“The occurrence of an internal skeleton, in definite relations to the other organ systems, and the articulation of the body into homologous segments, are points in the general organization of Vertebrates to which especial weight must be given. This metameric structure is more or less definitely expressed in most of the organs, and as it extends to the axial skeleton, the latter also gradually articulates into separate segments, the vertebrae. The latter, however, must be regarded only as the partial expression of a general articulation of the body which is all the more important in consequence of its appearing prior to the articulation of the originally inarticulate axial skeleton. Hence this general articulation may be considered as a primitive vertebral structure, to which the articulation of the axial skeleton is related as a secondary process of the same sort.”