the fact remains and becomes fertile.

It is both a sad and a happy fact of engineering history that disasters have been powerful instruments of change. Designers learn from failure. Industrial society did not invent grand works of engineering, and it was not the first to know design failure. What it did do was develop powerful techniques for learning from the experience of past disasters. It is extremely rare today for an apartment house in North America, Europe, or Japan to fall down. Ancient Rome had large apartment buildings too, but while its public baths, bridges and aqueducts have lasted for two thousand years, its big residential blocks collapsed with appalling regularity. Not one is left in modern Rome, even as ruin.

It is structure that we look for whenever we try to understand anything. All science is built upon this search; we investigate how the cell is built of reticular material, cytoplasm, chromosomes; how crystals aggregate; how atoms are fastened together; how electrons constitute a chemical bond between atoms. We like to understand, and to explain, observed facts in terms of structure. A chemist who understands why a diamond has certain properties, or why nylon or hemoglobin have other properties, because of the different ways their atoms are arranged, may ask questions that a geologist would not think of' formulating, unless he had been similarly trained in this way of thinking about the world.

Nature has but one plan of operation, invariably the same in the smallest things as well as in the largest, and so often do we see the smallest masses selected for use in Nature, that even enormous ones are built up solely by fitting these together. Indeed, all Nature's efforts are devoted to uniting the smallest parts of our bodies in such a way that all things whatsoever, however diverse they may be, which coalesce in the structure of living things construct the parts by means of a sort of compendium.

One hardly knows where, in the history of science, to look for an important movement that had its effective start in so pure and simple an accident as that which led to the building of the great Washington telescope, and went on to the discovery of the satellites of Mars.

Our model of Nature should not be like a building—a handsome structure for the populace to admire, until in the course of time some one takes away a corner stone and the edifice comes toppling down. It should be like an engine with movable parts. We need not fix the position of any one lever; that is to be adjusted from time to time as the latest observations indicate. The aim of the theorist is to know the train of wheels which the lever sets in motion—that binding of the parts which is the soul of the engine.

Perhaps the central problem we face in all of computer science is how we are to get to the situation where we build on top of the work of others rather than redoing so much of it in a trivially different way.

perhaps to move
His laughter at their quaint opinions wide
Hereafter; when they come to model heav'n,
And calculate the stars, how they will wield
The mighty frame; how build, un-build, contrive,
To save appearances; how gird the sphere With centric and eccentric scribbled o'er, Cycle and epicycle, orb in orb.

Science flies you to the moon. Religion flies you into buildings.

Science is a magnificent force, but it is not a teacher of morals. It can perfect machinery, but it adds no moral restraints to protect society from the misuse of the machine. It can also build gigantic intellectual ships, but it constructs no moral rudders for the control of storm tossed human vessel. It not only fails to supply the spiritual element needed but some of its unproven hypotheses rob the ship of its compass and thus endangers its cargo.

The bell ringing for church, we went thither immediately, and with hearts full of gratitude, returned sincere thanks to God for the mercies we had received: were I a Roman Catholic, perhaps I should on this occasion vow to build a chapel to some saint, but as I am not, if I were to vow at all, it should be to build a light-house. [Upon narrowly missing a shipwreck on the Scilly rocks.]
[Frequently seen summarized as, though not Franklin's own wording: Lighthouses are more helpful than churches.

The laws of nature are the rules according to which the effects are produced; but there must be a cause which operates according to these rules. The laws of navigation never navigated a ship. The rules of architecture never built a house.

The progress of synthesis, or the building up of natural materials from their constituent elements, proceeds apace. Even some of the simpler albuminoids, a class of substances of great importance in the life process, have recently been artificially prepared. ... Innumerable entirely new compounds have been produced in the last century. The artificial dye-stuffs, prepared from materials occurring in coal-tar, make the natural colours blush. Saccharin, which is hundreds of times sweeter than sugar, is a purely artificial substance. New explosives, drugs, alloys, photographic substances, essences, scents, solvents, and detergents are being poured out in a continuous stream.

These days malls are the cathedrals of the modern world, and old buildings that had character are gone to allow for econo-worship and peso-pilgrimages.

This Academy [at Lagado] is not an entire single Building, but a Continuation of several Houses on both Sides of a Street; which growing waste, was purchased and applied to that Use.
I was received very kindly by the Warden, and went for many Days to the Academy. Every Room hath in it ' one or more Projectors; and I believe I could not be in fewer than five Hundred Rooms.
The first Man I saw was of a meagre Aspect, with sooty Hands and Face, his Hair and Beard long, ragged and singed in several Places. His Clothes, Shirt, and Skin were all of the same Colour. He had been Eight Years upon a Project for extracting Sun-Beams out of Cucumbers, which were to be put into Vials hermetically sealed, and let out to warm the Air in raw inclement Summers. He told me, he did not doubt in Eight Years more, that he should be able to supply the Governor's Gardens with Sunshine at a reasonable Rate; but he complained that his Stock was low, and interested me to give him something as an Encouragement to Ingenuity, especially since this had been a very dear Season for Cucumbers. I made him a small Present, for my Lord had furnished me with Money on purpose, because he knew their Practice of begging from all who go to see them.
I saw another at work to calcine Ice into Gunpowder; who likewise shewed me a Treatise he had written concerning the Malleability of Fire, which he intended to publish.
There was a most ingenious Architect who had contrived a new Method for building Houses, by beginning at the Roof, and working downwards to the Foundation; which he justified to me by the life Practice of those two prudent Insects the Bee and the Spider.
In another Apartment I was highly pleased with a Projector, who had found a device of plowing the Ground with Hogs, to save the Charges of Plows, Cattle, and Labour. The Method is this: In an Acre of Ground you bury at six Inches Distance, and eight deep, a quantity of Acorns, Dates, Chestnuts, and other Masts or Vegetables whereof these Animals are fondest; then you drive six Hundred or more of them into the Field, where in a few Days they will root up the whole Ground in search of their Food, and make it fit for sowing, at the same time manuring it with their Dung. It is true, upon Experiment they found the Charge and Trouble very great, and they had little or no Crop. However, it is not doubted that this Invention may be capable of great Improvement.
I had hitherto seen only one Side of the Academy, the other being appropriated to the Advancers of speculative Learning.
Some were condensing Air into a dry tangible Substance, by extracting the Nitre, and letting the acqueous or fluid Particles percolate: Others softening Marble for Pillows and Pin-cushions. Another was, by a certain Composition of Gums, Minerals, and Vegetables outwardly applied, to prevent the Growth of Wool upon two young lambs; and he hoped in a reasonable Time to propagate the Breed of naked Sheep all over the Kingdom.

To feed applied science by starving basic science is like economising on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles.

We have dominated and overruled nature, and from now on the earth is ours, a kitchen garden until we learn to make our own chlorophyll and float it out in the sun inside plastic mebranes. We will build Scarsdale on Mount Everest.

You bring me the deepest joy that can be felt by a man whose invincible belief is that Science and Peace will triumph over Ignorance and War, that nations will unite, not to destroy, but to build, and that the future will belong to those who will have done most for suffering humanity.