Further, it will not be amiss to distinguish the three kinds and, as it were, grades of ambition in mankind. The first is of those who desire to extend their own power in their native country, a vulgar and degenerate kind. The second is of those who labor to extend the power and dominion of their country among men. This certainly has more dignity, though not less covetousness. But if a man endeavor to establish and extend the power and dominion of the human race itself over the universe, his ambition (if ambition it can be called) is without doubt both a more wholesome and a more noble thing than the other two. Now the empire of man over things depends wholly on the arts and sciences. For we cannot command nature except by obeying her.

I have no desire to write my own biography, as long as I have strength and means to do better work.

Let us see how high we can fly before the sun melts the wax in our wings.
About the ambitious pursuit of knowledge, alluding to Icarus of the Greek myth.

Our ambition should be to rule ourselves, the true kingdom for each one of us; and true progress is to know more, and be more, and to do more.

Science in England is not a profession: its cultivators are scarcely recognised even as a class. Our language itself contains no single term by which their occupation can be expressed. We borrow a foreign word [Savant] from another country whose high ambition it is to advance science, and whose deeper policy, in accord with more generous feelings, gives to the intellectual labourer reward and honour, in return for services which crown the nation with imperishable renown, and ultimately enrich the human race.

The Commonwealth of Learning is not at this time without Master-Builders, whose mighty Designs, in advancing the Sciences, will leave lasting Monuments to the Admiration of Posterity; But every one must not hope to be a Boyle, or a Sydenham; and in an Age that produces such Masters, as the Great-Huygenius, and the incomparable Mr. Newton, with some other of that Strain; 'tis Ambition enough to be employed as an Under-Labourer in clearing Ground a little, and removing some of the Rubbish, that lies in the way to Knowledge.

To me there never has been a higher source of honour or distinction than that connected with advances in science. I have not possessed enough of the eagle in my character to make a direct flight to the loftiest altitudes in the social world; and I certainly never endeavored to reach those heights by using the creeping powers of the reptile, who in ascending, generally chooses the dirtiest path, because it is the easiest.