The existence of life must be considered as an elementary fact that can not be explained, but must be taken as a starting point in biology, in a similar way as the quantum of action, which appears as an irrational element from the point of view of classical mechanical physics, taken together with the existence of elementary particles, forms the foundation of atomic physics. The asserted impossibility of a physical or chemical explanation of the function peculiar to life would in this sense be analogous to the insufficiency of the mechanical analysis for the understanding of the stability of atoms.

The totality of our so-called knowledge or beliefs, from the most casual matters of geography and history to the profoundest laws of atomic physics or even of pure mathematics and logic, is a man-made fabric which impinges on experience only along the edges. Or, to change the figure, total science is like a field of force whose boundary conditions are experience.

[Regarding mathematics,] there are now few studies more generally recognized, for good reasons or bad, as profitable and praiseworthy. This may be true; indeed it is probable, since the sensational triumphs of Einstein, that stellar astronomy and atomic physics are the only sciences which stand higher in popular estimation.