... If I let myself believe anything on insufficient evidence, there may be no great harm done by the mere belief; it may be true after all, or I may never have occasion to exhibit it in outward acts. But I cannot help doing this great wrong towards Man, that I make myself credulous. The danger to society is not merely that it should believe wrong things, though that is great enough; but that it should become credulous, and lose the habit of testing things and inquiring into them; for then it must sink back into savagery.

Newton supposed that the case of the planet was similar to that of [a ball spun around on the end of an elastic string]; that it was always pulled in the direction of the sun, and that this attraction or pulling of the sun produced the revolution of the planet, in the same way that the traction or pulling of the elastic string produces the revolution of the ball. What there is between the sun and the planet that makes each of them pull the other, Newton did not know; nobody knows to this day; and all we are now able to assert positively is that the known motion of the planet is precisely what would be produced if it were fastened to the sun by an elastic string, having a certain law of elasticity. Now observe the nature of this discovery, the greatest in its consequences that has ever yet been made in physical science:—
I. It begins with an hypothesis, by supposing that there is an analogy between the motion of a planet and the motion of a ball at the end of a string.
II. Science becomes independent of the hypothesis, for we merely use it to investigate the properties of the motion, and do not trouble ourselves further about the cause of it.

Remember that [scientific thought] is the guide of action; that the truth which it arrives at is not that which we can ideally contemplate without error, but that which we may act upon without fear; and you cannot fail to see that scientific thought is not an accompaniment or condition of human progress, but human progress itself.

The aim of scientific thought, then, is to apply past experience to new circumstances; the instrument is an observed uniformity in the course of events. By the use of this instrument it gives us information transcending our experience, it enables us to infer things that we have not seen from things that we have seen; and the evidence for the truth of that information depends on our supposing that the uniformity holds good beyond our experience.

The scientific discovery appears first as the hypothesis of an analogy; and science tends to become independent of the hypothesis.

We may always depend on it that algebra, which cannot be translated into good English and sound common sense, is bad algebra.

… scientific thought does not mean thought about scientific subjects with long names. There are no scientific subjects. The subject of science is the human universe; that is to say, everything that is, or has been, or may be related to man.